Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

First comprehensive maps and analyses of human epigenomes revealed

Two dozen scientific papers published online simultaneously on Feb. 18, 2015 present the first comprehensive maps and analyses of the epigenomes of a wide array of human cell and tissue types. Epigenomes are patterns of chemical annotations to the genome that determine whether, how, and when genes are activated.

18 Feb 2015

Actavis provides overview of standalone global pharmaceutical development pipeline

Actavis plc, during its Investor Meeting in New York, today provided a detailed look into its standalone global pharmaceutical development pipeline that supports the Company's long-term organic growth. The Company provided details regarding key development programs, including clinical data, development milestones and an overview of potential market opportunities, as well as an updated look at Actavis' world-class generics pipeline, which continues to hold an industry-leading position in First-to-File opportunities in the U.S.

18 Feb 2015

Dutch doctors share views on euthanasia

Around one in three Dutch doctors would be prepared to help someone with early dementia, mental illness, or who is 'tired of living' to die, reveals a small survey published online in the Journal of Medical Ethics.

18 Feb 2015

Scientists identify role of tau-associated MAPT gene in development of Alzheimer's disease

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, has identified the microtubule-associated protein tau (MAPT) gene as increasing the risk for developing Alzheimer's disease (AD).

18 Feb 2015

RUDAS effectively assesses cognitive impairment in multicultural older populations

The ability to assess cognitive impairment in multicultural older populations will become more important as demographics change worldwide. A new study published in CMAJ (Canadian Medical Association Journal) reports that the Rowland Universal Dementia Assessment Scale (RUDAS) is particularly effective in multicultural populations where English is not a patient's first language.

18 Feb 2015

Researchers identify molecule that can block progression of Alzheimer's disease

A molecule that can block the progress of Alzheimer's disease at a crucial stage in its development has been identified by researchers in a new study, raising the prospect that more such molecules may now be found.

18 Feb 2015

Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

Scientists at Trinity College Dublin have uncovered a marvel molecule that blocks a key driver of inflammatory diseases. The finding could meet a major unmet clinical need by inspiring new non-invasive treatments for arthritis, multiple sclerosis and Muckle-Wells syndrome, among a myriad of other inflammatory diseases.

18 Feb 2015

UBMD physician discusses the dangers of hypothermia

The arctic cold snap affecting the Midwest and the Northeast this weekend should not be taken lightly, says David Holmes, MD, clinical associate professor of family medicine in the University at Buffalo School of Medicine and Biomedical Sciences.

17 Feb 2015

BHB compound produced during dieting blocks part of immune system involved in inflammatory disorders

Researchers at Yale School of Medicine have found that a compound produced by the body when dieting or fasting can block a part of the immune system involved in several inflammatory disorders such as type 2 diabetes, atherosclerosis, and Alzheimer's disease.

17 Feb 2015

Study shows amyloid formation may link type 2 diabetes and Alzheimer disease

The pathological process amyloidosis, in which misfolded proteins (amyloids) form insoluble fibril deposits, occurs in many diseases, including Alzheimer disease (AD) and type 2 diabetes mellitus (T2D).

17 Feb 2015

Study suggests introduction of specific NGF to prevent neuronal degradation in Alzheimer's patients

Scientists at Karolinska Institutet have evaluated a new Alzheimer's therapy in which the patients receive an implant that stimulates the growth of a certain type of nerve cell. The results, which are published in the scientific journal Alzheimer's & Dementia, suggest that the introduction of a nerve growth factor can prevent neuronal degradation in Alzheimer's patients.

16 Feb 2015

TSRI scientists discover novel mechanism involved in Alzheimer's, Parkinson's and ALS

Scientists from the Florida campus of The Scripps Research Institute have for the first time discovered a killing mechanism that could underpin a range of the most intractable neurodegenerative diseases such as Alzheimer's, Parkinson's and ALS.

16 Feb 2015

$Eisai announces FDA approval of LENVIMA (lenvatinib) for treatment of RAI-refractory DTC$

Eisai announces FDA approval of LENVIMA (lenvatinib) for treatment of RAI-refractory DTC

Eisai Inc. announced today that the U.S. Food and Drug Administration approved the company's receptor tyrosine kinase inhibitor LENVIMA (lenvatinib) for the treatment of locally recurrent or metastatic, progressive, radioactive iodine-refractory differentiated thyroid cancer (RAI-R DTC).

13 Feb 2015

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

The new study, published recently in the journal Brain, revealed the mechanism of toxicity of a misfolded form of the protein that underlies prion diseases, such as bovine spongiform encephalopathy (“mad cow disease”) and its human equivalent, Creutzfeldt-Jakob disease.

13 Feb 2015

Stem cell transplants more effective than mitoxantrone drug for people with severe multiple sclerosis

Stem cell transplants may be more effective than the drug mitoxantrone for people with severe cases of multiple sclerosis (MS), according to a new study published in the February 11, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Feb 2015

RAB3GAP complex plays important role in autophagy

Neurodegenerative disorders such as Alzheimer's disease are typically characterized by protein deposits in the brain. These are comprised of defective, insoluble proteins which no longer fulfill their function and which cells are unable to break down. The work group headed by Professor Christian Behl of the Institute of Pathobiochemistry of the University Medical Center of Johannes Gutenberg University Mainz has determined the RAB3GAP complex as a novel factor that influences the efficient degradation of proteins.

12 Feb 2015

Children exposed to air pollution are at increased risk for brain inflammation, neurodegenerative changes

City smog lowers children's IQ. This is among findings from a recent University of Montana study that found children living in cities with significant air pollution are at an increased risk for detrimental impacts to the brain, including short-term memory loss and lower IQ.

12 Feb 2015

USF researchers awarded grant to test new drug for age-related hearing loss

A successful treatment for age-related hearing loss (ARHL) is a step closer to reality, thanks to a group of researchers from the University of South Florida. The research team comprised of faculty and students has been awarded $400,000 by Autifony Therapeutics, Ltd, a company based in the United Kingdom, to test a new drug the company developed for ARHL.

12 Feb 2015

Transition Therapeutics commences underwritten public offering of common shares

Transition Therapeutics Inc. announced today that it has commenced an underwritten public offering of its common shares.

12 Feb 2015

New article assesses 40 years of intensive effort to improve end-of-life care

After four decades of work - first on patients' rights, then on family and caregiving relationships, and most recently on systemic reform -- we now know that it will take additional efforts in all three areas to improve care at the end of life, concludes an article in the New England Journal of Medicine.

11 Feb 2015

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

First comprehensive maps and analyses of human epigenomes revealed

Actavis provides overview of standalone global pharmaceutical development pipeline

Dutch doctors share views on euthanasia

Scientists identify role of tau-associated MAPT gene in development of Alzheimer's disease

RUDAS effectively assesses cognitive impairment in multicultural older populations

Researchers identify molecule that can block progression of Alzheimer's disease

Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

UBMD physician discusses the dangers of hypothermia

BHB compound produced during dieting blocks part of immune system involved in inflammatory disorders

Study shows amyloid formation may link type 2 diabetes and Alzheimer disease

Study suggests introduction of specific NGF to prevent neuronal degradation in Alzheimer's patients

TSRI scientists discover novel mechanism involved in Alzheimer's, Parkinson's and ALS

Eisai announces FDA approval of LENVIMA (lenvatinib) for treatment of RAI-refractory DTC

'Mad Cow' discovery points to possible neuron killing mechanism behind alzheimer’s and parkinson’s diseases

Stem cell transplants more effective than mitoxantrone drug for people with severe multiple sclerosis

RAB3GAP complex plays important role in autophagy

Children exposed to air pollution are at increased risk for brain inflammation, neurodegenerative changes

USF researchers awarded grant to test new drug for age-related hearing loss

Transition Therapeutics commences underwritten public offering of common shares

New article assesses 40 years of intensive effort to improve end-of-life care

Innovation in neuroscience drug discovery - eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Innovation in neuroscience drug discovery - eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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