Arthritis News and Research

Latest Arthritis News and Research

FDA approves OTREXUP injection for adults with RA, children with active pJIA

Antares Pharma, Inc. today announced the approval of OTREXUP (methotrexate) injection by the U.S. Food and Drug Administration. OTREXUP is the first FDA approved subcutaneous methotrexate for once weekly self-administration with an easy-to-use, single dose, disposable auto injector.

14 Oct 2013

Genentech plans to invest over $285M for expansion of biologics manufacturing facilities

Genentech, a member of the Roche Group, today announced plans to invest more than $285 million for the expansion of its biologics manufacturing facilities in Vacaville and Oceanside, California.

14 Oct 2013

Scientists develop new method to regenerate cartilage

Unlike our bones, the cartilage inside our joints is not vascularized (i.e., it has no blood vessels). This is one reason why cartilage does not heal well after an injury. In athletes in particular, joint injuries often result in cartilage degeneration and arthritis. The process is chronic and irreversible, and to this day, no effective treatment exists.

12 Oct 2013

Crucial role of orthopedic surgeons in diagnosing mTBI among trauma care patients

In the United States, approximately 1.4 million people suffer a traumatic brain injury (TBI) each year. Of those injuries, three out of four are minor TBI (mTBI)-a head injury that causes a temporary change in mental status including confusion, an altered level of consciousness, or perceptual or behavioral impairments.

11 Oct 2013

Finding highlights new ways of treating inflammation disorders

A team led by scientists at The Scripps Research Institute (TSRI) has identified key signaling proteins in the inflammation process that contribute to the development of inflammatory diseases such as rheumatoid arthritis, psoriasis, sepsis and inflammatory bowel diseases.

11 Oct 2013

Drugs often fail to bring acromegaly under control in routine clinical practice

Over a quarter of UK patients treated for growth hormone-producing tumours do not achieve 'safe' growth hormone levels, according to a 30 year UK multi-centre study of clinical management of the rare disease acromegaly. The findings by the Society for Endocrinology UK Acromegaly Register, published in the November issue of Clinical Endocrinology, show that drugs to control acromegaly often fail to bring the disease completely under control in routine clinical practice.

10 Oct 2013

Pfizer reports positive results from two tofacitinib Phase 3 trials for chronic plaque psoriasis

Pfizer Inc. announced today top-line results from two Phase 3 clinical trials of tofacitinib, a novel, oral Janus kinase inhibitor that is being investigated for the treatment of adults with moderate-to-severe chronic plaque psoriasis: OPT Compare (A3921080) and OPT Retreatment (A3921111).

10 Oct 2013

TSRI scientists identify set of compounds to treat multiple sclerosis in new way

Scientists at The Scripps Research Institute (TSRI) have identified a set of compounds that may be used to treat multiple sclerosis (MS) in a new way. Unlike existing MS therapies that suppress the immune system, the compounds boost a population of progenitor cells that can in turn repair MS-damaged nerve fibers.

10 Oct 2013

Research points to causes, potential treatment approaches for systemic sclerosis

Using mice, lab-grown cells and clues from a related disorder, Johns Hopkins researchers have greatly increased understanding of the causes of systemic sclerosis, showing that a critical culprit is a defect in the way certain cells communicate with their structural scaffolding

10 Oct 2013

Dry eye disease symptom change independent of tear osmolarity

Tear osmolarity is a poor indicator of treatment response in patients with dry eye disease (DED), suggests research published in the American Journal of Ophthalmology.

9 Oct 2013

Lakewood-Amedex, Wainwright enter into strategic advisory agreement

Lakewood-Amedex Inc., a leading developer of novel anti-infective pharmaceuticals, announced today that it has entered into a strategic advisory agreement with H.C. Wainwright & Co., LLC.

9 Oct 2013

Compugen drug candidate prevents autoimmune type I diabetes in animal model

Compugen Ltd., announced today that CGEN-15001, an Fc fusion protein drug candidate derived from a novel immune checkpoint protein discovered by Compugen, has been shown to be highly efficient in preventing the development of disease in a well-accepted animal model of autoimmune type I diabetes, known also as juvenile diabetes.

9 Oct 2013

Experts offer tips for preventing and coping with osteoarthritis

Most everyone is bound to get osteoarthritis -- if they live long enough. That old saying among arthritis experts is backed up by the numbers. The painful and often debilitating joint condition is the most common form of arthritis.

9 Oct 2013

Moximed initiates pivotal trial of KineSpring System implantation in knee osteoarthritis patients

Moximed, Inc. announced today that the KineSpring® System, an implantable medical spring for knee osteoarthritis that works by unloading the weight on the diseased joint, has been successfully implanted in the first patients enrolled in the UK arm of its multi-centre GOAL study.

9 Oct 2013

Osteoarthritis and exercise: an interview with Dr Nicola Walsh, Associate Professor at the University of the West of England

Exercise helps to keep the surrounding muscles strong to protect the joint, and also reduces stiffness that people frequently experience in the morning or after periods of inactivity. Joints are meant to move, so keeping them mobile will assist with joint health, maintain range of movement and enhance stability.

7 Oct 2013

Scientists at Oklahoma Medical Research Foundation identify six new Sj-gren-related genes

With the completion of the first genome-wide association study for Sj-gren's syndrome, an international coalition of researchers led by scientists at the Oklahoma Medical Research Foundation has identified six new disease-related genes.

7 Oct 2013

Anti-inflammatory mechanism leads to development of oral medications for atherosclerosis, IBS

Research led by Charles Nichols, PhD, Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, describes a powerful new anti-inflammatory mechanism that could lead to the development of new oral medications for atherosclerosis and inflammatory bowel disorders (IBS).

7 Oct 2013

Researchers identify protein that triggers inflammation in patients with hemorrhage, sepsis

Investigators at The Feinstein Institute for Medical Research have discovered a protein in the human body that can trigger and mediate inflammation in patients suffering from hemorrhage and sepsis. The findings were published in the online version of Nature Medicine on October 6, 2013.

7 Oct 2013

AbbVie announces HUMIRA phase II study results for treating hidradenitis suppurativa

AbbVie (NYSE: ABBV) today announced results from a post-hoc analysis of an investigational Phase II study, which evaluated HUMIRA® (adalimumab) in the treatment of patients with moderate-to-severe hidradenitis suppurativa (HS) after 16 weeks of therapy.

7 Oct 2013

J&J's Janssen Companies Launch A Trio Of Collaborations

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3 Oct 2013

Arthritis News and Research

Latest Arthritis News and Research

FDA approves OTREXUP injection for adults with RA, children with active pJIA

Genentech plans to invest over $285M for expansion of biologics manufacturing facilities

Scientists develop new method to regenerate cartilage

Crucial role of orthopedic surgeons in diagnosing mTBI among trauma care patients

Finding highlights new ways of treating inflammation disorders

Drugs often fail to bring acromegaly under control in routine clinical practice

Pfizer reports positive results from two tofacitinib Phase 3 trials for chronic plaque psoriasis

TSRI scientists identify set of compounds to treat multiple sclerosis in new way

Research points to causes, potential treatment approaches for systemic sclerosis

Dry eye disease symptom change independent of tear osmolarity

Lakewood-Amedex, Wainwright enter into strategic advisory agreement

Compugen drug candidate prevents autoimmune type I diabetes in animal model

Experts offer tips for preventing and coping with osteoarthritis

Moximed initiates pivotal trial of KineSpring System implantation in knee osteoarthritis patients

Osteoarthritis and exercise: an interview with Dr Nicola Walsh, Associate Professor at the University of the West of England

Scientists at Oklahoma Medical Research Foundation identify six new Sj-gren-related genes

Anti-inflammatory mechanism leads to development of oral medications for atherosclerosis, IBS

Researchers identify protein that triggers inflammation in patients with hemorrhage, sepsis

AbbVie announces HUMIRA phase II study results for treating hidradenitis suppurativa

J&J's Janssen Companies Launch A Trio Of Collaborations

Pharmaceutical Manufacturing - Industry Focus eBook eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

Arthritis News and Research

Latest Arthritis News and Research

Pharmaceutical Manufacturing - Industry Focus eBook eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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