CRISPR News and Research

Latest CRISPR News and Research

Study confirms the implication of Mib1 mutations in non-compaction cardiomyopathy

Non-compaction cardiomyopathy is a heart condition caused by defects that arise during fetal development and can have diverse health impacts in affected individuals, including sudden cardiac death.

7 Nov 2022

Study finds possible treatment strategy for Feingold syndrome type 1

A decrease in protein synthesis in cells of the developing gut contributes to a rare genetic disorder, and an inexpensive nutritional supplement may help reverse that decrease, according to a new study publishing November 1st in the open access journal PLOS Biology by Yun-Fei Li of Zhejiang University School of Medicine in Hangzhou, China, and colleagues. The finding is an advance in understanding the pathogenesis of the disease, and may lead to new treatments.

2 Nov 2022

New control system could be used to finely tune the production of useful proteins

Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.

1 Nov 2022

Specific stem cell protein found to be involved in the recurrence of medulloblastoma

The malignant brain tumor type medulloblastoma can become resistant to therapy which can cause relapse. Researchers at Uppsala University have discovered a certain protein that makes tumor cells resting and insensitive to radiation treatment.

28 Oct 2022

Yeast reveals a key mechanism in how genes are controlled

Yeast, that simple organism essential to making beer and bread, has revealed for Cornell University researchers a key mechanism in how genes are controlled.

28 Oct 2022

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill children with resistant leukaemia, who had otherwise exhausted all available therapies.

27 Oct 2022

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a protein of interest in response.

27 Oct 2022

Discovery points to a new understanding of Stargardt disease progression

Using a new stem-cell-based model made from skin cells, scientists found the first direct evidence that Stargardt-related ABCA4 gene mutations affect a layer of cells in the eye called the retinal pigment epithelium (RPE).

27 Oct 2022

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

A fault in cells that form a key part of the immune system can be repaired with a pioneering gene editing technique, finds new research demonstrated in human cells and mice, led by UCL scientists.

27 Oct 2022

New studies point to a broadly applicable treatment for neurodegenerative diseases

Two new studies from Washington University School of Medicine in St. Louis support development of a broadly applicable treatment for neurodegenerative diseases that targets a molecule that serves as the central executioner in the death of axons, the wiring of the nervous system.

26 Oct 2022

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Impaired DNA repair capacity among elderly increases expression of ACE2 receptor.

26 Oct 2022

Researchers set sights on a new therapeutic target for aggressive breast cancer

Researchers at VCU Massey Cancer Center have set their sights on a new therapeutic target for an aggressive form of breast cancer with limited treatment options.

25 Oct 2022

Celebrating the Alderley Park Grand Opening

HQ Plasmid Center of Excellence based at UK life science hotspot now open for business.

From Charles River Laboratories, Inc. 24 Oct 2022

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

In a new study, researchers introduced a compact rapid detection kit that tests for the monkeypox virus using a combination of RPA and CRISPR technology.

24 Oct 2022

Butterfly wing pattern ground plan is manipulated by non-coding regulatory DNA, study says

Butterfly wing patterns have a basic plan to them, which is manipulated by non-coding regulatory DNA to create the diversity of wings seen in different species, according to new research.

21 Oct 2022

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Mitochondria -; the organelles responsible for energy production in human cells -; were once free-living organisms that found their way into early eukaryotic cells over a billion years ago.

20 Oct 2022

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

In a recent study published in the journal Nature Cell Biology, researchers demonstrated the susceptibility of salivary glands to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in vitro using an organoid culture model.

20 Oct 2022

Study identifies genetic variation that influences lithium-induced neural proliferation

Bipolar disorder, a neuropsychiatric condition that includes manic and depressive episodes, affects about 1% of the population and is strongly influenced by genetics.

18 Oct 2022

On-site ultrasensitive monkeypox viral testing using CRISPR/Cas12a

In a new study posted to the medRxiv* preprint server, researchers in China developed an MPXV assay combining clustered regularly interspaced short palindromic repeats and CRISPR-associated protein (CRISPR/Cas) and recombinase-aided amplification (RAA) for the first time.

18 Oct 2022

Transition in the management of COVID-19

A review of the current approaches to managing COVID-19, including diagnostic, therapeutic, and preventive measures.

16 Oct 2022

CRISPR News and Research

Latest CRISPR News and Research

Study confirms the implication of Mib1 mutations in non-compaction cardiomyopathy

Study finds possible treatment strategy for Feingold syndrome type 1

New control system could be used to finely tune the production of useful proteins

Specific stem cell protein found to be involved in the recurrence of medulloblastoma

Yeast reveals a key mechanism in how genes are controlled

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia

RNA-sensing platform could help detect and selectively kill tumors, or edit the genome in specific cells

Discovery points to a new understanding of Stargardt disease progression

Pioneering gene editing technique can repair faulty T cells in patients with CTLA-4 insufficiency

New studies point to a broadly applicable treatment for neurodegenerative diseases

DNA damage in older age increases expression of ACE2 and SARS-CoV-2 infection risk

Researchers set sights on a new therapeutic target for aggressive breast cancer

Celebrating the Alderley Park Grand Opening

Compact rapid detection kit to test for monkeypox virus shows promising results in new research

Butterfly wing pattern ground plan is manipulated by non-coding regulatory DNA, study says

MTCH2 acts as a doorway for proteins into the mitochondrial membrane, study reveals

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

Study identifies genetic variation that influences lithium-induced neural proliferation

On-site ultrasensitive monkeypox viral testing using CRISPR/Cas12a

Transition in the management of COVID-19

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

Bridging the Gap between Academia and Industry: The Power of Collaboration in Life Sciences