Cancer News and Research

Latest Cancer News and Research

Open source machine learning tools as good as humans in detecting cancer cases

Machine learning has come of age in public health reporting according to researchers from the Regenstrief Institute and Indiana University School of Informatics and Computing at Indiana University-Purdue University Indianapolis.

22 Apr 2016

U of M to present session on Canine and Human Epilepsy at iCOMOS

As part of the International Conference on One Medicine One Science taking place April 24-27, the University of Minnesota will present a session on Canine and Human Epilepsy on April 27.

22 Apr 2016

PPP3CA, calcineurin may be suitable therapeutic targets for multiple myeloma treatment

Multiple myeloma (MM) is a hematological cancer that frequently acquires resistance to chemotherapeutic drugs. Additionally, many patients experience disease relapse, but these patients are difficult to treat as the cancer is often resistant to the previous treatment regimen.

22 Apr 2016

Scientists examine PD-1-expressing regulatory T cells in aggressive brain cancer

Immunotherapy represents an exciting advance in cancer treatment that harnesses the immune system to seek and destroy cancer cells.

22 Apr 2016

Study paves way for refining antibody-based cancer immunotherapy

A study coordinated by the Malmberg Laboratory at Oslo University Hospital/University of Oslo and the Karolinska Institute, published in Cell Reports, reveals a molecule that trigger cancer recognition in natural killer (NK) cells.

22 Apr 2016

Bosutinib shows 'low' vascular, cardiac event risk profile

Third-generation tyrosine kinase inhibitor study findings suggest that bosutinib is associated with a low risk of vascular and cardiac events in patients undergoing first-line or subsequent treatment for chronic myeloid leukaemia.

21 Apr 2016

Novel combination of cancer drugs can have therapeutic impact on diffuse large B-cell lymphoma

New research from Roswell Park Cancer Institute shows that promising cancer drugs used in combination can have significant therapeutic impact on a particularly aggressive subtype of diffuse large B-cell lymphoma (DH-DLBCL) in preclinical studies. The researchers will present their findings at the American Association for Cancer Research (AACR) Annual Meeting 2016, to be held April 16-20 in New Orleans.

21 Apr 2016

New study explores mechanisms that control size, shape of tubular organ systems

A new study from the group of Holger Gerhardt in collaboration with Katie Bentley's Lab addresses a long standing question in the wider field of developmental biology and tissue patterning in general, and in the vascular biology field in particular: 'What are the fundamental mechanisms controlling size and shape of tubular organ systems'.

21 Apr 2016

Scientists develop CRISPRainbow to study genome structure in real time

CRISPRainbow, a new technology using CRISPR/Cas9 developed by scientists at UMass Medical School, allows researchers to tag and track up to seven different genomic locations in live cells. This labeling system, details of which were published in Nature Biotechnology, will be an invaluable tool for studying the structure of the genome in real time.

21 Apr 2016

Hippo signaling pathway controls phases of quiescence in fruit fly central nervous system

Neural stem cells are responsible for the formation of differentiated daughter cells in the developing brain. If no new cells are needed, the stem cells may enter a resting phase called quiescence. Biologists at Johannes Gutenberg University Mainz have now discovered that the phases of quiescence in the Drosophila fruit fly central nervous system are controlled by the Hippo signaling pathway. Drosophila serves as a model organism that helps geneticists to decode the molecular fundamentals of cellular biology and unravel mechanisms that are conserved in human beings and other vertebrates.

21 Apr 2016

Exhaled e-cigarette vapour evaporates within seconds

A new study being presented today at the 4th Workplace and Indoor Aerosols conference in Barcelona shows, for the first time, that exhaled e-cigarette particles are liquid droplets that evaporate within seconds.

21 Apr 2016

SI-2 molecule can inhibit tumor growth in breast cancer mouse model

Cancer cells communicate with their environment through cell molecules that pass on signals to the inside of the cell. The signals help cancer cells multiply and migrate, spreading the disease.

21 Apr 2016

Researchers find new insights on disease stages for gastric cancer patients

Diagnosis of gastric cancer in the early stages is difficult because of the lack of simple and cheap methods of inspection and specific markers of gastric cancer while the symptoms of the disease are vague and tend to overlap with other common and benign conditions. Better tumor characterization and more individualized treatment planning can be expected only with the implementation of better diagnostic tools combined with advances in molecular and genetic analysis.

21 Apr 2016

Better way to model human immune system

Scientists at the University of Minnesota have developed a new way to study mice that better mimics the immune system of adult humans and which could significantly improve ways to test potential therapeutics. Published online today in the journal Nature, the researchers describe the limitations of laboratory mice for immunology research and reveal the benefits of what they are calling "dirty mice."

21 Apr 2016

Drugs that block NOTCH signaling in many cancers could be effective against ACC

Using a novel cell culture approach, Yale Cancer Center researchers have discovered critical vulnerabilities in adenoid cystic carcinoma (ACC), a rare and lethal glandular cancer with a high recurrence rate and few treatment options.

21 Apr 2016

Scientists uncover unique cellular defects linked with SLOS using novel stem-cell model

Studies performed by a Sanford Research scientist using an innovative stem-cell model for a fatal developmental disorder is the focus of a recent study published in Nature Medicine. Kevin Francis, Ph.D. uncovered unique cellular defects associated with Smith-Lemli-Opitz syndrome (SLOS) by modeling this disease using induced pluripotent stem cells.

21 Apr 2016

Clinical study shows watercress extract inhibits carcinogen activation in cigarette smokers

Watercress extract taken multiple times a day significantly inhibits the activation of a tobacco-derived carcinogen in cigarette smokers, researchers at the University of Pittsburgh Cancer Institute, partner with UPMC Cancer Center, demonstrated in a phase II clinical trial presented today at the American Association for Cancer Research Annual Meeting in New Orleans.

21 Apr 2016

Researchers reposition existing prazosin drug to combat glioblastoma

Treatments available for glioblastoma—malignant brain tumors—have little effect. An international collaboration led by the Laboratoire Neurosciences Paris-Seine tested active ingredients from existing medications and eventually identified one compound of interest, prazosin, on these tumors. Not only did it seem to be effective in this type of cancer, but it also acted on a signaling pathway that is common with other cancers.

21 Apr 2016

Multivitamin use prior to diagnosis may reduce effects of CIPN in breast cancer survivors

Researchers at Roswell Park Cancer Institute, in collaboration with investigators from the cooperative group SWOG, have found that use of multivitamins prior to diagnosis may reduce the risk of neuropathy in breast cancer patients treated with the class of drugs known as taxanes. The team will present their findings at the American Association for Cancer Research Annual Meeting 2016, to be held April 16-20 in New Orleans.

21 Apr 2016

Novel method could help analyze GWAS results for sporadic diseases

Using a novel method, Whitehead Institute researchers have determined how a non-coding mutation identified in genome-wide association studies can contribute to sporadic Parkinson's disease (PD). The approach could be used to analyze GWAS results for other sporadic diseases with genetic causes, such as multiple sclerosis, diabetes, and cancer.

21 Apr 2016

Cancer News and Research

Latest Cancer News and Research

Open source machine learning tools as good as humans in detecting cancer cases

U of M to present session on Canine and Human Epilepsy at iCOMOS

PPP3CA, calcineurin may be suitable therapeutic targets for multiple myeloma treatment

Scientists examine PD-1-expressing regulatory T cells in aggressive brain cancer

Study paves way for refining antibody-based cancer immunotherapy

Bosutinib shows 'low' vascular, cardiac event risk profile

Novel combination of cancer drugs can have therapeutic impact on diffuse large B-cell lymphoma

New study explores mechanisms that control size, shape of tubular organ systems

Scientists develop CRISPRainbow to study genome structure in real time

Hippo signaling pathway controls phases of quiescence in fruit fly central nervous system

Exhaled e-cigarette vapour evaporates within seconds

SI-2 molecule can inhibit tumor growth in breast cancer mouse model

Researchers find new insights on disease stages for gastric cancer patients

Better way to model human immune system

Drugs that block NOTCH signaling in many cancers could be effective against ACC

Scientists uncover unique cellular defects linked with SLOS using novel stem-cell model

Clinical study shows watercress extract inhibits carcinogen activation in cigarette smokers

Researchers reposition existing prazosin drug to combat glioblastoma

Multivitamin use prior to diagnosis may reduce effects of CIPN in breast cancer survivors

Novel method could help analyze GWAS results for sporadic diseases

Cancer Research - Second Edition eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

Cancer News and Research

Latest Cancer News and Research

Cancer Research - Second Edition eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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