Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Researchers uncover mechanism by which anti-inflammatory processes may cause Alzheimer's

Inflammation has long been studied in Alzheimer's, but in a counterintuitive finding reported in a new paper, University of Florida researchers have uncovered the mechanism by which anti-inflammatory processes may trigger the disease.

23 Jan 2015

USC neuroscientists find potential prevention for Alzheimer's disease

University of Southern California neuroscientists may have unlocked another puzzle to preventing risks that can lead to Alzheimer's disease. Researchers at Keck Medicine of USC used high-resolution imaging of the living human brain to show for the first time that the brain's protective blood barrier becomes leaky with age, starting at the hippocampus, a critical learning and memory center that is damaged by Alzheimer's disease.

22 Jan 2015

Heptares Therapeutics, AstraZeneca report significant progress in drug discovery collaboration

Heptares Therapeutics, the clinical-stage GPCR structure-guided drug discovery and development company, announces significant progress in its drug discovery collaboration with AstraZeneca.

22 Jan 2015

Study: Prostate cancer drug stabilizes memory loss for a year in women with Alzheimer's disease

Women with Alzheimer's disease showed stable cognition for a year when a drug that is more commonly used to treat advanced prostate cancer was added to their drug regimen, according to a new study from researchers at the University of Wisconsin-Madison.

22 Jan 2015

ENIGMA scientists discover eight genetic mutations that may erode or boost brain tissue

In the largest collaborative study of the brain to date, researchers from the Keck School of Medicine of the University of Southern California led a global consortium of 190 institutions to identify eight common genetic mutations that appear to age the brain an average of three years. The discovery could lead to targeted therapies and interventions for Alzheimer's disease, autism and other neurological conditions.

22 Jan 2015

Microscopic spheres of calcium phosphate linked to AMD development

Microscopic spheres of calcium phosphate have been linked to the development of age-related macular degeneration (AMD), a major cause of blindness, by UCL-led research.

21 Jan 2015

Alzheimer's drug Aricept (donepezil) linked to serious side effects

New warnings have been added to the prescribing information for the Alzheimer's drug Aricept (donepezil) advising of the risk of two rare but potentially serious conditions: muscle breakdown (rhabdomyolysis) and a neurological disorder called neuroleptic malignant syndrome (NMS).

21 Jan 2015

Walnuts may improve cognitive function

Eating walnuts may improve performance on cognitive function tests, including those for memory, concentration and information processing speed according to new research from the David Geffen School of Medicine at The University of California, Los Angeles, led by Dr. Lenore Arab. Cognitive function was consistently greater in adult participants that consumed walnuts, regardless of age, gender or ethnicity.

21 Jan 2015

MU researcher develops intervention to help older adults gradually adjust to hearing aids

When individuals wear their hearing aids for the first time, they are flooded with sounds they have not heard in months or years; yet, previous research has shown that not all new sounds are welcomed. Ambient noises such as air conditioners, wind and background conversations can be painful, irritating and difficult to ignore, causing some individuals to stop using their hearing aids right away.

21 Jan 2015

Joining a walking group helps boost overall health

Joining a walking group is one of the best and easiest ways to boost overall health, with virtually no side effects, suggests an analysis of the available evidence, published online in the British Journal of Sports Medicine.

20 Jan 2015

Abnormal attachment of sugar to BACE1 enzyme leads to formation of Aβ plaques in the brain

Researchers at the RIKEN-Max Planck Joint Research Center in Japan have demonstrated that hallmark symptoms of Alzheimer's disease can be reduced when sugars are prevented from binding to one of the key enzymes implicated in the disease. The new findings, reported in EMBO Molecular Medicine, show that abnormal attachment of a particular sugar to the enzyme BACE1 is a critical factor leading to the formation of Aβ plaques in the brain, and that plaques were reduced and cognitive performance improved when this action was prevented in mice through loss of the enzyme GnT-III.

17 Jan 2015

MRIGlobal awarded $54 million NIH contract to provide support for drug development

MRIGlobal today announced that it has been awarded a $54 million, 10-year program from the National Institute of Neurological Disorders and Stroke to provide support for the development and manufacturing of drug candidates for ultimate use in human clinical trials.

15 Jan 2015

Better Eyes for Longer Life without Alzheimer's research project opens to everyone

The Alzheimer's Association puts a fine point on the truism that the risk of developing Alzheimer's disease or some other form of cognitive impairment increases with age: (They expect that) 7 million of those who reach 85 by 2050 will have Alzheimer's disease (AD).

15 Jan 2015

Vascular and Alzheimer's-related brain abnormalities cause dementia in older people

A growing body of research suggests that the most common cause of dementia in older people is a mix of vascular and Alzheimer's-related brain abnormalities, and that approximately half of people who die with Alzheimer's also have evidence of strokes in their brains. Furthermore, when strokes and hallmark Alzheimer's plaques and tangles are combined, it increases a person's likelihood of experiencing dementia.

15 Jan 2015

Venom of cone snails provides leads for possible treatment of cancer, addiction

While considered a delicacy in some parts of the world, snails have found a more intriguing use to scientists and the medical profession offering a plethora of research possibilities. Cone snails are marine mollusks, just as conch, octopi and squid, but they capture their prey using venom.

15 Jan 2015

Study: Depression, behavioral changes may occur in Alzheimer's disease before memory declines

Depression and behavioral changes may occur before memory declines in people who will go on to develop Alzheimer's disease, according to new research at Washington University School of Medicine in St. Louis.

14 Jan 2015

Man-made insulin nasal spray may improve memory in adults with Alzheimer's-related dementia

A man-made form of insulin delivered by nasal spray may improve working memory and other mental capabilities in adults with mild cognitive impairment and Alzheimer's disease dementia, according to a pilot study led by researchers at Wake Forest Baptist Medical Center.

9 Jan 2015

American Migraine Foundation plans to create Migraine Patient Registry and Biorepository

Migraine affects 36 million Americans, can have a major impact on patients' quality of life, and even on their relationships. The World Health Organization estimates that migraine is the third most prevalent medical disorder in the world, the 4th most disabling among women and the 7th most disabling overall.

8 Jan 2015

Research findings could lead to new drug design for neurological diseases

A new intermediate step and unexpected enzymatic activity in a metabolic pathway in the body, which could lead to new drug design for psychiatric and neurodegenerative diseases, has been discovered by researchers at Georgia State University.

8 Jan 2015

Study: Synthetic triglyceride oil may provide hope for people with Huntington's disease

An early study suggests that a synthetic triglyceride oil called triheptanoin may provide hope for people with Huntington's disease. The study is published in the January 7, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Jan 2015

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Researchers uncover mechanism by which anti-inflammatory processes may cause Alzheimer's

USC neuroscientists find potential prevention for Alzheimer's disease

Heptares Therapeutics, AstraZeneca report significant progress in drug discovery collaboration

Study: Prostate cancer drug stabilizes memory loss for a year in women with Alzheimer's disease

ENIGMA scientists discover eight genetic mutations that may erode or boost brain tissue

Microscopic spheres of calcium phosphate linked to AMD development

Alzheimer's drug Aricept (donepezil) linked to serious side effects

Walnuts may improve cognitive function

MU researcher develops intervention to help older adults gradually adjust to hearing aids

Joining a walking group helps boost overall health

Abnormal attachment of sugar to BACE1 enzyme leads to formation of Aβ plaques in the brain

MRIGlobal awarded $54 million NIH contract to provide support for drug development

Better Eyes for Longer Life without Alzheimer's research project opens to everyone

Vascular and Alzheimer's-related brain abnormalities cause dementia in older people

Venom of cone snails provides leads for possible treatment of cancer, addiction

Study: Depression, behavioral changes may occur in Alzheimer's disease before memory declines

Man-made insulin nasal spray may improve memory in adults with Alzheimer's-related dementia

American Migraine Foundation plans to create Migraine Patient Registry and Biorepository

Research findings could lead to new drug design for neurological diseases

Study: Synthetic triglyceride oil may provide hope for people with Huntington's disease

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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