Chromosome News and Research

Latest Chromosome News and Research

Study: More than 70% of bladder tumors display somatic mutations in TERT gene

Researchers from the Spanish National Cancer Research Centre (CNIO) have discovered that more than 70% of bladder tumours display somatic mutations in the TERT gene (telomerase reverse transcriptase).

11 Sep 2013

Researchers discover inherited gene mutation linked to childhood leukemia

Researchers have discovered the first inherited gene mutation linked exclusively to acute lymphoblastic leukemia occurring in multiple relatives in individual families. The discovery of the PAX5 gene mutation was led by St. Jude Children's Research Hospital and others. The work appears in the current advance online edition of the scientific journal Nature Genetics.

11 Sep 2013

Biologists identify two pathways via which chromosomes are rearranged

Biologists reported today in Nature that they have identified two pathways through which chromosomes are rearranged in mammalian cells. These types of changes are associated with some cancers and inherited disorders in people.

10 Sep 2013

Scientists develop strain of MERS-CoV that can be used as vaccine against disease

Scientists have developed a strain of the Middle East respiratory syndrome coronavirus (MERS-CoV) that could be used as a vaccine against the disease, according to a study to be published in mBio-, the online open-access journal of the American Society for Microbiology.

10 Sep 2013

Scientists find link between early-onset Parkinson's and 22q11.2 deletion syndrome

Scientists at the Centre for Addiction and Mental Health (CAMH) and University Health Network (UHN) have found a new link between early-onset Parkinson's disease and a piece of DNA missing from chromosome 22. The findings help shed new light on the molecular changes that lead to Parkinson's disease.

10 Sep 2013

Two Pathways Found Through Which Chromosomes Are Rearranged

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9 Sep 2013

International team of scientists discover new disease related to inability to process Vitamin B12

An international team of scientists, including University of Colorado School of Medicine and Children's Hospital Colorado researchers, has discovered a new disease related to an inability to process Vitamin B12.

6 Sep 2013

Elan enrolls first patient dosing in phase 2a study of ELND005 in Down syndrome

Elan Corporation, plc (NYSE: ELN) announced today the first patient dosing in a Phase 2a study of ELND005 in Down syndrome. Study ELND005-DS201 will evaluate the safety and pharmacokinetics of 2 doses of ELND005 and placebo in young adults with Down syndrome without dementia, and will also include select cognitive and behavioural measures.

5 Sep 2013

Research: Male sexual development less stable than other genetic programs

The idea that men and women are fundamentally different from each other is widely accepted. And throughout the world, this has created distinct ideas about which social and physical characteristics are necessary in each gender to maintain healthy human development.

3 Sep 2013

Scientists identify protein that blocks death of high-risk acute lymphoblastic leukemia cells

St. Jude Children's Research Hospital scientists have identified a protein that certain high-risk acute lymphoblastic leukemia (ALL) cells need to survive and have used that knowledge to fashion a more effective method of killing tumor cells. The findings appear in the August 29 edition of the journal Blood.

30 Aug 2013

Personality may be key to genetics of bipolar disorder

People with bipolar disorder vary significantly from their unaffected relatives, and from healthy controls, on several measures of personality, a study shows.

28 Aug 2013

Study shows ABL kinases have enhanced expression and activity in CML

Chronic Myelogenous Leukemia (CML) is a cancer of the white blood cells that is most commonly found in adults and in the elderly. Its incidence has been estimated to be 1 to 2 in 100,000 people. CML was the first cancer to be associated with a genetic abnormality, known as the Philadelphia Chromosome, which 95% of all CML patients carry in their cells.

28 Aug 2013

Researchers identify genetic locus associated with increased risk of CHD in type 2 diabetes patients

Researchers have identified a previously unknown genetic locus (the place a gene occupies on a chromosome) significantly associated with increased coronary heart disease risk among patients with type 2 diabetes, but the association was not found in individuals without diabetes, according to a study in the August 28 issue of JAMA.

28 Aug 2013

CeBiTec researchers successfully sequence genome of Chinese hamster

Genome researchers from Bielefeld University's Center for Biotechnology (CeBiTec) headed by Professor Dr. Alfred P-hler have succeeded in sequencing the genome of the Chinese hamster. The Chinese hamster supplies the cell cultures used by the pharmaceutical industry to produce biopharmaceutical products such as antibodies used in medicine.

26 Aug 2013

Scientists discover that chromosomal rearrangements can be advantageous

In a pioneer study published in the latest issue of the scientific journal Nature Communications, a research team at the Instituto Gulbenkian de Ci-ncia (IGC; Portugal), led by Miguel Godinho Ferreira in collaboration with Isabel Gordo, show for the first time that chromosomes rearrangements (such as inversions or translocations) can provide advantages to the cells that harbor them depending on the environment they are exposed.

23 Aug 2013

Clinical study to investigate effects of prenatal chromosomal abnormalities through microarray analysis

Reproductive genetics researchers at Columbia University Medical Center (CUMC) are leading a multicenter prospective clinical study investigating the effects of chromosomal abnormalities (duplicative or missing material) found prenatally through microarray analysis.

22 Aug 2013

Researchers identify gene that contributes to development of acute myeloid leukemia

Researchers at the University of Chicago Medicine Comprehensive Cancer Center (UCCCC) have identified a gene that contributes to the development of acute myeloid leukemia (AML). This pivotal finding follows 40 years of University of Chicago research that has slowly unraveled the genetic basis of leukemia.

21 Aug 2013

Children with gene amplification may require more aggressive treatment for ALL

A recent study by members of the Children's Oncology Group reports results of a large trial showing that children whose leukemia cells have amplification of a portion of chromosome 21 may require more aggressive treatment for Acute Lymphoblastic Leukemia (ALL) than children without this gene amplification.

21 Aug 2013

Researchers identify genome-wide locus for serious gastrointestinal condition in infants

Researchers have identified a new genome-wide significant locus (the place a gene occupies on a chromosome) for infantile hypertrophic pyloric stenosis (IHPS), a serious gastrointestinal condition associated with gastrointestinal obstruction, according to a study in the August 21 issue of JAMA. Characteristics of this locus also suggest the possibility of an inverse relationship between levels of circulating cholesterol in neonates and IHPS risk.

21 Aug 2013

Trinity researchers reveal CHD5 protein acts as tumor suppressor in nervous system development

CHD5 has previously been proposed as a tumour suppressor, acting as a brake that prevents healthy cells from developing into cancer cells. But the part played by the protein in healthy tissue, and whether this role is important for its ability to counter tumour growth, has remained largely uncharted.

14 Aug 2013

Chromosome News and Research

Latest Chromosome News and Research

Study: More than 70% of bladder tumors display somatic mutations in TERT gene

Researchers discover inherited gene mutation linked to childhood leukemia

Biologists identify two pathways via which chromosomes are rearranged

Scientists develop strain of MERS-CoV that can be used as vaccine against disease

Scientists find link between early-onset Parkinson's and 22q11.2 deletion syndrome

Two Pathways Found Through Which Chromosomes Are Rearranged

International team of scientists discover new disease related to inability to process Vitamin B12

Elan enrolls first patient dosing in phase 2a study of ELND005 in Down syndrome

Research: Male sexual development less stable than other genetic programs

Scientists identify protein that blocks death of high-risk acute lymphoblastic leukemia cells

Personality may be key to genetics of bipolar disorder

Study shows ABL kinases have enhanced expression and activity in CML

Researchers identify genetic locus associated with increased risk of CHD in type 2 diabetes patients

CeBiTec researchers successfully sequence genome of Chinese hamster

Scientists discover that chromosomal rearrangements can be advantageous

Clinical study to investigate effects of prenatal chromosomal abnormalities through microarray analysis

Researchers identify gene that contributes to development of acute myeloid leukemia

Children with gene amplification may require more aggressive treatment for ALL

Researchers identify genome-wide locus for serious gastrointestinal condition in infants

Trinity researchers reveal CHD5 protein acts as tumor suppressor in nervous system development

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

Chromosome News and Research

Latest Chromosome News and Research

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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