CRISPR News and Research

Latest CRISPR News and Research

mRNA Therapeutics – Analytical and Bioanalytical Characterization

NewsMed interviews Anette Bak from AstraZeneca about her research on developments in mRNA therapeutics that she will present at Pittcon 2021.

From Pittcon 23 Feb 2021

DNA origami used to analyze the ultra-fast movements of CRISPR enzymes

The remarkable genetic scissors called CRISPR/Cas9, the discovery that won the 2020 Nobel Prize in Chemistry, sometimes cut in places that they are not designed to target.

23 Feb 2021

Researchers investigate how CF patients respond to COVID-19

So far, based on clinical data, patients with cystic fibrosis (CF) don't appear to be especially susceptible to COVID-19, and when they do get infected, they don't seem to get sicker. But Ruobing (Ruby) Wang, MD, a physician-scientist in the Division of Pulmonary Medicine at Boston Children's Hospital, cares for patients with CF and thinks there is more to the story.

23 Feb 2021

Researchers find a way to improve deletion efficiency of new genome-editing tool

CRISPR deletion (CRISPR-del) is a new genome editing tool that can delete or cut out certain pieces of DNA in living cells with surgical precision.

17 Feb 2021

Researchers identify molecular link between inflammatory signaling molecule and a main oncogene

A team of MedUni Vienna researchers led by Johannes A. Schmid at the Center for Physiology and Pharmacology, Institute of Vascular Biology and Thrombosis Research, has managed to identify a previously unknown molecular connection between an inflammatory signaling molecule and one of the main oncogenes.

17 Feb 2021

ERS Genomics and ZeClinics sign CRISPR/Cas9 license agreement

ERS Genomics Limited, which was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property co-owned by Dr. Emmanuelle Charpentier, and ZeClinics, a contract research organization using zebrafish to carry out services focused on analyzing the safety, efficacy and biomedical relevance of new compounds, today announced a non-exclusive license agreement granting ZeClinics access to ERS Genomics’ CRISPR/Cas9 patent portfolio.

From ZeClinics SL 16 Feb 2021

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

A new preprint research paper posted to the bioRxiv server provides a greater understanding of the aspect of humoral immunity against the virus – the plasma cells that pour out a flood of specific antibodies targeting various epitopes on the pathogen.

16 Feb 2021

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

As a professor of pediatrics and cellular and molecular medicine at University of California San Diego School of Medicine, Alysson R. Muotri, PhD, has long studied how the brain develops and what goes wrong in neurological disorders.

15 Feb 2021

Scientists discover new immunotherapy target for malignant brain tumors

Scientists say they have discovered a potential new target for immunotherapy of malignant brain tumors, which so far have resisted the ground-breaking cancer treatment based on harnessing the body's immune system.

15 Feb 2021

RIG-1-like receptors may play dominant role in suppressing SARS-CoV-2 infection

A new study by researchers at the University of Connecticut Health Center, USA, reports the crucial nature of the pathogen pattern recognition receptor (PRRs), especially the two RLRs, retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated protein 5 (MDA5), in triggering host cell immune responses within the cell. The RLRs are viral RNA sensors.

15 Feb 2021

Webinar: High-Content Imaging on Human Pluripotent Stem Cell Research

The upcoming webinar 'Visualizing Human Stem Cell Dynamics by Multicolor, Multiday High-Content Microscopy' will take place on February 17, 11 AM EST / 5 PM CET.

From Yokogawa Electric Corporation 12 Feb 2021

Freiburg immunologists decipher anti-cancer drug's mode of operation

Rituximab, an anti-cancer drug targeting the membrane protein CD20, was the first approved therapeutic antibody against B tumor cells. Immunologists at the University of Freiburg have now solved a mystery about how it works.

10 Feb 2021

Researchers identify top-performing COVID-19 POC tests

After screening more than 1,100 independently assessed, point-of-care COVID-19 tests, researchers at NSF International and Novateur Ventures have identified 5 direct (antigen/RNA) tests for detection of acute infection and 6 indirect (antibody) tests for detection of prior infection that meet the recently published World Health Organization (WHO) "desirable" Target Product Profile (TPP) criteria.

10 Feb 2021

Modified CRISPR/Cas9 complex targets specific histones

Finding a needle in a haystack is hard enough. But try finding a specific molecule on the needle.

9 Feb 2021

CRISPR genomic editing to obtain more productive and nutritive plant varieties

New study by the IBMCP of the UPV university facilitates the use of the CRISPR genomic editing technique on plants.

8 Feb 2021

Study implicates disruption in prenatal neurogenesis in the development of ASDs

A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis - a process in which specialized "progenitor" cells give rise to new brain cells - in the development of autism spectrum disorders (ASDs).

8 Feb 2021

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

A new study by researchers at the University of Manchester, UK, reports on the compounds of interest that were identified as having potential for the treatment of COVID-19, from a library of almost 2,000 compounds from the APExBIO DiscoveryProbe library.

3 Feb 2021

CRISPR News and Research

Latest CRISPR News and Research

mRNA Therapeutics – Analytical and Bioanalytical Characterization

DNA origami used to analyze the ultra-fast movements of CRISPR enzymes

Researchers investigate how CF patients respond to COVID-19

Researchers find a way to improve deletion efficiency of new genome-editing tool

Researchers identify molecular link between inflammatory signaling molecule and a main oncogene

ERS Genomics and ZeClinics sign CRISPR/Cas9 license agreement

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

Scientists study how a single gene alteration may have separated modern humans from extinct hominins

Scientists discover new immunotherapy target for malignant brain tumors

RIG-1-like receptors may play dominant role in suppressing SARS-CoV-2 infection

Webinar: High-Content Imaging on Human Pluripotent Stem Cell Research

Freiburg immunologists decipher anti-cancer drug's mode of operation

Researchers identify top-performing COVID-19 POC tests

Modified CRISPR/Cas9 complex targets specific histones

CRISPR genomic editing to obtain more productive and nutritive plant varieties

Study implicates disruption in prenatal neurogenesis in the development of ASDs

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

New method identifies important mutations behind hereditary non-polyposis colorectal cancer

Study: TALEN is five times more efficient than CRISPR-Cas9 in tightly packed DNA

Researchers identify foods that cause 90% of food allergies

Mastering plasmid production for genetic engineering and therapeutic research eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?