Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Scientists discover CD2AP protein that plays key role in nervous system

University of Louisville researchers have discovered that a protein previously known for its role in kidney function also plays a significant role in the nervous system. In an article featured in the April 13 issue of the Journal of Neuroscience, they show that the adaptor protein CD2AP is a key player in a type of neural growth known as collateral sprouting.

21 Apr 2016

Almost half of all long-stay nursing home residents visit ED every year regardless of cognitive status

A new study from the Indiana University Center for Aging Research and the Regenstrief Institute has found that almost half of all long-stay nursing home residents experience at least one transfer to an Emergency Department over the course of a year regardless of their cognitive status. While a high percentage of long-stay nursing home residents were sent to the ED, only about a third of these individuals were subsequently admitted to the hospital.

20 Apr 2016

Researchers evaluate TBI-associated risk factors in older adults

Traumatic brain injury (TBI), a leading cause of death and disability, has become so common in recent times that it has been called a "silent epidemic." And because older adults are more likely to suffer TBI, have worse outcomes, and are less likely to survive their injury than younger adults, older adults are considered a "silent population" within this epidemic.

20 Apr 2016

Researchers examine effectiveness of antipsychotic drugs to prevent or treat delirium

In a study published in the Journal of the American Geriatrics Society, researchers examined whether or not antipsychotic drugs, which are sometimes used to prevent or treat delirium, are effective.

20 Apr 2016

Study investigates usefulness of plasma levels as biomarker for AD

A Centre for Healthy Brain Ageing paper published in Current Alzheimer Research presents the first detailed study of the relationship between plasma levels of two amyloid beta peptides (Aβ1-40 and Aβ1-42), brain volumetrics (measures studying the size of brain, which shrinks with Alzheimer's disease) and cognitive performance in an investigation of the usefulness of plasma levels as a biomarker for Alzheimer's disease (AD).

19 Apr 2016

AAN’s updated guideline on botulinum toxin use covers four neurologic disorders

The American Academy of Neurology has updated its 2008 guidelines on the use of botulinum toxin for spasticity, cervical dystonia, blepharospasm and migraine headache, based on recent research.

19 Apr 2016

MR may detect earliest Alzheimer's brain changes

Levels of the brain metabolite and neuroinflammation marker myo-inositol are elevated in asymptomatic patients with abnormal Alzheimer's disease (AD) biomarkers, say researchers. As repo ...

18 Apr 2016

Study shows children with rare eye disease have greatest benefit from gene therapy

Scientists at Oregon Health & Science University's Casey Eye Institute and Baylor College of Medicine's Cullen Eye Institute published findings from a two-year Phase I clinical trial in the journal Ophthalmology, which showed that children had the greatest benefit from gene therapy for treatment of Leber congenital amaurosis (LCA) or severe early childhood onset retinal degeneration (SECORD).

18 Apr 2016

Georgetown researchers report first case of Alzheimer's disease diagnosed in HIV-positive individual

Georgetown University researchers are reporting the first case of Alzheimer's disease diagnosed in an HIV-positive individual. The finding in a 71-year-old man triggers a realization about HIV survivors now reaching the age when Alzheimer's risk begins to escalate.

18 Apr 2016

Scientists identify unique memory suppressor gene that could provide clues for new Alzheimer’s disease treatments

While research has identified hundreds of genes required for normal memory formation, genes that suppress memory are of special interest because they offer insights into how the brain prioritizes and manages all of the information, including memories, that it takes in every day.

18 Apr 2016

Alzheimer's preclinical staging criteria supported

The Alzheimer's disease preclinical staging criteria proposed by the National Institute on Aging and the Alzheimer's Association appear to be valid over more than a decade of follow-up, say researchers.

15 Apr 2016

PITRM1 protein may be involved in development of Alzheimer's disease

University of Bergen researchers have found a protein that could hold the key to understanding how Alzheimer's disease develops.

14 Apr 2016

National plan outlines milestones, strategies for Alzheimer's patient care and caregiver support

The National Alzheimer's Project Act (NAPA) was signed into law in 2011. Over the past five years milestones have been identified to meet the plan's biomedical research goal. However, similar milestones have not been created for the goals on patient care and caregiver support.

13 Apr 2016

NYU Stern innovation expert uncovers new link between diabetes and Alzheimer's disease

In a new paper published by The Journal of Alzheimer's Disease, Professor Melissa Schilling, a strategy and innovation expert at the NYU Stern School of Business, uncovers a surprising new connection between diabetes and Alzheimer's disease: hyperinsulinemia, which is most often caused by prediabetes, early or undiagnosed diabetes, or obesity, is responsible for almost half of all cases of Alzheimer's disease.

13 Apr 2016

Common antihistamine may partially reverse damage to visual system in multiple sclerosis patients

A common antihistamine used to treat symptoms of allergies and the common cold, called clemastine fumarate, partially reversed damage to the visual system in people with multiple sclerosis (MS) in a preliminary study released today that will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

13 Apr 2016

Rush awarded $14.5 million NIA grant to study effects of MIND diet on Alzheimer's disease

Can a particular diet prevent Alzheimer's disease? The National Institute of Aging has invested heavily in Rush University Medical Center to try to find out.

13 Apr 2016

Biopsy of submandibular gland can help identify pathology of Parkinson's disease, dementia with Lewy bodies

Accurate diagnosis of Parkinson's disease, and the related disease "dementia with Lewy bodies," can be difficult in the early stages of both conditions. While brain biopsies can be more accurate, the risk of complications has been considered too high. New research published in the Journal of Parkinson's Disease indicates that a biopsy of the submandibular gland can help identify the same pathology that is seen in the brain, providing some of the increased accuracy of brain biopsy, but not the increased risk.

12 Apr 2016

Six newly identified proteins may help potentially unlock new insights into aging-related diseases

A group of six newly discovered proteins may help to divulge secrets of how we age, potentially unlocking new insights into diabetes, Alzheimer's, cancer, and other aging-related diseases.

12 Apr 2016

Abnormally active Rab5 protein leads to early development of neurodegenerative disease

Writing in the April 11 issue of The Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells are linked to axonal dysfunction and degeneration of neurons in Alzheimer's disease (AD) and Down syndrome (DS).

12 Apr 2016

Glial cells can modulate specific nerve endings in the brain, find Rockefeller scientists

More than half of our brains are made up of glial cells, which wrap around nerve fibers and insulate them--similarly to how the plastic casing of an electric cable insulates the copper wire within--allowing electrical and chemical impulses to travel faster.

12 Apr 2016

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Scientists discover CD2AP protein that plays key role in nervous system

Almost half of all long-stay nursing home residents visit ED every year regardless of cognitive status

Researchers evaluate TBI-associated risk factors in older adults

Researchers examine effectiveness of antipsychotic drugs to prevent or treat delirium

Study investigates usefulness of plasma levels as biomarker for AD

AAN’s updated guideline on botulinum toxin use covers four neurologic disorders

MR may detect earliest Alzheimer's brain changes

Study shows children with rare eye disease have greatest benefit from gene therapy

Georgetown researchers report first case of Alzheimer's disease diagnosed in HIV-positive individual

Scientists identify unique memory suppressor gene that could provide clues for new Alzheimer’s disease treatments

Alzheimer's preclinical staging criteria supported

PITRM1 protein may be involved in development of Alzheimer's disease

National plan outlines milestones, strategies for Alzheimer's patient care and caregiver support

NYU Stern innovation expert uncovers new link between diabetes and Alzheimer's disease

Common antihistamine may partially reverse damage to visual system in multiple sclerosis patients

Rush awarded $14.5 million NIA grant to study effects of MIND diet on Alzheimer's disease

Biopsy of submandibular gland can help identify pathology of Parkinson's disease, dementia with Lewy bodies

Six newly identified proteins may help potentially unlock new insights into aging-related diseases

Abnormally active Rab5 protein leads to early development of neurodegenerative disease

Glial cells can modulate specific nerve endings in the brain, find Rockefeller scientists

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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