Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Study: Cholesterol levels linked to early signs of Alzheimer's disease in the brain

High levels of "good" cholesterol and low levels of "bad" cholesterol are correlated with lower levels of the amyloid plaque deposition in the brain that is a hallmark of Alzheimer's disease, in a pattern that mirrors the relationship between good and bad cholesterol in cardiovascular disease, UC Davis researchers have found.

30 Dec 2013

MitoQ antioxidant reverses MS-like disease in animal

Researchers at Oregon Health & Science University have discovered that an antioxidant designed more than a dozen years ago to fight damage within human cells significantly helps symptoms in mice that have a multiple sclerosis-like disease.

27 Dec 2013

Three foods can help prevent Alzheimer's disease

The number of Americans with Alzheimer's is projected to triple by 2050. While there isn't a cure for Alzheimer's, certain lifestyle changes can help prevent cognitive decline.

27 Dec 2013

Concussion involving momentary loss of consciousness may be related to buildup of Alzheimer's

A new study suggests that a history of concussion involving at least a momentary loss of consciousness may be related to the buildup of Alzheimer's-associated plaques in the brain.

27 Dec 2013

Cell transplantation, gene therapy combination to open new therapeutic avenues for Alzheimer's disease

In a recent study published in the Neural Regeneration Research (Vol. 8, No. 33, 2013), Prof. Feng Li and team from Zhongshan School of Medicine, Sun Yat-sen University in China, synthesized a 19-nt oligonucleotide targeting BACE1, the key enzyme in amyloid beta protein (Aβ) production, and introduced it into the pSilenCircle vector to construct a short hairpin (shRNA) expression plasmid against the BACE1 gene.

24 Dec 2013

Researchers report new gene delivery method that targets tumor blood vessels

Working in mice, researchers at Washington University School of Medicine in St. Louis report developing a gene delivery method long sought in the field of gene therapy: a deactivated virus carrying a gene of interest that can be injected into the bloodstream and make its way to the right cells.

24 Dec 2013

CUMC researchers clarify three fundamental issues about Alzheimer's disease

Using high-resolution functional MRI imaging in patients with Alzheimer's disease and in mouse models of the disease, Columbia University Medical Center researchers have clarified three fundamental issues about Alzheimer's: where it starts, why it starts there, and how it spreads. In addition to advancing understanding of Alzheimer's, the findings could improve early detection of the disease, when drugs may be most effective.

22 Dec 2013

Most dementia people living at home have multiple unmet health and welfare needs

Most people with dementia who live at home have multiple unmet health and welfare needs, any number of which could jeopardize their ability to remain home for as long as they desire, new Johns Hopkins research suggests.

20 Dec 2013

Deep brain stimulation may have beneficial effect on driving ability for Parkinson's disease patients

Deep brain stimulation may have a beneficial effect on driving ability for people with Parkinson's disease, according to a new study published in the December 18, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. Deep brain stimulation uses a surgical implant similar to a pacemaker to send electrical impulses to the brain.

19 Dec 2013

Primary cilia play key role in stem cell differentiation

Researchers at Queen Mary University of London have shown for the first time that the specialised role stem cells go on to perform is controlled by primary cilia -tiny hair-like structures protruding from a cell.

18 Dec 2013

Nonsurgical treatment of periodontal disease does not improve glycemic control in patients with diabetes

A recent study published in the Journal of the American Medical Association (JAMA) found that nonsurgical treatment of periodontal disease does not improve glycemic control in patients with type 2 diabetes.

18 Dec 2013

Moderate drinking may bolster our immune system and help fight off infection: Study

Medical science has known for years that people who drink moderate amounts of alcohol actually have a reduced risk of death. In general, they are healthier and have better cardiovascular function that those who don't drink alcohol at all.

17 Dec 2013

Researchers use ATX-Red AR-2 as new imaging agent to illuminate tumors

Researchers from Echelon Biosciences, Inc. and collaborators from the University of Utah report the use of ATX-Red AR-2 as a new imaging agent that effectively illuminates tumors.

17 Dec 2013

Researchers discover direct evidence of genetic overlap between cognitive ability and schizophrenia

Investigators at The Feinstein Institute for Medical Research have discovered for the first time, direct evidence of a genetic overlap between schizophrenia and general cognitive ability. The findings are published online in Molecular Psychiatry.

17 Dec 2013

European team experts to explore role of neighborhood in everyday lives of people with dementia

A European team of experts led by The University of Manchester will explore, investigate and evaluate the role of the neighbourhood in the everyday lives of people with dementia and their families in a new research project announced during the G8 dementia summit today (11 December).

17 Dec 2013

New regulations could improve vets' access to care for some traumatic brain injuries

The Department of Veterans Affairs has approved new regulations to make it easier for veterans to receive health care and compensation for certain illnesses, including Parkinsonism, dementia, and depression, which have been linked to traumatic brain injury

17 Dec 2013

Research findings point to possible new strategy for treating ALS

Amyotrophic lateral sclerosis, better known as Lou Gehrig's disease, is a devastating illness that gradually robs sufferers of muscle strength and eventually causes a lethal, full-body paralysis. The only drug available to treat the disease extends life spans by a meager three months on average.

17 Dec 2013

New study aims to better understand brain aging and AD in adults with Down syndrome

To many, Down syndrome is a childhood condition. But improved health care means that individuals with DS now routinely reach age 50 or 60 years of age, sometimes beyond. However, if they live long enough, people with Down syndrome are almost certain to develop Alzheimer's disease.

17 Dec 2013

Targacept reports top-line results from TC-5619 Phase 2b trial for negative symptoms in schizophrenia

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today announced top-line results from a Phase 2b clinical trial of TC-5619 as an augmentation therapy for the treatment of negative symptoms of schizophrenia.

17 Dec 2013

Researchers identify first biomarker that appears to be associated with duration of delirium

Researchers from the Regenstrief Institute and the Indiana University Center for Aging Research have identified the first biomarker that appears to be linked to the duration of delirium.

16 Dec 2013

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Study: Cholesterol levels linked to early signs of Alzheimer's disease in the brain

MitoQ antioxidant reverses MS-like disease in animal

Three foods can help prevent Alzheimer's disease

Concussion involving momentary loss of consciousness may be related to buildup of Alzheimer's

Cell transplantation, gene therapy combination to open new therapeutic avenues for Alzheimer's disease

Researchers report new gene delivery method that targets tumor blood vessels

CUMC researchers clarify three fundamental issues about Alzheimer's disease

Most dementia people living at home have multiple unmet health and welfare needs

Deep brain stimulation may have beneficial effect on driving ability for Parkinson's disease patients

Primary cilia play key role in stem cell differentiation

Nonsurgical treatment of periodontal disease does not improve glycemic control in patients with diabetes

Moderate drinking may bolster our immune system and help fight off infection: Study

Researchers use ATX-Red AR-2 as new imaging agent to illuminate tumors

Researchers discover direct evidence of genetic overlap between cognitive ability and schizophrenia

European team experts to explore role of neighborhood in everyday lives of people with dementia

New regulations could improve vets' access to care for some traumatic brain injuries

Research findings point to possible new strategy for treating ALS

New study aims to better understand brain aging and AD in adults with Down syndrome

Targacept reports top-line results from TC-5619 Phase 2b trial for negative symptoms in schizophrenia

Researchers identify first biomarker that appears to be associated with duration of delirium

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

How can super-resolution technology help study neurotransmission?

The Proteoform Puzzle: Unlocking the Next Frontier

Newsletters you may be interested in