Arthritis News and Research

Latest Arthritis News and Research

CD4 T cells orchestrate inflammatory attack on the artery wall

Most people probably know that heart disease remains the nation's No. 1 killer. But what many may be surprised to learn is that cholesterol has a major accomplice in causing dangerous arterial plaque buildup that can trigger a heart attack. The culprit? Inflammatory cells produced by the immune system.

15 Aug 2012

Cathepsins may attack one another instead of the bodily proteins

Researchers for the first time have shown that members of a family of enzymes known as cathepsins - which are implicated in many disease processes - may attack one another instead of the bodily proteins they normally degrade. Dubbed "cathepsin cannibalism," the phenomenon may help explain problems with drugs that have been developed to inhibit the effects of these powerful proteases.

15 Aug 2012

New class of drugs may prove useful in treating cancer and aging-associated disorders

In a study published in the Proceedings of the National Academy of Sciences (PNAS) on Aug. 6, an international team led by Igor Roninson, of the University of South Carolina and the Medical University of South Carolina, reported the development of a new class of drugs that may prove useful in the treatment of cancer and aging-associated disorders.

14 Aug 2012

Tofacitinib efficacy suggested for rheumatoid arthritis

The novel oral Janus kinase inhibitor tofacitinib significantly reduces signs and symptoms of rheumatoid arthritis, report two phase III trials published in TheNew England Journal of Medicine.

13 Aug 2012

Twelve states currently have adult obesity rate above 30%

Twelve states currently have an adult obesity rate above 30 percent, according to a new analysis released today by the Trust for America's Health (TFAH) and the Robert Wood Johnson Foundation (RWJF).

13 Aug 2012

Promising stem cell therapy may prevent osteoarthritis after joint injury

Duke researchers may have found a promising stem cell therapy for preventing osteoarthritis after a joint injury.

10 Aug 2012

Longer looks: Waking up to the need for sleep

Among the more than 11,000 dearly departed inhabitants of Southeast Portland's Multnomah Park Cemetery, friends Eric Cordingley and David Anderson have their favorites: a reputed French madam, a young Norwegian institutionalized for being gay, and Louis Napoleon Lepley -- or, as they call him, "Louis the cannibal." Intriguing as their individual stories may be, together they help tell a bigger, darker tale

10 Aug 2012

Internet poor for foot and ankle patients

Foot and ankle patients seeking education on the internet are likely to come across poor quality information on their diagnosis, US researchers warn.

9 Aug 2012

Amgen announces decision to stop ganitumab Phase 3 trial in advanced pancreatic cancer

Amgen today announced a decision to stop the ganitumab (AMG 479) Phase 3 GAMMA (Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas) trial following the recommendation of an independent Data Monitoring Committee (DMC) overseeing the trial.

9 Aug 2012

Study compares mortality rates among RA patients treated with individual TNF inhibitors

New research confirms no significant difference in the rates of death among patients with rheumatoid arthritis (RA) who were exposed to one of several TNF inhibitors used to treat RA, adalimumab (Humira), etanercept (Enbrel), and infliximab (Remicade).

8 Aug 2012

New class of drugs reduces adverse effects of cellular damage from cancer chemotherapy

Chemotherapy kills tumor cells, but it also wreaks havoc on the rest of the body. A team of researchers led by Igor Roninson of the South Carolina College of Pharmacy just reported the discovery of a new class of drugs that reduces the adverse effects of cellular damage from chemotherapy.

8 Aug 2012

Dental health linked to falls in Japanese elderly

Japanese study results indicate that elderly individuals with 19 or fewer teeth who do not wear dentures are at a greater risk for incident falls than their counterparts with 20 teeth or more.

7 Aug 2012

Cardiovascular risk present across chronic rheumatic diseases

Patients across the spectrum of rheumatic diseases, not just those with rheumatoid arthritis, have a significantly increased prevalence of cardiovascular risk factors compared with the general population, the results of a Dutch study indicate.

6 Aug 2012

TWi Pharmaceuticals completes AC-201 phase II study on type II diabetes

TWi Pharmaceuticals, Inc., a specialty pharmaceutical company based in Taiwan, today announced its fully owned subsidiary, TWi Biotechnology, Inc. has completed a multinational phase II dose-ranging study of AC-201, an orally available IL-1 Beta modulator, in 259 patients with type II diabetes uncontrolled on up to three oral medications.

6 Aug 2012

Montefiore launches first fellowship program in Women's Physical Medicine and Rehabilitation

Montefiore Medical Center has launched the nation's first fellowship program in Women's Physical Medicine and Rehabilitation (WPM&R), and established a new clinical program in this specialty.

6 Aug 2012

Research roundup: Massachusetts health reform; Role of race and insurance in kidney transplantation

Access to Care After Massachusetts' Health Care Reform: A Safety Net Hospital Patient Survey -- Policy analysts have long said that Massachusetts and its 2006 health reform law provide great insight into the federal health law and how its expansion of insurance coverage will play out.

3 Aug 2012

3D scanner can identify early foot deformity in RA patients

Researchers report that a digital 3D foot scanner can detect foot deformities in patients with rheumatoid arthritis, even before clinical signs are present.

2 Aug 2012

Most incidences of shoulder joint instability are due to traumatic contact injuries

Summer is a peak season for many sports, and with that comes sport-related injuries. Among those injuries is shoulder joint dislocation. According to a literature review in the August 2012 issue of the Journal of the American Academy of Orthopaedic Surgeons, most incidences of shoulder joint instability are the result of traumatic contact injuries like force or falling on an outstretched arm; a direct blow to the shoulder area; forceful throwing, lifting or hitting; or contact with another player.

2 Aug 2012

Exactech second quarter revenue increases 7% to $55.2 million

Exactech, Inc., a developer and producer of bone and joint restoration products for hip, knee, shoulder, spine and biologic materials, announced today revenue of $55.2 million for the second quarter of 2012, a 7% increase over $51.7 million in the second quarter of 2011.

31 Jul 2012

Array BioPharma announces positive results from ARRY-797 Phase 2 trial on osteoarthritis

Array BioPharma today announced that ARRY-797 met its primary endpoint in a randomized, placebo-controlled and active-controlled (oxycodone ER) Phase 2 clinical trial in 157 osteoarthritis patients suffering from moderate to severe knee pain despite the use of non-steroidal anti-inflammatory drugs (NSAIDs).

31 Jul 2012

Arthritis News and Research

Latest Arthritis News and Research

CD4 T cells orchestrate inflammatory attack on the artery wall

Cathepsins may attack one another instead of the bodily proteins

New class of drugs may prove useful in treating cancer and aging-associated disorders

Tofacitinib efficacy suggested for rheumatoid arthritis

Twelve states currently have adult obesity rate above 30%

Promising stem cell therapy may prevent osteoarthritis after joint injury

Longer looks: Waking up to the need for sleep

Internet poor for foot and ankle patients

Amgen announces decision to stop ganitumab Phase 3 trial in advanced pancreatic cancer

Study compares mortality rates among RA patients treated with individual TNF inhibitors

New class of drugs reduces adverse effects of cellular damage from cancer chemotherapy

Dental health linked to falls in Japanese elderly

Cardiovascular risk present across chronic rheumatic diseases

TWi Pharmaceuticals completes AC-201 phase II study on type II diabetes

Montefiore launches first fellowship program in Women's Physical Medicine and Rehabilitation

Research roundup: Massachusetts health reform; Role of race and insurance in kidney transplantation

3D scanner can identify early foot deformity in RA patients

Most incidences of shoulder joint instability are due to traumatic contact injuries

Exactech second quarter revenue increases 7% to $55.2 million

Array BioPharma announces positive results from ARRY-797 Phase 2 trial on osteoarthritis

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Arthritis News and Research

Latest Arthritis News and Research

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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