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Vitamin D may help prevent dental caries

A new review of existing studies points toward a potential role for vitamin D in helping to prevent dental caries, or tooth decay.

28 Nov 2012

Microneedle-based measles vaccine can immunize against measles

Measles vaccine given with painless and easy-to-administer microneedle patches can immunize against measles at least as well as vaccine given with conventional hypodermic needles, according to research done by the Georgia Institute of Technology and the Centers for Disease Control and Prevention (CDC).

28 Nov 2012

FDA grants final approval to Cobrek’s generic Luxiq foam NDA for treatment of scalp psoriasis

Perrigo Company today announced that its partner, Cobrek Pharmaceuticals, Inc., received final approval from the U.S. Food and Drug Administration for its Abbreviated New Drug Application (ANDA) for betamethasone valerate foam 0.12%, the generic equivalent of Luxiq Foam.

28 Nov 2012

Topically applied simvastatin enhances wound recovery in diabetic mice

Delayed wound healing is a major complication of diabetes because the physiological changes in tissues and cells impair the wound healing process. This can result in additional disease outcomes such as diabetic foot ulcer, a significant cause of morbidity in the growing population of diabetic patients. A new study has found that topically applied simvastatin accelerates wound healing in diabetic mice, suggesting important implications for humans with diabetes.

28 Nov 2012

Study identifies gene signature associated with resistance to cancer therapies

Agendia, an innovative molecular cancer diagnostics company and leader in personalized medicine, today announced the publication in the November 21st issue of the prestigious scientific journal "Cell" of a study that identifies a gene signature that is associated with resistance to a broad range of cancer therapies in multiple cancer types.

28 Nov 2012

Gilead Sciences receives EC approval for Viread to treat HIV-1 infected children

Gilead Sciences, Inc. today announced that the European Commission has granted marketing authorization for two new indications for once-daily Viread (tenofovir disoproxil fumarate).

28 Nov 2012

National Taiwan University Hospital, PAREXEL establish alliance

PAREXEL International Corporation a leading global biopharmaceutical services provider, and the National Taiwan University Hospital (NTUH) announced today that they have established an alliance. Under the agreement, PAREXEL and NTUH will collaborate to provide drug development services in Taiwan.

From Parexel 27 Nov 2012

Specific combination of two pharmaceutical substances show promise against multiple sclerosis

A new substance class for the treatment of multiple sclerosis and other neurodegenerative diseases now promises increased efficacy paired with fewer side effects. To achieve this, a team of scientists under the leadership of Prof. Gunter Fischer and Dr. Frank Striggow have combined two already approved pharmaceutical substances with each other using a chemical linker structure.

27 Nov 2012

Recognizing pharmaceutical philanthropy's role in fighting NTDs

"In October 1987, Roy Vagelos, then the chief executive of pharmaceutical company Merck, launched the largest pharmaco-philanthropic venture ever," William Foege, an epidemiologist and former director of the CDC, writes in a Washington Post opinion piece highlighting the company's efforts to combat onchocerciasis in the developing world through the free distribution of its drug Mectizan.

27 Nov 2012

Buying mail-order medications may encourage patients to stick their treatments

Patients newly prescribed a cholesterol-lowering medication were more likely to pick it up from the pharmacy if they received automated phone and mail reminders, according to a study published in the Archives of Internal Medicine today.

27 Nov 2012

Clinics on Cambodian-Thai border aim to prevent spread of drug-resistant malaria

BBC News examines "a worrying drop in the effectiveness of the artemisinin-based drugs" against malaria along the Cambodian-Thai border, and how clinics are attempting to combat the trend by offering monetary incentives to patients to complete treatment regimens.

27 Nov 2012

Anesthetics can help reduce risk of cardiac surgery drug-associated seizures

Two drugs commonly given during cardiac surgery can lead to convulsive seizures, but anesthetics can help cut the risk, according to new research from the Faculty of Medicine at the University of Toronto.

27 Nov 2012

California researchers develop new strategy to find novel antibiotics for bacterial infections

Researchers at the University of California, Santa Cruz, have developed a new strategy for finding novel antibiotic compounds, using a diagnostic panel of bacterial strains for screening chemical extracts from natural sources.

27 Nov 2012

Low folate and vitamin B12 intake increase risk of melancholic depressive symptoms

A low intake of folate and vitamin B12 increases the risk of melancholic depressive symptoms, according to a study among nearly 3,000 middle-aged and elderly Finnish subjects. On the other hand, non-melancholic depressive symptoms are associated with an increased risk for the metabolic syndrome.

27 Nov 2012

EC approves Regeneron’s EYLEA for treatment of wet AMD

Regeneron Pharmaceuticals, Inc. today announced that EYLEA (aflibercept) Injection has been approved by the European Commission for the treatment of patients with neovascular (wet) age-related macular degeneration (wet AMD).

27 Nov 2012

Routine HIV testing can reduce illness and death across Canada

Offering routine HIV testing to the general population rather than only to high-risk individuals will significantly reduce illness and death, argues Dr. Julio Montaner and coauthors in an editorial in CMAJ (Canadian Medical Association Journal).

27 Nov 2012

Chemotherapy can induce brain changes that may affect concentration and memory

Chemotherapy can induce changes in the brain that may affect concentration and memory, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

27 Nov 2012

Experimental flu vaccine technique could reduce time needed to develop new shots for humans

"An experimental vaccine based on a molecule related to DNA protects animals against influenza and may one day offer an ultra-rapid way to develop new shots for humans, German scientists reported on Sunday," Reuters reports.

27 Nov 2012

Viewpoints: Sen. Corker's plan to avoid the 'fiscal cliff'; Romney's brave attempt to deal with health entitlements; Fixing the drug shortage

I have shared with House and Senate leaders as well as the White House a 242-page bill that, along with other agreed-upon cuts that are to be enacted, would produce $4.5 trillion in fiscal reforms and replace sequestration.

27 Nov 2012

Antifibrinolytics inhibit glycine receptor activity in the brain and cause seizures

Antifibrinolytic drugs are frequently used to prevent blood loss during surgery, but sometimes cause convulsive seizures. In this issue of the Journal of Clinical Investigation, researchers led by Beverly Orser at the University of Toronto investigated the molecular mechanisms that underlie this side effect.

27 Nov 2012

Pharmaceutical News

Vitamin D may help prevent dental caries

Microneedle-based measles vaccine can immunize against measles

FDA grants final approval to Cobrek’s generic Luxiq foam NDA for treatment of scalp psoriasis

Topically applied simvastatin enhances wound recovery in diabetic mice

Study identifies gene signature associated with resistance to cancer therapies

Gilead Sciences receives EC approval for Viread to treat HIV-1 infected children

National Taiwan University Hospital, PAREXEL establish alliance

Specific combination of two pharmaceutical substances show promise against multiple sclerosis

Recognizing pharmaceutical philanthropy's role in fighting NTDs

Buying mail-order medications may encourage patients to stick their treatments

Clinics on Cambodian-Thai border aim to prevent spread of drug-resistant malaria

Anesthetics can help reduce risk of cardiac surgery drug-associated seizures

California researchers develop new strategy to find novel antibiotics for bacterial infections

Low folate and vitamin B12 intake increase risk of melancholic depressive symptoms

EC approves Regeneron’s EYLEA for treatment of wet AMD

Routine HIV testing can reduce illness and death across Canada

Chemotherapy can induce brain changes that may affect concentration and memory

Experimental flu vaccine technique could reduce time needed to develop new shots for humans

Viewpoints: Sen. Corker's plan to avoid the 'fiscal cliff'; Romney's brave attempt to deal with health entitlements; Fixing the drug shortage

Antifibrinolytics inhibit glycine receptor activity in the brain and cause seizures

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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