CRISPR News and Research

Latest CRISPR News and Research

Many patients may not benefit from gene-editing treatments for sickle cell disease

Federal approval of a breakthrough gene-editing technology that treats the pain and debilitating effects of sickle cell disease is cause for celebration among a community with few options for relief.

8 Dec 2023

New discovery unveils an additional layer of the CRISPR-Cas antiviral defense system

The recent publication in Science by Mogila, Tamulaitiene et al. represents a continuation of the successful scientific research conducted by Gintautas Tamulaitis' group.

4 Dec 2023

Breakthrough in Malaria detection: new FREM platform delivers 98% accuracy for rapid screening and genotyping

The Flexible, Robust, Equipment-free Microfluidic (FREM) platform for malaria screening and Plasmodium species genotyping.

1 Dec 2023

New study provides convincing evidence of the essential role of cylicins in sperm development and fertility

Researchers investigated the Role of Cylicins in Spermiogenesis and Male Fertility in Mice and Humans through Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/ CRISPR-associated protein 9 (Cas9) Gene Editing.

30 Nov 2023

Researchers introduce CRISPR-mediated genome and cancer shredding as a conceptual paradigm to treat recurrent gliomas

Researchers demonstrated clustered regularly interspersed short palindromic repeats (CRISPR)-mediated elimination of glioblastoma (GBM) cells.

29 Nov 2023

Missing protein triggers alternative immune attack on cancer cells

Researchers at the UCLA Jonsson Comprehensive Cancer Center have found certain immune cells can still fight cancer even when the cancer cells lack an important protein that the immune system relies on to help track down cancer cells.

28 Nov 2023

Study finds diet-derived trans-vaccenic acid boosts anti-tumor immunity

Dietary components that impact anti-tumor immunity.

28 Nov 2023

Synthetic biologists develop versatile platform for targeted drug delivery

In recent years, cell and gene therapies have shown significant promise for treating cancer, cystic fibrosis, diabetes, heart disease, HIV/AIDS and other difficult-to-treat diseases.

27 Nov 2023

New stem cell-based treatment for Type 1 diabetes can reduce dependence on daily insulin injections

An innovative stem cell-based treatment for Type 1 diabetes can meaningfully regulate blood glucose levels and reduce dependence on daily insulin injections, according to new clinical trial results from the University of British Columbia (UBC) and Vancouver Coastal Health (VCH).

27 Nov 2023

SECRE technique paves way for new therapeutics for autoimmune diseases

Scientists have developed a potentially transformative new technique that could aid in the discovery and development of new therapeutics for a number of globally prevalent autoimmune diseases.

27 Nov 2023

New CRISPR approach shows promise for treating glioblastoma

The gene-editing technology CRISPR shows early promise as a therapeutic strategy for the aggressive and difficult-to-treat brain cancer known as primary glioblastoma, according to findings of a new study from Gladstone Institutes.

27 Nov 2023

Bonn immunologist receives €2 million grant to harness the power of nanobodies for inflammation control

Bonn immunologist Prof. Florian I. Schmidt, who conducts research at the Institute of Innate Immunity at the University Hospital Bonn (UKB), has been awarded a Consolidator Grant from the European Research Council to fund his research project DEFLAMMATION with two million Euro.

23 Nov 2023

Scientists uncover key to enhancing cancer-killing T cells

T cells are the key immune system component involved in killing cancer. Tumors produce signals that turn off these T cells, partially by forcing them to progressively differentiate (mature) into a hypofunctional state known as exhaustion.

21 Nov 2023

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

The R136S genetic mutation protected against apolipoprotein E4 (APOE4)-induced late-onset Alzheimer’s disease (LOAD).

16 Nov 2023

Bacteria fight phages with RNA-based immune defense

There's no organism on earth that lives free of threat-;including bacteria. Predatory viruses known as phages are among their most dire foes, infiltrating their cells to replicate and take over.

15 Nov 2023

New approach to CAR T cell therapy may extend treatment effectiveness

CAR T cell therapy, a powerful type of immunotherapy, has begun to revolutionize cancer treatment. Pioneered at Memorial Sloan Kettering Cancer Center (MSK), the therapy involves engineering a patient's T cells so they recognize and attack cancer cells.

14 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

A single infusion of a CRISPR-based gene-editing therapy significantly reduced low-density lipoprotein cholesterol (LDL, the "bad cholesterol") in people who carry one gene for the inherited condition that results in very high LDL cholesterol levels and a high risk of heart attack at an early age, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Research explores the advancements, challenges, and economic implications of gene therapy for various diseases, including inherited blood disorders, malignancies treated with CAR-T cells, and diseases targeted by in vivo AAV vectors. The review highlights the transformative potential of gene therapies while acknowledging the complexities in manufacturing, safety, efficacy, and long-term durability.

12 Nov 2023

Time-lapsed images show how magnesium ions coordinate double-stranded breaks in CRISPR-Cas9

The gene-editing technology known as CRISPR has led to revolutionary changes in agriculture, health research and more.

2 Nov 2023

CRISPR News and Research

Latest CRISPR News and Research

Many patients may not benefit from gene-editing treatments for sickle cell disease

New discovery unveils an additional layer of the CRISPR-Cas antiviral defense system

Breakthrough in Malaria detection: new FREM platform delivers 98% accuracy for rapid screening and genotyping

New study provides convincing evidence of the essential role of cylicins in sperm development and fertility

Researchers introduce CRISPR-mediated genome and cancer shredding as a conceptual paradigm to treat recurrent gliomas

Missing protein triggers alternative immune attack on cancer cells

Study finds diet-derived trans-vaccenic acid boosts anti-tumor immunity

Synthetic biologists develop versatile platform for targeted drug delivery

New stem cell-based treatment for Type 1 diabetes can reduce dependence on daily insulin injections

SECRE technique paves way for new therapeutics for autoimmune diseases

New CRISPR approach shows promise for treating glioblastoma

Bonn immunologist receives €2 million grant to harness the power of nanobodies for inflammation control

Scientists uncover key to enhancing cancer-killing T cells

Rare APOE3-R136S mutation offers protection against Alzheimer's disease pathologies in new study

Bacteria fight phages with RNA-based immune defense

New approach to CAR T cell therapy may extend treatment effectiveness

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Time-lapsed images show how magnesium ions coordinate double-stranded breaks in CRISPR-Cas9

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut