Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

FOXO1 gene may play an important role in pathological mechanisms of Parkinson's

A recent study led by researchers at Boston University School of Medicine (BUSM) revealed that the FOXO1 gene may play an important role in the pathological mechanisms of Parkinson's disease.

29 Jun 2012

Researchers identify genes that influence degeneration of the hippocampus

In a genome-wide association (GWA) study, researchers from Boston University Schools of Medicine (BUSM) and Public Health (BUSPH) have identified several genes which influence degeneration of the hippocampus, the part of the brain most associated with Alzheimer disease (AD).

29 Jun 2012

New laboratory model for Huntington's disease

Cedars-Sinai scientists have joined with expert colleagues around the globe in using stem cells to develop a laboratory model for Huntington's disease, allowing researchers for the first time to test directly on human cells potential treatments for this fatal, inherited disorder.

29 Jun 2012

Researchers create 'Huntington's disease in a dish' to enable search for treatment

Johns Hopkins researchers, working with an international consortium, say they have generated stem cells from skin cells from a person with a severe, early-onset form of Huntington's disease (HD), and turned them into neurons that degenerate just like those affected by the fatal inherited disorder.

29 Jun 2012

Potential risk factors for disorder that causes people to kick or punch during sleep

Smoking, head injury, pesticide exposure, farming and less education may be risk factors for a rare sleep disorder that causes people to kick or punch during sleep, according to a study published in the June 27, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Jun 2012

HHS honors UNTHSC, Brookdale Senior Living with $7.3M Health Care Innovation award

The UNT Health Science Center and Brookdale Senior Living, the largest senior living community operator in the country, recently were awarded a $7.3 million Health Care Innovation award from the U.S. Department of Health and Human Services for a program designed to reduce hospital re-admissions of residents in assisted-living situations.

28 Jun 2012

New compound could treat certain types of genetic disorders in muscles

Scientists at UCLA have identified a new compound that could treat certain types of genetic disorders in muscles. It is a big first step in what they hope will lead to human clinical trials for Duchenne muscular dystrophy.

28 Jun 2012

Humanetics receives U.S. patent for NIC5-15 to treat Alzheimer's

The US Patent and Trademark Office has issued a patent supporting a long-term, multi-year research and development collaboration between Mount Sinai School of Medicine (MSSM) and Humanetics Corporation to develop and commercialize a safe and effective means to prevent or slow the progression of Alzheimer's disease. Humanetics is the exclusive licensee for this patent.

28 Jun 2012

Scientists discover serum biochemical signature that predicts Alzheimer's

Scientists from VTT Technical Research Centre of Finland in collaboration with the University of Eastern Finland have recently discovered a serum biochemical signature which predicts progression to Alzheimer's disease months or even years before the first symptoms of the disease occur. The goal of the new collaboration between VTT and GE Healthcare is to validate this biomarker in a large patient cohort as well as to discover novel biomarker candidates.

27 Jun 2012

Researchers identify latest gene associated with typical late-onset Lewy body Parkinson's

An international team led by human genetic researchers at the University of British Columbia and Vancouver Coastal Health has identified the latest gene associated with typical late-onset Lewy body Parkinson's disease (PD), with the help of a Canadian Mennonite family of Dutch-German-Russian ancestry.

27 Jun 2012

Study shows how brain insulin resistance contributes to neurodegeneration in AD

Rhode Island Hospital researcher Suzanne de la Monte, M.D., has found a link between brain insulin resistance (diabetes) and two other key mediators of neuronal injury that help Alzheimer's disease (AD) to propagate.

27 Jun 2012

Research reveals benefits of exercise in combating Alzheimer's disease

In a recent Journal of Biological Chemistry "Paper of the Week," research led by Ayae Kinoshita at the Kyoto University Graduate School of Medicine in Japan reveals the benefits of exercise in combating Alzheimer's disease.

27 Jun 2012

Care home residents denied right to consensual sex due to fears over safety and ageism

Concerns about safety, and ageism, are needlessly denying elderly care home residents what is often one of their few remaining pleasures - the right to consensual sex - say specialists in the Journal of Medical Ethics.

26 Jun 2012

p53 protein may show a typical prion-like behavior when mutated

Prions, the causal agents of Mad Cow and other diseases, are very unique infectious particles. They are proteins in which the complex molecular three-dimensional folding process just went astray. For reasons not yet understood, the misfolding nature of prions is associated to their ability to sequester their normal counterparts and induce them to also adopt a misfolding conformation.

26 Jun 2012

Feinstein Institute to train clinicians on how to better care for patients with schizophrenia

The Zucker Hillside Hospital campus of the Feinstein Institute for Medical Research has been approved for a $9.3+ million federal grant to train clinicians on how to better care for patients with schizophrenia.

26 Jun 2012

New Alzheimer's Society funded project to investigate role of chronic stress in dementia

Chronic stress is being investigated in a new Alzheimer's Society funded research project as a risk factor for developing dementia.

26 Jun 2012

Hospitalization, delirium worsen AD patients’ outcomes

Individuals with Alzheimer’s disease who are hospitalized are at risk for adverse outcomes including institutionalization, cognitive decline, and death, show study results.

25 Jun 2012

Neuralstem commences dosing in NSI-189 Phase Ib trial for major depressive disorder

Neuralstem, Inc. announced that the first patients were dosed in Phase Ib of its ongoing trial to test the safety of NSI-189 in the treatment of major depressive disorder (MDD).

25 Jun 2012

Research roundup: Helping the homeless transition out of the hospital

Transitioning from a hospital visit can be challenge for many patients, but the homeless face particular difficulties as they move to a shelter, or even back to the streets. Researchers in this study surveyed 98 homeless individuals in New Haven, Conn., as well as interviewed them about their experiences leaving the hospital. More than half said that their providers did not address housing or transportation, and 11 percent reported living on the streets on the night of their discharge. The authors recommend "improved assessment of housing status, communication between hospital and shelter providers, and arrangement of safe transportation" for homeless individuals.

23 Jun 2012

GMCSF linked with rapid cognitive recovery in patients with cancer

Growth factors shown to cure Alzheimer's disease in a mouse model and administered to cancer patients as part of their treatment regimen were linked to significant improvements in the patients' cognitive function following stem cell transplantation, a preliminary clinical study reports.

23 Jun 2012

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

FOXO1 gene may play an important role in pathological mechanisms of Parkinson's

Researchers identify genes that influence degeneration of the hippocampus

New laboratory model for Huntington's disease

Researchers create 'Huntington's disease in a dish' to enable search for treatment

Potential risk factors for disorder that causes people to kick or punch during sleep

HHS honors UNTHSC, Brookdale Senior Living with $7.3M Health Care Innovation award

New compound could treat certain types of genetic disorders in muscles

Humanetics receives U.S. patent for NIC5-15 to treat Alzheimer's

Scientists discover serum biochemical signature that predicts Alzheimer's

Researchers identify latest gene associated with typical late-onset Lewy body Parkinson's

Study shows how brain insulin resistance contributes to neurodegeneration in AD

Research reveals benefits of exercise in combating Alzheimer's disease

Care home residents denied right to consensual sex due to fears over safety and ageism

p53 protein may show a typical prion-like behavior when mutated

Feinstein Institute to train clinicians on how to better care for patients with schizophrenia

New Alzheimer's Society funded project to investigate role of chronic stress in dementia

Hospitalization, delirium worsen AD patients’ outcomes

Neuralstem commences dosing in NSI-189 Phase Ib trial for major depressive disorder

Research roundup: Helping the homeless transition out of the hospital

GMCSF linked with rapid cognitive recovery in patients with cancer

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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