Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

PROLOR commences hGH-CTP Phase II trial in children with GHD

PROLOR Biotech, Inc., a company developing next generation biobetter therapeutic proteins, today announced initiation of a Phase II clinical trial of its long-acting CTP-modified version of human growth hormone (hGH-CTP) in children with growth hormone deficiency.

20 Mar 2012

Researchers identify Wnt pathway as new target for scleroderma therapy

A genetic pathway previously known for its role in embryonic development and cancer has been identified as a target for systemic sclerosis, or scleroderma, therapy.

20 Mar 2012

Researchers show how errant form of LYP can disrupt the immune system

Autoimmune diseases, such as Type I diabetes and rheumatoid arthritis, are caused by an immune system gone haywire, where the body's defense system assaults and destroys healthy tissues. A mutant form of a protein called LYP has been implicated in multiple autoimmune diseases, but the precise molecular pathway involved has been unknown.

19 Mar 2012

Scientist generates mutant version of IL-2 protein to treat advanced cancers

The utility of a naturally occurring protein given, sometimes to great effect, as a drug to treat advanced cancers is limited by the severe side effects it sometimes causes. But a Stanford University School of Medicine scientist has generated a mutant version of the protein whose modified shape renders it substantially more potent than the natural protein while reducing its toxicity.

19 Mar 2012

Positive data from VBL Therapeutics' VB-201 Phase 2 study on psoriasis, atherosclerosis

VBL Therapeutics, a clinical stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, today announced that a Phase 2 sub-study of VB-201 in moderate to severe psoriasis patients with cardiovascular risk has successfully achieved its primary endpoint demonstrating a statistically significant reduction in vascular inflammation associated with atherosclerotic lesions as measured by PET-CT imaging.

17 Mar 2012

Abbott initiates enrollment in two HUMIRA Phase 3 trials for moderate to severe HS

Abbott today announced the initiation of two Phase 3 clinical trials designed to evaluate the safety and efficacy of an investigational use of HUMIRA (adalimumab) in adult patients with moderate to severe hidradenitis suppurativa.

16 Mar 2012

NYC Bangladeshi community experiences numerous barriers to diabetes care

A new research survey conducted by the Center for the Study of Asian American Health at NYU Langone Medical Center shows the Bangladeshi community in New York City experiences numerous barriers to diabetes care because of limited English proficiency and lack of diabetes awareness.

15 Mar 2012

H. pylori bacteria associated with elevated levels of HbA1c

A new study by researchers at NYU Langone Medical Center reveals that the presence of Helicobacter pylori (H. pylori) bacteria is associated with elevated levels of glycosylated hemoglobin (HbA1c), an important biomarker for blood glucose levels and diabetes.

15 Mar 2012

Anti-inflammatory drugs may offer novel treatment for CHD

A large international study indicates that anti-inflammatory drugs may become a new tool for preventing and treating coronary heart disease (CHD), the leading global cause of death.

15 Mar 2012

MAPKAP kinase 2 plays an important role in progression of GIST

Gastrointestinal stroma tumours (GIST) are a very particular challenge for cancer research. For once the tumours, which are mostly located in the stomach, are relatively rare (approx. 100 new cases/year in Austria) and hence are difficult to research. On the other side its behaviour varies quite a lot. While some GIST tumours are relatively harmless, others may become metastatic.

15 Mar 2012

Vejthani Hospital offers Unicompartmental Knee Arthroplasty in Thailand

Vejthani Hospital Bangkok offers Unicompartmental Knee Arthroplasty to get better range of motion at Vejthani TJR center, the top international hospital in Thailand.

15 Mar 2012

New UCLA Alzheimer's and Dementia Care program for patients, caregivers

Alzheimer's disease affects an estimated 5.4 million people in the U.S., some 480,000 of them in California. Nearly half of all people 85 and older will be stricken with the disease. The overall burden of dementia is still higher, with Alzheimer's accounting for only 60 to 80 percent of dementia cases.

15 Mar 2012

Researchers double time to store donated cartilage

For years, doctors have been able to treat defects in joint cartilage by grafting cartilage donated from cadavers into patients' bad joints. Using current methods, donated cartilage can be stored for 28 days for a transplant before the tissue becomes too degraded to transplant into a patient. Now, researchers from the University of Missouri have found a way to store donated cartilage more than twice as long.

14 Mar 2012

FDA panel favors continued research on novel pain medicine

A panel of experts for the U.S. Food and Drugs Administration (FDA) this Monday recommended that the federal government should allow continued testing of an experimental class of pain drugs for arthritis, despite links to bone decay and joint failure.

13 Mar 2012

Over 125,000 NYU Langone patients now use new biometric identification system

Launched just nine months ago, more than 125,000 patients at NYU Langone Medical Center are now using PatientSecure, a cutting-edge biometric identification system.

13 Mar 2012

JAK-STAT inhibitors reverse MS-like disease in mice

A new class of drugs completing clinical trials soon for rheumatoid arthritis should be examined as a treatment for multiple sclerosis, according to the authors of a University of Alabama at Birmingham study published today in the Proceedings of the National Academy of Sciences.

13 Mar 2012

Officials examine Medicaid coverage, quality in context of burgeoning costs

Growing demand for Medicaid services puts a burden on states as they wrestle with tight budgets and patient quality issues.

12 Mar 2012

Researchers unlock mystery of how an inflammatory molecule is produced in the body

Cedars-Sinai researchers have unlocked the mystery of how an inflammatory molecule is produced in the body, a discovery they say could lead to advances in the treatment of rheumatoid arthritis, Type 2 diabetes and numerous other chronic diseases that affect tens of millions of people.

12 Mar 2012

Antares Pharma fourth quarter revenues increase 65% to $5.4 million

Antares Pharma, Inc. today reported financial and operating results for the fourth quarter and full year ended December 31, 2011 and outlined key objectives and milestones for 2012.

12 Mar 2012

First Edition: March 12, 2012

Today's health policy headlines focus significant attention on key issues, dynamics and even personalities that will be in play when the Supreme Court takes up the health law later this month.

12 Mar 2012