Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Ultrasound can modulate brain activity to heighten sensory perception in humans

Whales, bats, and even praying mantises use ultrasound as a sensory guidance system - and now a new study has found that ultrasound can modulate brain activity to heighten sensory perception in humans.

13 Jan 2014

At-home paper test can help spot early symptoms of cognitive issues

The Self-Administered Gerocognitive Examination (SAGE test), which takes less than 15 minutes to complete, is a reliable tool for evaluating cognitive abilities. Findings by researchers at The Ohio State University Wexner Medical Center confirming the feasibility and efficiency of the tool for community screening large numbers of people are published in the January issue of The Journal of Neuropsychiatry and Clinical Neurosciences.

13 Jan 2014

Researchers discover two genetic mutations associated with Familial Alzheimer's Disease

New research, led by Rensselaer Polytechnic Institute researcher Chunyu Wang, has solved one mystery in the development of Familial Alzheimer's Disease (FAD), a genetic variant of the disease that affects a small fraction of the Alzheimer's population. In a paper published online January 6 in the journal Nature Communications, Wang and his team follow the trail of two genetic mutations - V44M and V44A - known to cause FAD, and show how the mutations lead to biochemical changes long linked to the disease.

13 Jan 2014

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Today the scientific journal Neuron published results on the Roche-designed Brain Shuttle technology that efficiently transfers investigational antibodies from the blood through the blood-brain barrier (BBB) into the brain in preclinical models.

10 Jan 2014

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

Biogen Idec and Sangamo BioSciences, Inc. announced today an exclusive worldwide collaboration and license agreement focused on the development of therapeutics for hemoglobinopathies, inherited conditions that result from the abnormal structure or underproduction of hemoglobin.

9 Jan 2014

NYSCF and ISMMS scientists successfully generate stem cell model of familial Alzheimer's disease

Scientists at The New York Stem Cell Foundation Research Institute in collaboration with scientists at the Icahn School of Medicine at Mount Sinai successfully generated a stem cell model of familial Alzheimer's disease.

8 Jan 2014

Epilepsy drug taken during pregnancy not linked with development problems for preschoolers

A new study finds that the epilepsy drug levetiracetam appears not to be associated with thinking, movement and language problems for preschool children born to mothers who took the drug during pregnancy, although the drug valproate was associated with some difficulties in preschoolers.

8 Jan 2014

Slower decline for patients with PARKIN-associated PD

Cognitive and motor decline may be slower in patients with early-onset Parkinson’s disease if they have PARKIN mutations, suggests an analysis of the Consortium on Risk for Early-Onset PD study.

8 Jan 2014

Dementia detracts from PD patients’ life expectancy

Patients with Parkinson’s disease have an increased risk for mortality, especially if they have dementia, a meta-analysis confirms.

8 Jan 2014

Study links racism-related factors and biological aging among African American men

A new study reveals that racism may impact aging at the cellular level. Researchers found signs of accelerated aging in African American men, ages reporting high levels of racial discrimination and who had internalized anti-Black attitudes.

8 Jan 2014

Scientists believe that new links between brain cells help encode new memories and skills

In adults, some brain regions retain a "childlike" ability to establish new connections, potentially contributing to our ability to learn new skills and form new memories as we age, according to new research from Washington University School of Medicine in St. Louis and the Allen Institute for Brain Science in Seattle.

8 Jan 2014

Study shows ability to make living human cells from biobanked brain tissue of Alzheimer's patients

Scientists at The New York Stem Cell Foundation (NYSCF) Research Institute, working in collaboration with scientists from Columbia University Medical Center (CUMC), for the first time generated induced pluripotent stem (iPS) cells lines from non-cryoprotected brain tissue of patients with Alzheimer's disease.

7 Jan 2014

Elderly people with high serum vitamin E levels less likely to suffer from memory disorders

Elderly people with high serum vitamin E levels are less likely to suffer from memory disorders than their peers with lower levels, according to a study published recently in Experimental Gerontology.

7 Jan 2014

50% of Canadians with dementia are not diagnosed early enough

As many as 50 per cent of Canadians with dementia are not diagnosed early enough,* losing precious time when care and support can make a tremendous difference in their quality of life and avert unnecessary crises for their families.

7 Jan 2014

TauRx Therapeutics adds new research centers across U.S. for Alzheimer’s clinical trials

TauRx Therapeutics Ltd, a clinical-stage biopharmaceutical company developing a novel treatment for Alzheimer's disease, has expanded its international clinical trials by adding new research centers across the U.S.

6 Jan 2014

Parkinson's disease patients from lower socioeconomic status less likely to receive DBS

Among Parkinson's disease (PD) patients, female, black, Asian and patients are substantially less likely to receive proven deep brain stimulation (DBS) surgery to improve tremors and motor symptoms, according to a new report by a Perelman School of Medicine at the University of Pennsylvania researcher who identified considerable disparities among Medicare recipients receiving DBS for Parkinson's disease.

5 Jan 2014

AstraZeneca to take over Probiodrug's CDK9 inhibitor program

Probiodrug AG announced today the transfer of its experimental cyclin-dependent kinase 9 inhibitor program to AstraZeneca. The transaction includes the sale to AstraZeneca of a lead molecule and back-up compounds with the associated intellectual property. CDK9, which has been implicated in the transcriptional regulation of genes involved in proliferation and inflammation, is a promising target for the treatment of both cancer and inflammatory diseases.

3 Jan 2014

Shingles may increase risk of stroke in later life, study finds

Having shingles may increase the risk of having a stroke years later, according to research published in the January 2, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

2 Jan 2014

Study: Alpha tocepherol, fat-soluble vitamin E, antioxidant may slow functional decline in AD patients

Difficulty with activities of daily living often affect Alzheimer's patients, which is estimated to affect as many as 5.1 million Americans. These issues are among the most taxing burdens of the disease for caregivers, which total about 5.4 million family members and friends.

1 Jan 2014

Researchers find inhibition of basic cellular process that contributes to schizophrenia

Surprisingly little is known about schizophrenia. It was only recognized as a medical condition in the past few decades, and its exact causes remain unclear. Since there is no objective test for schizophrenia, its diagnosis is based on an assortment of reported symptoms.

30 Dec 2013

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Ultrasound can modulate brain activity to heighten sensory perception in humans

At-home paper test can help spot early symptoms of cognitive issues

Researchers discover two genetic mutations associated with Familial Alzheimer's Disease

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

NYSCF and ISMMS scientists successfully generate stem cell model of familial Alzheimer's disease

Epilepsy drug taken during pregnancy not linked with development problems for preschoolers

Slower decline for patients with PARKIN-associated PD

Dementia detracts from PD patients’ life expectancy

Study links racism-related factors and biological aging among African American men

Scientists believe that new links between brain cells help encode new memories and skills

Study shows ability to make living human cells from biobanked brain tissue of Alzheimer's patients

Elderly people with high serum vitamin E levels less likely to suffer from memory disorders

50% of Canadians with dementia are not diagnosed early enough

TauRx Therapeutics adds new research centers across U.S. for Alzheimer’s clinical trials

Parkinson's disease patients from lower socioeconomic status less likely to receive DBS

AstraZeneca to take over Probiodrug's CDK9 inhibitor program

Shingles may increase risk of stroke in later life, study finds

Study: Alpha tocepherol, fat-soluble vitamin E, antioxidant may slow functional decline in AD patients

Researchers find inhibition of basic cellular process that contributes to schizophrenia

Innovation in neuroscience drug discovery - eBook eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Innovation in neuroscience drug discovery - eBook eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

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