Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Researchers find molecular mechanism that may be responsible for development of amyloidoses

A team of local researchers has proposed a molecular mechanism that may be responsible for the development of life-threatening diseases called amyloidoses. The best known of such diseases is Alzheimer's disease (AD), but there are many others that are receiving increased scrutiny, in part because of mounting evidence linking them to atherosclerosis and aging.

13 Nov 2015

Older adults with dementia make more frequent visits to emergency departments

Older adults with dementia are more frequent visitors to emergency departments, returning at higher rates and incurring greater costs than older adults without dementia, according to a new study from the Regenstrief Institute and the Indiana University Center for Aging Research. The study is one of the first to explore long-term patterns of healthcare use and mortality rates of elders with cognitive impairment who visit the emergency department.

13 Nov 2015

Experimental drug candidate aimed at combating Alzheimer's disease has anti-aging effects

Salk Institute researchers have found that an experimental drug candidate aimed at combating Alzheimer's disease has a host of unexpected anti-aging effects in animals.

13 Nov 2015

TGen: PPF drug could help treat patients with deadly brain cancer

In a significant breakthrough, the Translational Genomics Research Institute has identified a drug, propentofylline or PPF, that could help treat patients with deadly brain cancer.

13 Nov 2015

Reproductive history associated with cognitive impairment risk in postmenopausal women

Researchers led by Professor Jun-Fen Lin at Zhejiang Provincial Center for Disease Control and Prevention have found that reproductive history, an important modifier of estrogen exposure across women's lifetime, is associated with risk of cognitive impairment in postmenopausal women.

13 Nov 2015

Older populations in rural areas face special health care challenges

A new study of adults ages 85 or older has found that rural residents have significantly higher levels of chronic disease, take more medications, and die several years earlier than their urban counterparts.

13 Nov 2015

Mayo Clinic's Florida campus awarded NIH grant to identify vascular risk factors in aging and dementia

Mayo Clinic's Florida campus was awarded a $5.3 million grant from the National Institutes of Health to identify vascular risk factors in aging and dementia, and translate that knowledge into studying potential targets for treatment.

12 Nov 2015

Berkeley Lab scientists identify genetic factors that influence neurological disorders and body weight

Many neurological disorders, such as Parkinson's disease and Alzheimer's disease, are marked by impaired motor skills. In addition, growing evidence suggests there's a link between some neurodegenerative diseases and body weight. A recent NIH study, for example, found that adults who are obese or overweight at midlife may be at risk for earlier onset of Alzheimer's disease.

12 Nov 2015

Brain scans may predict possibility of recovering from coma

Brain scans of people in a coma may help predict who will regain consciousness, according to a study published in the November 11, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. The study looked at connections between areas of the brain that play a role in regulating consciousness.

12 Nov 2015

ApoE4-carrying men with Alzheimer's disease at risk of brain bleeds

A common genetic variation, ApoE4, linked to Alzheimer's disease greatly raises the likelihood of tiny brain bleeds in some men, scientists have found.

12 Nov 2015

Special orchestra boosts mood and confidence in patients with dementia

A special orchestra for people with dementia has helped boost their confidence and mood, according to a new research project.

11 Nov 2015

New progenitor cells differentiate into mature cell types, prevent risk of unwanted tumors

Human pluripotent stem cells (hPSC) can become any type of cell in the adult body, offering great potential in disease modeling, drug discovery and creating replacement cells for conditions ranging from cardiovascular to Alzheimer's disease.

11 Nov 2015

Eight myths and truths about Alzheimer's disease

Although Alzheimer's disease (AD) impacts more than five million Americans and 15 million caregivers year-round, the nation is especially focused on the disease this month as it observes "National Alzheimer's Disease and Awareness Month."

11 Nov 2015

Study finds high prevalence of dehydration in older people living in UK care homes

One in every five older people living in UK care homes has dehydration, suggesting that they are not drinking enough to keep themselves healthy.

11 Nov 2015

BU researcher gets prestigious fellowship to launch new project for people with dementia

A Bournemouth University researcher has been awarded a prestigious fellowship to launch a health and wellbeing project for people with dementia.

11 Nov 2015

Anavex reports safety and efficacy data of ANAVEX 2-73 Phase 2a trial in Alzheimer’s patients

On Saturday, investigators presented positive safety and cognitive efficacy data for ANAVEX 2-73, the Company’s lead investigational oral treatment for Alzheimer’s disease targeting sigma-1 and muscarinic receptors, which are believed to reduce protein misfolding including reduction of beta amyloid, tau protein and inflammation at the international CTAD 2015 conference in Barcelona, Spain.

11 Nov 2015

Intensive management of high blood pressure reduces rates of cardiovascular disease, lowers risk of death

Jackson T. Wright Jr., MD, PhD, and researchers from University Hospitals Case Medical Center presented new results from the Systolic Blood Pressure Intervention Trial (SPRINT) showing that in patients at high risk for cardiovascular events, targeting a systolic blood pressure of less than 120 mm Hg resulted in lower rates of fatal and non-fatal major events or death compared to targeting systolic blood pressure to the usually recommended target of less than 140 mm Hg.

10 Nov 2015

Possible reasons found for Alzheimer’s treatment failure

Agglutinated proteins in the brain, known as amyloid-β plaques, are a key characteristic of Alzheimer’s. One treatment option uses special antibodies to break down these plaques.

10 Nov 2015

Two studies explore potential new blood tests for Alzheimer's disease

There is increasing evidence that the brain changes of Alzheimer's disease begin decades before memory and thinking problems occur, prompting the need for better methods of early detection for this progressive, fatal brain disease. Consequently, there is a growing school of thought that the most effective future Alzheimer's drug therapies will be administered to those who are at high risk of the disease before cognitive symptoms appear.

10 Nov 2015

Age-related differences in brain health vary with fitness level in older adults

A new study shows that age-related differences in brain health - specifically the strength of connections between different regions of the brain - vary with fitness level in older adults. The findings suggest that greater cardiorespiratory fitness - a measure of aerobic endurance - relates to stronger brain connections and likely improves long-term brain function in aging populations.

6 Nov 2015

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Researchers find molecular mechanism that may be responsible for development of amyloidoses

Older adults with dementia make more frequent visits to emergency departments

Experimental drug candidate aimed at combating Alzheimer's disease has anti-aging effects

TGen: PPF drug could help treat patients with deadly brain cancer

Reproductive history associated with cognitive impairment risk in postmenopausal women

Older populations in rural areas face special health care challenges

Mayo Clinic's Florida campus awarded NIH grant to identify vascular risk factors in aging and dementia

Berkeley Lab scientists identify genetic factors that influence neurological disorders and body weight

Brain scans may predict possibility of recovering from coma

ApoE4-carrying men with Alzheimer's disease at risk of brain bleeds

Special orchestra boosts mood and confidence in patients with dementia

New progenitor cells differentiate into mature cell types, prevent risk of unwanted tumors

Eight myths and truths about Alzheimer's disease

Study finds high prevalence of dehydration in older people living in UK care homes

BU researcher gets prestigious fellowship to launch new project for people with dementia

Anavex reports safety and efficacy data of ANAVEX 2-73 Phase 2a trial in Alzheimer’s patients

Intensive management of high blood pressure reduces rates of cardiovascular disease, lowers risk of death

Possible reasons found for Alzheimer’s treatment failure

Two studies explore potential new blood tests for Alzheimer's disease

Age-related differences in brain health vary with fitness level in older adults

Innovation in neuroscience drug discovery - eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Innovation in neuroscience drug discovery - eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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