Chromosome News and Research

Latest Chromosome News and Research

Length of telomere may help determine prostate cancer patient's prognosis

Like the plastic caps at the end of shoelaces, telomeres protect — in their case — the interior-gene containing parts of chromosomes that carry a cell's instructional material. Cancer cells are known to have short telomeres, but just how short they are from cancer cell to cancer cell may be a determining factor in a prostate cancer patient's prognosis, according to a study led by Johns Hopkins scientists.

27 Sep 2013

Genomic instability in CFS is associated with less favorable outcome in patients with CaP

Detailed evaluation of a prostate cancer tumor biopsy may predict treatment outcomes for image-guided radiation therapy (IGRT) or surgery for prostate cancer, according to research presented today at the American Society for Radiation Oncology's (ASTRO's) 55th Annual Meeting.

27 Sep 2013

New imaging technique reveals first 3D pictures of chromosome structure

A new method for visualising chromosomes is painting a truer picture of their shape, which is rarely like the X-shaped blob of DNA most of us are familiar with.

27 Sep 2013

Researchers identify mutation in ITGA10 gene that causes chondrodysplasia in dog breeds

Professor Hannes Lohi's research group at the University of Helsinki and Folkhälsan Research Center has identified a mutation in ITGA10 gene, causing chondrodysplasia in two dog breeds, the Norwegian Elkhound and the Karelian Bear Dog.

26 Sep 2013

Research finds greater number of 'escaping genes' on X chromosome

Research from the University of Bath has found a greater number of 'escaping genes' on the X chromosome than have been previously detected, with implications for the understanding of mental impairment in humans.

26 Sep 2013

Inherited human herpesvirus 6 affects telomere stability and reactivates

Up to half a million people in Britain today may not know it, but in their genetic material they carry a particular form of herpesvirus 6 inherited from a parent.

21 Sep 2013

Comprehensive changes in lifestyle could reverse ageing

A pilot study, published in The Lancet Oncology, shows that comprehensive lifestyle changes may increase the length of telomeres, the ends of chromosomes that control cell ageing.

19 Sep 2013

Children with 22q11.2 deletion syndrome may often be misdiagnosed to have autism

Children with a genetic disorder called 22q11.2 deletion syndrome, who frequently are believed to also have autism, often may be misidentified because the social impairments associated with their developmental delay may mimic the features of autism, a study by researchers with the UC Davis MIND Institute suggests.

18 Sep 2013

Study shows that changes in diet, lifestyle choices may result in longer telomeres

A small pilot study shows for the first time that changes in diet, exercise, stress management and social support may result in longer telomeres, the parts of chromosomes that affect aging.

17 Sep 2013

Data can help scientists, physicians match precision drugs to cancer's genetic traits

More than 5,000 genetic profiles of tumor DNA have been completed in a large research study by scientists at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Boston Children's Hospital designed to speed the development of personalized cancer care with precision treatments.

13 Sep 2013

Findings may help explain why some diabetic women prone to develop kidney failure

A genetic variant on chromosome 2 is strongly linked with kidney failure in diabetic women but not in men, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

13 Sep 2013

Protein plays important role in process of degradation of tumour cells, say researchers

When tumour cells no longer degrade themselves, cancer may develop. Using black skin cancer as an example, Bern Researchers have now shown that a protein plays an important role in the process of degradation of tumour cells. By reactivating this degradation therapeutically, you can virtually force tumours to digest themselves.

12 Sep 2013

Dartmouth researchers find that protein cyclin A plays important role in cell division process

In a study to be published in the journal Nature, two Dartmouth researchers have found that the protein cyclin A plays an important but previously unknown role in the cell division process, acting as a master controller to ensure the faithful segregation of chromosomes during cell division.

12 Sep 2013

New research explains how DNA strands repair themselves

Researchers have discovered the details of how cells repair breaks in both strands of their DNA, a potentially devastating kind of DNA damage.

12 Sep 2013

Professor to develop DNA sequencing technologies to search for long-range genome interactions

Why do some people develop disease while others with the same genetic mutation don't? For example, the National Cancer Institute estimates that women who inherit a harmful BRCA2 mutation have a 45 percent chance of developing breast cancer by age 70.

11 Sep 2013

Study: More than 70% of bladder tumors display somatic mutations in TERT gene

Researchers from the Spanish National Cancer Research Centre (CNIO) have discovered that more than 70% of bladder tumours display somatic mutations in the TERT gene (telomerase reverse transcriptase).

11 Sep 2013

Researchers discover inherited gene mutation linked to childhood leukemia

Researchers have discovered the first inherited gene mutation linked exclusively to acute lymphoblastic leukemia occurring in multiple relatives in individual families. The discovery of the PAX5 gene mutation was led by St. Jude Children's Research Hospital and others. The work appears in the current advance online edition of the scientific journal Nature Genetics.

11 Sep 2013

Biologists identify two pathways via which chromosomes are rearranged

Biologists reported today in Nature that they have identified two pathways through which chromosomes are rearranged in mammalian cells. These types of changes are associated with some cancers and inherited disorders in people.

10 Sep 2013

Scientists develop strain of MERS-CoV that can be used as vaccine against disease

Scientists have developed a strain of the Middle East respiratory syndrome coronavirus (MERS-CoV) that could be used as a vaccine against the disease, according to a study to be published in mBio-, the online open-access journal of the American Society for Microbiology.

10 Sep 2013

Scientists find link between early-onset Parkinson's and 22q11.2 deletion syndrome

Scientists at the Centre for Addiction and Mental Health (CAMH) and University Health Network (UHN) have found a new link between early-onset Parkinson's disease and a piece of DNA missing from chromosome 22. The findings help shed new light on the molecular changes that lead to Parkinson's disease.

10 Sep 2013

Chromosome News and Research

Latest Chromosome News and Research

Length of telomere may help determine prostate cancer patient's prognosis

Genomic instability in CFS is associated with less favorable outcome in patients with CaP

New imaging technique reveals first 3D pictures of chromosome structure

Researchers identify mutation in ITGA10 gene that causes chondrodysplasia in dog breeds

Research finds greater number of 'escaping genes' on X chromosome

Inherited human herpesvirus 6 affects telomere stability and reactivates

Comprehensive changes in lifestyle could reverse ageing

Children with 22q11.2 deletion syndrome may often be misdiagnosed to have autism

Study shows that changes in diet, lifestyle choices may result in longer telomeres

Data can help scientists, physicians match precision drugs to cancer's genetic traits

Findings may help explain why some diabetic women prone to develop kidney failure

Protein plays important role in process of degradation of tumour cells, say researchers

Dartmouth researchers find that protein cyclin A plays important role in cell division process

New research explains how DNA strands repair themselves

Professor to develop DNA sequencing technologies to search for long-range genome interactions

Study: More than 70% of bladder tumors display somatic mutations in TERT gene

Researchers discover inherited gene mutation linked to childhood leukemia

Biologists identify two pathways via which chromosomes are rearranged

Scientists develop strain of MERS-CoV that can be used as vaccine against disease

Scientists find link between early-onset Parkinson's and 22q11.2 deletion syndrome

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Chromosome News and Research

Latest Chromosome News and Research

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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