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Positive preclinical results from Cancer Therapeutics' CTX-0294945 plus Avastin study

Cancer Therapeutics, a company focused on translating cancer biology research into novel treatments for cancer, today announced positive preclinical results for CTX-0294945 as an adjuvant therapy to the cancer drug Avastin (bevacizumab - Genentech/Roche). The data is presented today in a late breaking poster at the American Association for Cancer Research (AACR) Annual Meeting 2012 in Chicago, USA.

4 Apr 2012

Scientists discover why rapamycin causes diabetic-like symptoms in patients

Scientists at Dana-Farber Cancer Institute have discovered why diabetic-like symptoms develop in some patients given rapamycin, an immune-suppressant drug that also has shown anti-cancer activity and may even slow ageing.

4 Apr 2012

Combination of ADHD drug and parental intervention can help children with autism

Researchers at The Ohio State University are conducting a study to determine which is more effective for helping children on the autism spectrum: training parents or taking medication.

4 Apr 2012

New initiative aims to strengthen regulatory capacity, systems for delivery of medicines in Africa

"The need to ensure that people in Africa have access to essential, high quality, safe and affordable medicines has just received a major boost with the launch of the East African Community (EAC) Medicines Registration Harmonization Project in Arusha, Tanzania, on 30 March 2011," UNAIDS reports in a feature story on its website.

4 Apr 2012

Scientists discover new anti-HCV antibodies

A team led by scientists at The Scripps Research Institute has found antibodies that can prevent infection from widely differing strains of hepatitis C virus (HCV) in cell culture and animal models.

4 Apr 2012

SFU receives NIH grant to develop effective HIV/AIDS vaccine

Jamie Scott, a Simon Fraser University professor and Canada Research Chair in molecular immunity, and three international collaborators are getting a hefty financial boost in their efforts to develop an effective HIV/AIDS vaccine.

4 Apr 2012

Young girls face increased risk of side effects after Gardasil vaccination

Younger girls are more likely than adult women to report side effects after receiving Gardasil, the human papillomavirus vaccine.

4 Apr 2012

Gamma-linoleic acid can inhibit growth of pancreatic cancer cells

The dietary supplement gamma-linoleic acid can inhibit the growth of a subset of pancreatic cancer cells and selectively promote cancer cell death in mice, a Mayo Clinic study has found.

4 Apr 2012

Vitamin D deficiency may increase risk of mortality in intensive care patients

Scientists have long believed that vitamin D, which is naturally absorbed from sunlight, has an important role in the functioning of the body's autoimmune system. Now Prof. Howard Amital of Tel Aviv University's Sackler Faculty of Medicine and Sheba Medical Center has discovered that the vitamin may also affect the outcomes of patients in intensive care.

4 Apr 2012

Navidea announces FDA extension of Lymphoseek PDUFA date by three months

Navidea Biopharmaceuticals, Inc. today announced that yesterday it received notification from the United States Food and Drug Administration (FDA) that the Prescription Drug User Fee Act (PDUFA) date for 99m-Tc-Tilmanocept, has been modified to September 10, 2012, a 90-day extension from the initial PDUFA date of June 10th.

4 Apr 2012

Researchers figure out how rapamycin causes diabetes

The drug known as rapamycin is widely used by cancer and transplant patients, and there are hints that it might even help us put off old age and live longer. But, it also comes with a downside: rapamycin leads to diabetes in as many as 15 percent of the people who take it.

4 Apr 2012

Mylan introduces Mesna Injection

Mylan Inc. today announced that its Mylan Institutional business has launched Mesna Injection, 100 mg/mL, packaged in 1,000 mg/10mL multiple-dose vials.

4 Apr 2012

TL32711 compound targets key pathway in lymphoma

Scientists at Fox Chase Cancer Center in Philadelphia have come one step closer to developing the first treatment to target a key pathway in lymphoma. The new findings will be announced at the AACR Annual Meeting 2012 on Tuesday, April 3.

4 Apr 2012

Federal Trade Commission OKs $29 billion merger by Express Scripts, Medco

By a three-to-one vote, regulators approved Express Scripts' plan to purchase Medco, ending an eight-month inquiry into whether the deal would stifle competition in the pharmacy benefits industry.

3 Apr 2012

Doctors more reluctant to start their patients on insulin

Doctors are more reluctant to start their patients on insulin than the patients are themselves, according to a new study led by researchers at St. Michael's Hospital.

3 Apr 2012

Prenatal antipsychotic drug exposure may reduce scores on infant neuromotor screening

Among 6-month-old infants, a history of intrauterine antipsychotic medication exposure was associated with significantly lower scores on a standard test of neuromotor performance, according to a report published Online First by Archives of General Psychiatry, a JAMA Network publication.

3 Apr 2012

Study shows how morphine creates inflammatory response in the brain

An international team of researchers involving the University of Adelaide and University of Colorado has made a major discovery that could lead to more effective treatment of severe pain using morphine.

3 Apr 2012

Older maternal age, fertility treatments account for marked increase in twin births

Women having children at older ages and the growing availability of fertility treatments has led to a marked increase in the birth of twins: In 2009, one in every 30 babies born in the United States was a twin compared with one in every 53 in 1980.

3 Apr 2012

State capitols: Social issues a hot topic; Iowa short on time for state budget; Kansas advances drug bills

Legislatures in Iowa and Kansas consider bills on health care, while Stateline looks at the social issues debates going on in many state capitols around the nation.

3 Apr 2012

TLR4/MD-2 protein complex triggers morphine-induced inflammation

A University of Colorado Boulder-led research team has discovered that two protein receptors in the central nervous system team up to respond to morphine and cause unwanted neuroinflammation, a finding with implications for improving the efficacy of the widely used painkiller while decreasing its abuse potential.

3 Apr 2012