Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Study reveals how devastating mitochondrial diseases strike families without any previous history

Researchers have shown for the first time how children can inherit a severe - potentially fatal - mitochondrial disease from a healthy mother.

15 Jan 2018

Mitochondrial impairment may actually protect the brain in Parkinson's disease, study shows

A Norwegian study shows that impairment in mitochondria may actually protect the brain in Parkinson's disease.

15 Jan 2018

Whole of Britain to be put on a diet plan come March

New Year resolutions have not been broken yet and Public Health England is coming up with a set of new guidelines for healthier eating. The entire country needs to watch calories and PHE is coming up with the “calorie caps” on all meals come March this year.

15 Jan 2018

U.S. FDA approves first drug for patients with germline BRCA-mutated metastatic breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has approved LYNPARZA (olaparib) for use in patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer who have been previously treated with chemotherapy in the neoadjuvant, adjuvant or metastatic setting.

12 Jan 2018

Researchers use novel PET tracer to assess myelin damage in mouse models of MS

The loss or damage of myelin, a cellular sheath that surrounds and insulates nerves, is the hallmark of the immune-mediated neurological disorder multiple sclerosis.

12 Jan 2018

Study finds overall pattern of commonality between Huntington's and Parkinson's

A new study strongly suggests that the brains of people who have died of Huntington's disease (HD) and Parkinson's disease (PD) show a similar response to a lifetime of neurodegeneration, despite being two very distinct diseases.

12 Jan 2018

Worsening of anxiety symptoms may be early indicator of Alzheimer's disease

A new study suggests an association between elevated amyloid beta levels and the worsening of anxiety symptoms. The findings support the hypothesis that neuropsychiatric symptoms could represent the early manifestation of Alzheimer's disease in older adults.

12 Jan 2018

Novel polygenic hazard score captures age variations of aggressive prostate cancer

An international team, led by researchers at the University of California San Diego School of Medicine, has developed and validated a genetic tool for predicting age of onset of aggressive prostate cancer, a disease that kills more than 26,000 American men annually.

12 Jan 2018

Insilico Medicine develops new deep-learning based hematological human aging clock

Today, Insilico Medicine, Inc., a Baltimore-based company specializing in the application of artificial intelligence for drug discovery, biomarker development and aging research, announced a publication of a research paper titled "Population-specific biomarkers of human aging: a big data study using South Korean, Canadian and Eastern-European patient populations" in The Journal of Gerontology.

11 Jan 2018

For elder health, trips to the ER are often a tipping point

Twice a day, the 86-year-old man went for long walks and visited with neighbors along the way. Then, one afternoon he fell while mowing his lawn. In the emergency room, doctors diagnosed a break in his upper arm and put him in a sling.

11 Jan 2018

Pfizer to stop Alzheimer’s and Parkinson’s disease research

Pharmaceutical giant Pfizer has announced its intention to stop research and development in areas including Alzheimer’s disease and Parkinson’s disease.

11 Jan 2018

Salk scientists identify molecular target of experimental Alzheimer’s drug

The experimental drug J147 is something of a modern elixir of life; it's been shown to treat Alzheimer's disease and reverse aging in mice and is almost ready for clinical trials in humans.

10 Jan 2018

Alzheimer’s Research UK calls on pharma to continue supporting dementia research

Alzheimer’s Research UK is calling for a recommitment from pharmaceutical companies to continue efforts to fund research into dementia, the leading cause of death in the UK.

10 Jan 2018

General anesthesia may be more complex in its workings than we know now

Associate Professor Bruno van Swinderen from Queensland Brain Institute, University of Queensland with his colleagues have studied the workings of general anesthetics on the brain and found that these agents did more than just put a person to sleep. These findings could pave the way for better and more effective anesthetics they believe. The study was published in the latest issue of the journal Cell Reports.

10 Jan 2018

Researchers awarded grant to repurpose FDA-approved drugs for treating Alzheimer's patients

Researchers from Case Western Reserve University School of Medicine and collaborators have received a five-year, $2.8 million grant from the National Institute on Aging to identify FDA-approved medications that could be repurposed to treat Alzheimer's disease.

9 Jan 2018

Vanderbilt and Lundbeck collaborate to develop novel approach for treating schizophrenia

Vanderbilt University has signed separate licensing and research collaboration agreements with Lundbeck, a global pharmaceutical company based in Denmark, to develop a novel approach for treating schizophrenia.

9 Jan 2018

Key synaptic proteins could be targets for early interventions in patients with dementias

One of the most intriguing properties of the brain is its means to undergo synaptic plasticity which represents the basis for learning and memory, abilities that severely decline in the case of a dementia.

9 Jan 2018

Regeneron forms consortium to accelerate largest widely-available human sequencing resource

By the end of 2019, Regeneron plans to sequence the exomes of all 500,000 people within the UK Biobank resource, all with associated health records, creating an unprecedented resource linking human genetic variations to human biology and disease.

9 Jan 2018

Researchers develop drug that supports cellular traffic jam theory in ALS/FTD

Neurodegeneration in ALS/FTD may be caused by TDP-43 aggregation in the cytoplasm, causing cellular traffic jams. The trial drug can sequester TDP-43.

9 Jan 2018

Her sister’s keeper: Caring for a sibling with mental illness

When sisters Jean and Ruby were growing up in Harlem, they invented a game of make-believe called "Eartha." The little girls would put on their prettiest dresses and shiniest shoes and sit down to tea as grown-up ladies. They discussed details of their hoped-for husbands and children, and all the exciting things they would do together.

9 Jan 2018

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Study reveals how devastating mitochondrial diseases strike families without any previous history

Mitochondrial impairment may actually protect the brain in Parkinson's disease, study shows

Whole of Britain to be put on a diet plan come March

U.S. FDA approves first drug for patients with germline BRCA-mutated metastatic breast cancer

Researchers use novel PET tracer to assess myelin damage in mouse models of MS

Study finds overall pattern of commonality between Huntington's and Parkinson's

Worsening of anxiety symptoms may be early indicator of Alzheimer's disease

Novel polygenic hazard score captures age variations of aggressive prostate cancer

Insilico Medicine develops new deep-learning based hematological human aging clock

For elder health, trips to the ER are often a tipping point

Pfizer to stop Alzheimer’s and Parkinson’s disease research

Salk scientists identify molecular target of experimental Alzheimer’s drug

Alzheimer’s Research UK calls on pharma to continue supporting dementia research

General anesthesia may be more complex in its workings than we know now

Researchers awarded grant to repurpose FDA-approved drugs for treating Alzheimer's patients

Vanderbilt and Lundbeck collaborate to develop novel approach for treating schizophrenia

Key synaptic proteins could be targets for early interventions in patients with dementias

Regeneron forms consortium to accelerate largest widely-available human sequencing resource

Researchers develop drug that supports cellular traffic jam theory in ALS/FTD

Her sister’s keeper: Caring for a sibling with mental illness

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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