Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Immune checkpoint inhibitors induce rheumatic and musculoskeletal diseases

Checkpoint inhibitor therapy is a form of cancer treatment immunotherapy currently under research. The therapy targets immune checkpoints, key regulators of the immune system that stimulate or inhibit its actions, which tumors can use to protect themselves from attacks by the immune system.

18 Jan 2019

New immune response regulators discovered

The discovery was published in the new iScience journal for interdisciplinary research by Cell Press. The newly discovered regulatory proteins differ significantly from the regulators in mouse immune cells which have been reported earlier. Some of the proteins, such as SATB1 regulating the transcription of several genes, function in the opposite way in human compared to mouse.

16 Jan 2019

Nerve transfer surgery restores arm movement in children with acute flaccid myelitis

An innovative and complex surgery involving nerve transfers is restoring hope and transforming lives torn apart by a mysterious and devastating illness. Acute flaccid myelitis, also known as AFM, strikes without warning, shows no mercy and frequently results in paralysis.

15 Jan 2019

Vitamin D supplements are of no gain to those over 70, study shows

There is little benefit for those over 70 taking higher dose vitamin D supplements to improve their bone strength and reduce the risk of falls, new research has revealed.

14 Jan 2019

Excess belly fat may lead to a reduction in gray matter

A new study has found that excess abdominal fat is associated with a lower volume of gray matter in the brain, resulting in a smaller brain size.

11 Jan 2019

Unconventional T cells may account for failure of IL-17 inhibition in rheumatoid arthritis

Spondyloarthritis is one of the most common types of chronic joint inflammation affecting nearly 1-2% of the Western population.

10 Jan 2019

Research examines patterns in back pain over time

Back pain is among the most frequently reported health problems in the world. New research published in Arthritis Care & Research, an official journal of the American College of Rheumatology and the Association of Rheumatology Health Professionals, examines patterns in back pain over time and identifies the patient characteristics and the extent of healthcare and medication use (including opioids) associated with different patterns.

10 Jan 2019

Researchers identify promising therapeutic option to treat multiple sclerosis

Researchers at the Medical Center of Johannes Gutenberg University Mainz (JGU) identified an innovative and promising therapeutic option to treat multiple sclerosis.

10 Jan 2019

Mechanism underlying impaired allergic inflammation in children may explain hygiene hypothesis

The hygiene hypothesis may explain why asthma and other allergic airway diseases have dramatically increased over the past decades in industrialized countries.

9 Jan 2019

Heberden's nodes may be associated with knee osteoarthritis

Heberden's nodes are bony enlargements of the finger joints that are readily detectable in a routine physical exam and are considered hallmarks of osteoarthritis. A new Arthritis & Rheumatology study found that the presence of HNs may also indicate structural damage associated with knee osteoarthritis.

9 Jan 2019

Health care industry spends $30b a year pushing its wares, from drugs to stem cell treatment

Hoping to earn its share of the $3.5 trillion health care market, the medical industry is pouring more money than ever into advertising its products — from high-priced prescriptions to do-it-yourself genetic tests and unapproved stem cell treatments.

8 Jan 2019

Exercise hormone can prevent Alzheimer's finds study

According to a large worldwide study, the hormone that is produced in the body during exercise called irisin, can prevent and delay the onset of mental faculty decline and Alzheimer’s disease. The results of the study were published in the latest issue of the journal Nature Medicine.

8 Jan 2019

Cellular protein signal can be manipulated to favor bone building

In experiments in rats and human cells, Johns Hopkins Medicine researchers say they have added to evidence that a cellular protein signal that drives both bone and fat formation in selected stem cells can be manipulated to favor bone building.

7 Jan 2019

Researchers develop mouse model to study consequences of fungal infection in the brain

Fungal infections are emerging as a major medical challenge, and a team led by researchers at Baylor College of Medicine has developed a mouse model to study the short-term consequences of fungal infection in the brain.

4 Jan 2019

Researchers review applications, properties, and pharmacological potentials of rose hip

The genus Rosa from family Rosaceae is one of the most widespread species from the family. One species, rose hip, is known as a good source of different types of micronutrients and phytochemicals such as phenolic acids, tannins, and flavonoids. It is known as a traditional treatment in folk medicine.

28 Dec 2018

MUSC researchers link higher levels of AGEs to ER-positive breast cancer risk

Poor diet and lack of exercise are associated with cancer development, but the underlying biology is not well understood. Advanced glycation end products could offer a biological link to help us understand how certain lifestyle behaviors increase cancer risk or lessen the likelihood that an anti-cancer therapy will be effective.

28 Dec 2018

How physical activity decreases belly fat in humans

Some of you may have made a New Year's resolution to hit the gym to tackle that annoying belly fat. But have you ever wondered how physical activity produces this desired effect? A signaling molecule called interleukin-6 plays a critical role in this process, researchers report December 27 in the journal Cell Metabolism.

28 Dec 2018

Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Immune checkpoint inhibitors induce rheumatic and musculoskeletal diseases

New immune response regulators discovered

Nerve transfer surgery restores arm movement in children with acute flaccid myelitis

Vitamin D supplements are of no gain to those over 70, study shows

Excess belly fat may lead to a reduction in gray matter

Unconventional T cells may account for failure of IL-17 inhibition in rheumatoid arthritis

Research examines patterns in back pain over time

Researchers identify promising therapeutic option to treat multiple sclerosis

Mechanism underlying impaired allergic inflammation in children may explain hygiene hypothesis

Heberden's nodes may be associated with knee osteoarthritis

Health care industry spends $30b a year pushing its wares, from drugs to stem cell treatment

Exercise hormone can prevent Alzheimer's finds study

Cellular protein signal can be manipulated to favor bone building

Researchers develop mouse model to study consequences of fungal infection in the brain

Researchers review applications, properties, and pharmacological potentials of rose hip

MUSC researchers link higher levels of AGEs to ER-positive breast cancer risk

How physical activity decreases belly fat in humans

Yale researchers use arthritis medication to treat patient with disfiguring sarcoidosis

Researchers reveal how dietary intervention can help prevent autoimmune disease in mice

Scripps Research finds molecular cause of a group of rare autoimmune disorders

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Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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