Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

MRI shows elevated BMI linked to greater extent and severity of degenerative disc disease

One of the largest studies to investigate lumbar spine disc degeneration found that adults who are overweight or obese were significantly more likely to have disc degeneration than those with a normal body mass index (BMI).

30 Jan 2012

Leprosy pathogen exploits micro-RNAs to weaken immune response

A team of UCLA scientists has found that the pathogen that causes leprosy has a remarkable ability to avoid the human immune system by inhibiting the antimicrobial responses important to our defenses.

30 Jan 2012

Pleasurability of scratching for itch relief is related to body location

New research from Gil Yosipovitch, M.D., Ph.D., professor of dermatology at Wake Forest Baptist Medical Center and a world-renowned itch expert, shows that how good scratching an itch feels is related to the itch's location.

30 Jan 2012

Researchers develop new physical form of proteins to improve treatments for cancer

A new physical form of proteins developed by researchers at The University of Texas at Austin could drastically improve treatments for cancer and other diseases, as well as overcome some of the largest challenges in therapeutics: delivering drugs to patients safely, easily and more effectively.

30 Jan 2012

New discovery paves way for genetic screening test

Researchers at the Columbia University College of Dental Medicine have identified a genetic variation that raises the risk of developing serious necrotic jaw bone lesions in patients who take bisphosphonates, a common class of osteoclastic inhibitors.

27 Jan 2012

Study finds clear association between obesity and pain in 1M Americans

A clear association between obesity and pain - with higher rates of pain identified in the heaviest individuals - was found in a study of more than one million Americans published January 19 in the online edition of Obesity.

27 Jan 2012

Study shows lack of physical activity in 42% of adults with RA

A new study, funded by a grant from the National Institute for Arthritis and Musculoskeletal and Skin Diseases (NIAMS), found that two in five adults (42%) with rheumatoid arthritis (RA) were inactive.

27 Jan 2012

New system safe, effective in delivering CsA to organ transplant patients

A new system for delivering a drug to organ transplant patients, which could avoid the risk of harmful side effects, is being developed by scientists at the University of Strathclyde in Glasgow.

27 Jan 2012

Amgen enters definitive merger agreement to acquire Micromet

Amgen and Micromet, Inc. today announced that the companies have entered into a definitive merger agreement under which Amgen will acquire Micromet, a biotechnology company founded in Germany with its research and development (R&D) center in Munich and headquarters in Rockville, Md., for $11 per share in cash.

27 Jan 2012

Celgene signs definitive merger agreement to acquire Avila

Celgene Corporation and Avila Therapeutics, Inc., a privately held biotechnology company developing targeted covalent drugs that treat diseases through protein silencing, today announced a definitive merger agreement under which Celgene Corporation will acquire Avila Therapeutics, Inc.

26 Jan 2012

Aphios receives NIH's Phase II SBIR grant to develop APH-0703 for AD

Aphios Corporation has received a Phase II SBIR grant from the National Institutes of Health (NIH) amounting to $2.4 million over two years. The National Institute on Aging (NIA), part of the NIH, awarded the grant to the Aphios Corporation to develop an "Alzheimer's Disease Therapeutic."

24 Jan 2012

Johnson & Johnson fourth quarter sales increase 3.9% to $16.3 billion

Johnson & Johnson today announced sales of $16.3 billion for the fourth quarter of 2011, an increase of 3.9% as compared to the fourth quarter of 2010. Operational sales increased 4.0% and the negative impact of currency was 0.1%.

24 Jan 2012

EMA CHMP issues positive opinion to MSD's REMICADE for treatment of pediatric UC

MSD today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion recommending the use of REMICADE (infliximab) in the treatment of severely active ulcerative colitis (UC) in pediatric patients ages 6 to 17 years, who have had an inadequate response to conventional therapy, including corticosteroids and 6-mercaptopurine or azathioprine, or who are intolerant to or have medical contraindications for such therapies.

21 Jan 2012

Risperdal lawsuit settlement: Largest Medicaid fraud case in Texas

Texas and Janssen Pharmaceuticals reach a $158 million settlement on a suit claiming that the company lied about the efficacy of the anti-psychotic medicine.

21 Jan 2012

TCRH forms new joint venture with Duke LifePoint

Twin County Regional Healthcare (TCRH) has entered into a new agreement that will secure the hospital's position as a trusted provider of quality healthcare services for years to come. The TCRH Board of Directors and Duke LifePoint Healthcare today announced they have signed a definitive agreement to jointly own and operate Twin County Regional Healthcare and its affiliated assets.

20 Jan 2012

New book focuses on improving care for chronic diseases

Why does health care need to be redesigned? First - the current system is broken. It costs too much, and too often yields little value for patients and society. Second - it's fixable. The editors and authors of Great Health Care - Making It Happen are convinced of it.

20 Jan 2012

Testing for osteoporosis – how often?

A new study shows that many women who get screened for osteoporosis may not need it. It suggests that the current guidelines result in too many unnecessary tests, increasing costs and sometimes spurring unnecessary treatment.

19 Jan 2012

The AJMS publishes updates on type 2 diabetes, STIs

Research is leading to new insights on two major public health challenges: preventing the spread of sexually transmitted infections (STIs) and improving disease control for patients with type 2 diabetes. Expert updates on these critical topics appear in a special symposium section of the January issue of The American Journal of the Medical Sciences (The AJMS), official journal of the Southern Society for Clinical Investigation.

19 Jan 2012

Patients with PsA may benefit from new medications and surgeries

Medications or biologic agents that target T-cells, white blood cells involved in the body's immune system, appear to offer significant benefit to patients suffering from psoriatic arthritis (PsA), a type of arthritis that affects up to 48 percent of patients with the skin disease psoriasis, according to a new review article in the Journal of the American Academy of Orthopaedic Surgeons.

19 Jan 2012