Arthritis News and Research

Latest Arthritis News and Research

UCLA stem cell researchers track early development of human articular cartilage

Stem cell researchers from UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have published the first study to identify the origin cells and track the early development of human articular cartilage, providing what could be a new cell source and biological roadmap for therapies to repair cartilage defects and osteoarthritis. These revolutionary therapies could reach clinical trials within three years.

13 Dec 2013

Research paper provides first evidence-based recommendations for using PRP in orthopaedic care

Platelet-rich plasma (PRP) has grabbed headlines in recent years for its role in helping some of sports' biggest stars return to play following injury -including golfer Tiger Woods, Super Bowl winner Hines Ward and NBA legend Kobe Bryant.

12 Dec 2013

MedImmune, Johns Hopkins University enter into $6.5M research collaboration

MedImmune, AstraZeneca’s global biologics research and development arm, and The Johns Hopkins University today announced they have entered into a five-year, $6.5 million research collaboration.

12 Dec 2013

Crealta to acquire all assets of Savient Pharmaceuticals

Savient Pharmaceuticals, Inc. ("Savient") announced that it has reached agreement on the terms of an acquisition agreement with Crealta Pharmaceuticals LLC ("Crealta") through which Crealta would acquire substantially all of the assets of Savient, including all KRYSTEXXA® assets, for gross proceeds of approximately $120.4 million.

11 Dec 2013

Experimental compound reduces joint inflammation in animal models of rheumatoid arthritis

An experimental compound synthesized and developed by scientists from the Florida campus of The Scripps Research Institute has the capacity to significantly reduce joint inflammation in animal models of rheumatoid arthritis, an autoimmune disease that affects more than two million Americans.

11 Dec 2013

Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation

Bone homeostasis requires precise balance between deposition of new bone by osteoblasts and resorption of old bone by osteoclasts. Bone diseases, including osteoporosis and rheumatoid arthritis, are the result of increased osteoclast activity and formation, which allows bone resorption to outpace deposition.

9 Dec 2013

Janssen announces first-of-its-kind pediatric HIV treatment donation program

Janssen, the pharmaceutical companies of Johnson & Johnson, today announced a first-of-its-kind pediatric HIV treatment donation program to improve access to the company's approved HIV medicines for children and adolescents failing HIV treatment in sub-Saharan Africa.

9 Dec 2013

Johns Hopkins researchers discover some cases of scleroderma likely to be initiated by cancer

The Scleroderma Research Foundation today reported that researchers at The Johns Hopkins University have discovered that some cases of scleroderma are likely to have been initiated by cancer.

6 Dec 2013

Scientists identify key factor for limiting inflammatory responses, particularly in skin

Sanford-Burnham scientists have identified the B and T Lymphocyte Attenuator (BTLA) inhibitory receptor as a key factor in limiting inflammatory responses, particularly in the skin. The study, published online today in Immunity, provides clarity on how T cells get fired up to protect against pathogens, and then cool down to restore immune homeostasis.

6 Dec 2013

Manipulation of Wnt/B-catenin pathway provides therapeutic targets for hair loss, skin cancer

A pathway known for its role in regulating adult stem cells has been shown to be important for hair follicle proliferation, but contrary to previous studies, is not required within hair follicle stem cells for their survival, according to researchers with the Perelman School of Medicine at the University of Pennsylvania.

5 Dec 2013

CEL-SCI gets approval to start enrollment for Multikine Phase III study for head and neck cancer

Further advancing one of the largest Phase III trials for head and neck cancer in the world, CEL-SCI Corporation announced today that it has received approval from the Agency for Medicaments and Medical Devices of the government of Bosnia and Herzegovina to begin enrollment of subjects into the Phase III Head and Neck Cancer clinical trial of its investigational cancer immunotherapy treatment Multikine (Leukocyte Interleukin, Injection).

5 Dec 2013

Findings suggest new approach for treating inflammatory bone diseases and skeletal metastases

The skeleton is constantly being remodelled by the breakdown of old bone by cells called osteoclasts and the formation of new bone by cells called osteoblasts. This coordinated activity is essential for maintaining healthy bone. However, excessive osteoclast activity leads to bone destruction in skeletal diseases such as osteoporosis, rheumatoid arthritis and cancer metastases in bone. A family of signaling enzymes known as phosphatidylinositol 3-kinases control diverse cell functions but, up until now, little was known about the function of specific PI3K isoforms in osteoclasts.

5 Dec 2013

IDSA released new guideline for vaccination of immunocompromised hosts

A new guideline released Thursday by the Infectious Diseases Society of America (IDSA) notes that most people with compromised immune systems are especially vulnerable to illness and should receive the flu shot and other vaccinations.

5 Dec 2013

CJR surgeons to perform free joint replacement surgeries on 17 patients

More than 2 million Americans suffer from debilitating hip, knee and joint conditions. Severe joint pain and arthritis can affect almost all aspects of an individual's life, often preventing them from working, enjoying the activities they love and performing simple, everyday tasks.

4 Dec 2013

Young athletes are more prone to hip impingement, say specialists

Hip pain is no longer reserved for older adults. More and more young, active people are developing this problem, which often requires surgery to repair.

4 Dec 2013

Patients with RA today have easier time with daily living than patients diagnosed two decades ago

New research reveals that patients with rheumatoid arthritis today have an easier time with daily living than patients diagnosed two decades ago. According to results of the study published in Arthritis Care & Research, a journal of the American College of Rheumatology, anxiety, depressed mood and physical disability have been cut in half over the last 20 years. Researchers believe a reduction in disease activity is partly responsible for this positive change.

3 Dec 2013

Researchers find evidence that gout clusters in families

It's historically known as 'the king of diseases and the disease of kings' and was long thought to be caused by an overindulgent lifestyle, but now scientists at The University of Nottingham have confirmed that 'gout' strongly runs in families.

3 Dec 2013

Oxygen levels play critical role in determining effectiveness of anti-inflammatory drugs

A new research discovery published in the December 2013 issue of the Journal of Leukocyte Biology yields an important clue toward helping curb runaway inflammation. Oxygen levels play a critical role in determining the severity of the inflammatory response and ultimately the effectiveness of anti-inflammatory drugs.

3 Dec 2013

World-class Krembil Discovery Tower now opens in Canada

The Honourable Dr. K. Kellie Leitch, Minister of Labour and Minister of Status of Women congratulated Toronto Western Hospital today on the opening of the Krembil Discovery Tower, a facility dedicated to research excellence, training the next generation of medical professionals and improving health care for patients across Canada.

2 Dec 2013

Study brings effective hepatitis C cure closer to reality

Scientists at The Scripps Research Institute have determined the most detailed picture yet of a crucial part of the hepatitis C virus, which the virus uses to infect liver cells. The new data reveal unexpected structural features of this protein and should greatly speed efforts to make an effective hepatitis C vaccine.

29 Nov 2013

Arthritis News and Research

Latest Arthritis News and Research

UCLA stem cell researchers track early development of human articular cartilage

Research paper provides first evidence-based recommendations for using PRP in orthopaedic care

MedImmune, Johns Hopkins University enter into $6.5M research collaboration

Crealta to acquire all assets of Savient Pharmaceuticals

Experimental compound reduces joint inflammation in animal models of rheumatoid arthritis

Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation

Janssen announces first-of-its-kind pediatric HIV treatment donation program

Johns Hopkins researchers discover some cases of scleroderma likely to be initiated by cancer

Scientists identify key factor for limiting inflammatory responses, particularly in skin

Manipulation of Wnt/B-catenin pathway provides therapeutic targets for hair loss, skin cancer

CEL-SCI gets approval to start enrollment for Multikine Phase III study for head and neck cancer

Findings suggest new approach for treating inflammatory bone diseases and skeletal metastases

IDSA released new guideline for vaccination of immunocompromised hosts

CJR surgeons to perform free joint replacement surgeries on 17 patients

Young athletes are more prone to hip impingement, say specialists

Patients with RA today have easier time with daily living than patients diagnosed two decades ago

Researchers find evidence that gout clusters in families

Oxygen levels play critical role in determining effectiveness of anti-inflammatory drugs

World-class Krembil Discovery Tower now opens in Canada

Study brings effective hepatitis C cure closer to reality

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

Arthritis News and Research

Latest Arthritis News and Research

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

Newsletters you may be interested in