Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

UK's first TEDMEDLive Bristol event to be held at MShed

Could the quantum computing revolution transform drug development, are there new approaches for improving sleep and do people benefit from being diagnosed with early-stage dementia? These are some of the questions that will be discussed at the UK's first TEDMEDLive Bristol event at the MShed on Thursday [18 April].

16 Apr 2013

Junk DNA plays important role in brain development

Specific DNA once dismissed as junk plays an important role in brain development and might be involved in several devastating neurological diseases, UC San Francisco scientists have found.

16 Apr 2013

NeuroDerm enrolls patients for Phase IIa clinical trial of ND0612

NeuroDerm, Ltd. announced today that enrollment of patients is ongoing in its Phase IIa clinical trial of ND0612, a novel drug formulation for the treatment of Parkinson's disease.

16 Apr 2013

Study: p38α MAPK protein functions as important switch to drive inflammatory responses in brain

Even a mild injury to the brain can have long lasting consequences, including increased risk of cognitive impairment later in life. While it is not yet known how brain injury increases risk for dementia, there are indications that chronic, long-lasting, inflammation in the brain may be important.

16 Apr 2013

Mental exercise may help prevent cognitive decline in healthy older adults

Cognitive training exercises - or mental exercise - may help prevent cognitive decline in healthy older adults, while evidence for the benefits of pharmacologic substances and exercise is weak, outlines a review published in CMAJ.

16 Apr 2013

Nutrition Science Initiative to study link between diet, obesity and obesity-related diseases

Just six months after its official launch, the Nutrition Science Initiative has received a $40 million commitment from the Laura and John Arnold Foundation to fund three experiments investigating the link between diet, obesity, and obesity-related diseases, including diabetes, heart disease, stroke, Alzheimer's disease, and cancer.

15 Apr 2013

Researchers study gene that contributes to late-onset Alzheimer's disease in African-Americans

Researchers at Mayo Clinic in Florida participated in a nationwide study that found minor differences between genes that contribute to late-onset Alzheimer's disease in African-Americans and in Caucasians.

15 Apr 2013

RUB researchers develop new hypothesis on occurrence of Alzheimer's disease

A new hypothesis has been developed by researchers in Bochum on how Alzheimer's disease could occur. They analysed the interaction of the proteins FE65 and BLM that regulate cell division.

15 Apr 2013

Study sheds light on role of microglia during progression of Alzheimer's disease

The plaque deposits in the brain of Alzheimer's patients are surrounded by the brain's own immune cells, the microglia. This was already recognized by Alois Alzheimer more than one hundred years ago. But until today it still remains unclear what role microglia play in Alzheimer's disease.

12 Apr 2013

Alzheimer's Association lauds Obama Administration for dedicating additional $100M to fight Alzheimer's

The Alzheimer's Association commends the Obama Administration for dedicating an additional $100 million within the President's FY 2014 budget toward the fight against Alzheimer's and the implementation of the National Plan to Address Alzheimer's Disease.

12 Apr 2013

Omeros' GPCR platform unlocks new drug targets against multiple sclerosis

Omeros Corporation today announced positive data in the most commonly used model for studying the clinical and pathological features of multiple sclerosis (MS), further advancing its development program of GPR17-targeting compounds for the treatment of MS. Compounds previously discovered by Omeros that inhibit GPR17, an orphan G protein-coupled receptor (GPCR) unlocked by Omeros, significantly improved function from experimental autoimmune encephalomyelitis (EAE) in mice.

11 Apr 2013

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Scientists at The Scripps Research Institute have shed light on one of the major toxic mechanisms of Alzheimer's disease. The discoveries could lead to a much better understanding of the Alzheimer's process and how to prevent it.

11 Apr 2013

Many HDLS patients still incorrectly diagnosed

The very serious hereditary disease HDLS was discovered in 1984 in Sweden. Many HDLS patients are still incorrectly diagnosed with Alzheimer's disease, MS or Parkinson's disease, but researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, have now developed a more certain diagnosis method - and are seeking to find a treatment for the "unknown" neurological disorder.

11 Apr 2013

Incidence of late-onset Alzheimer disease higher among African Americans

In a meta-analysis of data from nearly 6,000 African Americans, Alzheimer disease was significantly associated with a gene that have been weakly associated with Alzheimer disease in individuals of European ancestry, although additional studies are needed to determine risk estimates specific for African Americans, according to a study in the April 10 issue of JAMA, a Genomics theme issue.

11 Apr 2013

Research: African-Americans with ABCA7 gene variant have double risk of developing AD

African-Americans with a variant of the ABCA7 gene have almost double the risk of developing late-onset Alzheimer's disease compared with African-Americans who lack the variant.

10 Apr 2013

Researchers develop new imaging system for mouse brain studies

Setting a mouse free to roam might alarm most people, but not so for nuclear imaging researchers from the U.S. Department of Energy's Thomas Jefferson National Accelerator Facility, Oak Ridge National Laboratory, Johns Hopkins Medical School and the University of Maryland who have developed a new imaging system for mouse brain studies.

10 Apr 2013

Cognoptix provides update on multi-site clinical trial of SAPPHIRE II eye test

Cognoptix announced today that it has reached the halfway point in a multi-site clinical trial of its SAPPHIRE II eye test designed to identify Alzheimer's disease patients via a beta amyloid ("Ab") signature in their eyes.

10 Apr 2013

Research sheds light on malaria-related parasite's transition from acute to chronic stage

A new discovery about the malaria-related parasite Toxoplasma gondii -- which can threaten babies, AIDS patients, the elderly and others with weakened immune function -- may help solve the mystery of how this single-celled parasite establishes life-long infections in people.

10 Apr 2013

Weill Cornell Medical College sets up new Feil Family Brain and Mind Research Institute

Weill Cornell Medical College has established the new Feil Family Brain and Mind Research Institute, a unique, multidisciplinary translational neuroscience research hub. Named in honor of long-time benefactors Gertrude and Louis Feil, the institute was created with a generous $28 million gift from the Feil Family.

9 Apr 2013

Roche, Isis Pharmaceuticals to develop neurodegenerative therapeutics for Huntington's disease

Roche and Isis Pharmaceuticals, Inc today announced that they have formed an alliance to develop treatments for Huntington's disease based on Isis' antisense oligonucleotide technology.

9 Apr 2013

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

UK's first TEDMEDLive Bristol event to be held at MShed

Junk DNA plays important role in brain development

NeuroDerm enrolls patients for Phase IIa clinical trial of ND0612

Study: p38α MAPK protein functions as important switch to drive inflammatory responses in brain

Mental exercise may help prevent cognitive decline in healthy older adults

Nutrition Science Initiative to study link between diet, obesity and obesity-related diseases

Researchers study gene that contributes to late-onset Alzheimer's disease in African-Americans

RUB researchers develop new hypothesis on occurrence of Alzheimer's disease

Study sheds light on role of microglia during progression of Alzheimer's disease

Alzheimer's Association lauds Obama Administration for dedicating additional $100M to fight Alzheimer's

Omeros' GPCR platform unlocks new drug targets against multiple sclerosis

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Many HDLS patients still incorrectly diagnosed

Incidence of late-onset Alzheimer disease higher among African Americans

Research: African-Americans with ABCA7 gene variant have double risk of developing AD

Researchers develop new imaging system for mouse brain studies

Cognoptix provides update on multi-site clinical trial of SAPPHIRE II eye test

Research sheds light on malaria-related parasite's transition from acute to chronic stage

Weill Cornell Medical College sets up new Feil Family Brain and Mind Research Institute

Roche, Isis Pharmaceuticals to develop neurodegenerative therapeutics for Huntington's disease

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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