Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

First Edition: April 3, 2013

Today's headlines include reports about how the latest round of payment rates for private Medicare plans led to stock market gains for insurers.

3 Apr 2013

Research facilitates development of treatments, cures to Alzheimer's disease

A team of researchers at The New York Stem Cell Foundation Research Institute led by Scott Noggle, PhD, Director of the NYSCF Laboratory and the NYSCF - Charles Evans Senior Research Fellow for Alzheimer's Disease, and Michael W. Nestor, PhD, a NYSCF Postdoctoral Research Fellow, has developed a technique to produce three-dimensional cultures of induced pluripotent stem cells called embryoid bodies, amenable to live cell imaging and to electrical activity measurement.

3 Apr 2013

Risk prediction tools that estimate future risk of stroke and heart disease may also predict memory loss

Risk prediction tools that estimate future risk of heart disease and stroke may be more useful predictors of future decline in cognitive abilities, or memory and thinking, than a dementia risk score, according to a new study published in the April 2, 2013, print issue of Neurology®, the medical journal of the American Academy of Neurology.

2 Apr 2013

MIT scientists model structure of alpha synuclein protein associated with Parkinson's

Clumps of proteins that accumulate in brain cells are a hallmark of neurological diseases such as dementia, Parkinson's disease and Alzheimer's disease. Over the past several years, there has been much controversy over the structure of one of those proteins, known as alpha synuclein.

2 Apr 2013

Physical, mental activities improve cognitive function in older adults, study finds

A randomized controlled trial finds that 12 weeks of physical plus mental activity in inactive older adults with cognitive complaints was associated with significant improvement in cognitive function but there was no difference between intervention and control groups, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.

2 Apr 2013

Johns Hopkins scientists identify role of central nervous system cell in development of ALS

Johns Hopkins scientists say they have evidence from animal studies that a type of central nervous system cell other than motor neurons plays a fundamental role in the development of amyotrophic lateral sclerosis, a fatal degenerative disease.

1 Apr 2013

New research shows surgical menopause increases cognitive decline and dementia

Women who abruptly and prematurely lose estrogen from surgical menopause have a two-fold increase in cognitive decline and dementia.

30 Mar 2013

Studies examine existing opportunity to improve interventions, outcomes of TBI in older adults

Considerable opportunity exists to improve interventions and outcomes of traumatic brain injury in older adults, according to three studies published in the recent online issue of NeuroRehabilitation by researchers from the Icahn School of Medicine at Mount Sinai.

30 Mar 2013

New evidence shows older adults with dementia can be taken off antipsychotic medications

Most older adults with dementia can successfully be taken off antipsychotic medications, which have negative side effects and increase the risk of death, finds a new evidence review from The Cochrane Library.

29 Mar 2013

Study: Protein clumps in nerve cells are pathologies of Parkinson's disease

Clumps of α-synuclein protein in nerve cells are hallmarks of many degenerative brain diseases, most notably Parkinson's disease.

29 Mar 2013

New way to predict woman’s final menstrual period

A new UCLA-led study suggests a way to predict when a woman will have her final menstrual period. The findings, published in the April issue of the peer-reviewed Journal of Clinical Endocrinology and Metabolism, could help women and physicians gauge the onset of menopause-related bone loss, which generally begins a year prior to the last period.

28 Mar 2013

Data shows efficacy of MANF in neuroprotection 6-hydroxydopamine rat models of Parkinson's disease

Amarantus BioScience, Inc., a biotechnology company discovering and developing treatments and diagnostics for diseases associated with neurodegeneration and apoptosis, today reported positive preclinical data for its lead therapeutic MANF in neuroprotection 6-hydroxydopamine (6-OHDA) rat models of Parkinson's disease.

28 Mar 2013

Navidea commences enrollment in NAV4694 Phase 2b study to detect erebral β-amyloid plaque

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, today announced that enrollment has commenced in its Phase 2b, open-label, safety and efficacy positron emission tomography imaging study of [18F]NAV4694 for detection of cerebral β-amyloid plaque in subjects diagnosed with Mild Cognitive Impairment.

28 Mar 2013

Researchers reprogramming skin cells into brain cells to understand Alzheimer's disease

Sam Gandy, MD, PhD, of the Icahn School of Medicine at Mount Sinai is leading an international team of researchers working to reprogram skin cells into brain cells to gain a better understanding of Alzheimer's disease.

28 Mar 2013

Fruit flies raised on organic diets record better health outcomes

A new study looking at the potential health benefits of organic versus non-organic food found that fruit flies fed an organic diet recorded better health outcomes than flies fed a nonorganic diet.

27 Mar 2013

Molecular biologist hopes to learn why degenerative disorder affects specific brain cells

Dr. Santosh D'Mello, professor of molecular and cell biology at the University of Texas at Dallas, has received a federal grant for research that may shed light on why and how specific brain cells are affected by Huntington's disease, a devastating, degenerative brain disorder.

27 Mar 2013

Lundbeck, Otsuka reach agreement to develop and commercialize Lu AE58054

H. Lundbeck A/S and Otsuka Pharmaceutical Co., Ltd. today announced a license and development agreement for Lu AE58054, a selective 5HT6 receptor antagonist currently in development for the treatment of Alzheimer's disease.

26 Mar 2013

Two researchers awarded grants to develop indicators, biomarkers for dementia with Lewy bodies

The Lewy Body Dementia Association and the Alzheimer's Drug Discovery Foundation have awarded $100,000 each to Omar El-Agnaf, PhD, of United Arab Amirates University and Michelle Mielke, PhD, of Mayo Clinic Rochester to provide one year of support for their research projects focused on developing indicators, or biomarkers, for dementia with Lewy bodies.

26 Mar 2013

Norwegian study shows patients with Parkinson disease have increased risk for dementia

Mild cognitive impairment at the time of Parkinson disease diagnosis appears to be associated with an increased risk for early dementia in a Norwegian study, according to a report published Online First by JAMA Neurology, a JAMA Network publication.

26 Mar 2013

Study: Virus that causes cold sores may be associated with cognitive problems

The virus that causes cold sores, along with other viral or bacterial infections, may be associated with cognitive problems, according to a new study published in the March 26, 2013, print issue of Neurology, the medical journal of the American Academy of Neurology.

26 Mar 2013

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

First Edition: April 3, 2013

Research facilitates development of treatments, cures to Alzheimer's disease

Risk prediction tools that estimate future risk of stroke and heart disease may also predict memory loss

MIT scientists model structure of alpha synuclein protein associated with Parkinson's

Physical, mental activities improve cognitive function in older adults, study finds

Johns Hopkins scientists identify role of central nervous system cell in development of ALS

New research shows surgical menopause increases cognitive decline and dementia

Studies examine existing opportunity to improve interventions, outcomes of TBI in older adults

New evidence shows older adults with dementia can be taken off antipsychotic medications

Study: Protein clumps in nerve cells are pathologies of Parkinson's disease

New way to predict woman’s final menstrual period

Data shows efficacy of MANF in neuroprotection 6-hydroxydopamine rat models of Parkinson's disease

Navidea commences enrollment in NAV4694 Phase 2b study to detect erebral β-amyloid plaque

Researchers reprogramming skin cells into brain cells to understand Alzheimer's disease

Fruit flies raised on organic diets record better health outcomes

Molecular biologist hopes to learn why degenerative disorder affects specific brain cells

Lundbeck, Otsuka reach agreement to develop and commercialize Lu AE58054

Two researchers awarded grants to develop indicators, biomarkers for dementia with Lewy bodies

Norwegian study shows patients with Parkinson disease have increased risk for dementia

Study: Virus that causes cold sores may be associated with cognitive problems

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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