Chromosome News and Research

Latest Chromosome News and Research

How tuberculosis progresses: genetic factors play a major role

There are almost 1.8 billion people with tuberculosis bacilli in their body, but only about 5% to 15% develop overt infection, usually within 18 months of initial exposure. The reason behind this selective progression has been sought for decades by scientists from a variety of fields.

5 Sep 2019

Large-scale study maps the genetic underpinnings of early TB progression

While the vast majority of the 1.8 billion people infected with the TB bacterium never experience active disease, an estimated 5 to 15 percent do develop full-blown infections--roughly half of them within 18 months of exposure.

4 Sep 2019

Researchers map uncharted area of genome using advanced imaging

Using advanced imaging techniques, researchers at the University of Colorado Anschutz Medical Campus have mapped a previously uncharted region of the human genome that gives rise to a variety of disease, setting the stage to potentially test for the conditions in the future.

4 Sep 2019

Presence of XX sex chromosomes increases risk of heart attacks and coronary artery disease

New research at the University of Kentucky has confirmed that the presence of XX sex chromosomes increases the amount of fat circulating in the blood, which leads to narrowing of the arteries and ultimately a higher risk of heart attacks and coronary artery disease.

3 Sep 2019

Large study quashes idea of “gay gene”

A vast new study including almost half a million people has concluded that no single gene is associated with same-sex behavior.

2 Sep 2019

DNA methylation closely linked to telomere length

Aging is associated with multiple disease conditions. Recently it has been found that many of these illnesses are linked to the length of the telomeres at the ends of every chromosome. Telomere length (TL) is affected by both genetic and epigenetic contributions.

2 Sep 2019

Sick mitochondria pollute the cells, cause telomere damage

Researchers at UPMC Hillman Cancer Center provide the first concrete evidence for the long-held belief that sick mitochondria pollute the cells they're supposed to be supplying with power.

27 Aug 2019

Researchers discover pivotal role for bacterial sex in evolution of mammalian microbiome

In a pioneer study now published in Proceedings of the National Academy of Science - USA, the research team led by Isabel Gordo, from the Instituto Gulbenkian de Ciência, in collaboration with researcher Michael Lässig of Cologne University, used healthy mice to study real-time gut colonization and discovered a pivotal role for bacterial sex in the evolution of the mammalian microbiome.

25 Aug 2019

Study sheds light on emergence and spread of drug-resistant malaria parasites in Africa

In the first continent-wide genomic study of malaria parasites in Africa, scientists have uncovered the genetic features of Plasmodium falciparum parasites that inhabit different regions of the continent, including the genetic factors that confer resistance to anti-malarial drugs.

23 Aug 2019

Scientists identify specific gene that plays key role in several psychiatric conditions

Scientists have identified a specific gene they believe could be a key player in the changes in brain structure seen in several psychiatric conditions, such as schizophrenia and autism.

21 Aug 2019

Simple technique to choose the sex of offspring by separating X and Y sperm

A simple, reversible chemical treatment can segregate X-bearing sperm from Y-bearing sperm, allowing dramatic alteration of the normal 50/50 male/female offspring ratio, according to a new study by Masayuki Shimada and colleagues at Hiroshima University, published on August 13 in the open-access journal PLOS Biology. The study was performed in mice, but the technique is likely to be widely applicable to other mammals as well.

From PLOS ONE 16 Aug 2019

APOE gene variant may be protective and prolong life, finds study

A new study of 38,537 persons of European ancestry suggests that a rare variation of a gene called APOE may be protective and prolong life, in sharp contrast to a more widely studied APOE variant that increases risk of death.

7 Aug 2019

Scientists use AI to recognize patterns in breast cancer

Scientists have used artificial intelligence to recognize patterns in breast cancer - and uncovered five new types of the disease each matched to different personalized treatments.

2 Aug 2019

Discovery of protective protein could open door to better treatment of fast-growing cancer cells

The discovery that an essential protein plays a protective role during cell division, could open the door to better targeted treatment of fast-growing cancer cells.

1 Aug 2019

Common feature that makes cancer cells appear bloated could be their potential weak spot

In a study using yeast cells and data from cancer cell lines, Johns Hopkins University scientists report they have found a potential weak spot among cancer cells that have extra sets of chromosomes, the structures that carry genetic material.

23 Jul 2019

Researchers reveal molecular cause for severe multi-organ disorder

Three unrelated families on three continents (from continental Portugal, the United States and Brazil), all with healthy ancestors, had children with a very rare disease.

18 Jul 2019

BU professor awarded NIH grant to study Down syndrome

Tarik F. Haydar, PhD, professor of anatomy and neurobiology at Boston University School of Medicine, has been awarded a two-year Exploratory/Developmental Research Grant Award (R21) from the National Institutes of Health.

16 Jul 2019

Exciting study shows how centrioles center the process of cell division

All life on earth depends upon the process of mitosis or cell division in which the chromosomal content of a cell is equally divided between two new cells.

12 Jul 2019

Research reveals genetic cause of deadly digestive disease in children

Nearly 10 years ago, a group of Israeli clinical researchers emailed Lawrence Berkeley National Laboratory (Berkeley Lab) geneticist Len Pennacchio to ask for his team's help in solving the mystery of a rare inherited disease that caused extreme, and sometimes fatal, chronic diarrhea in children.

11 Jul 2019

Researchers pinpoint treatment target for rare liver cancer in adolescents, young adults

New findings show how a genetically aberrant, fused protein promotes a rare form of liver cancer in adolescents and young adults. The researchers also saw that a certain mix of drugs could target the fused protein and the enzymes that it recruits.

10 Jul 2019

Chromosome News and Research

Latest Chromosome News and Research

How tuberculosis progresses: genetic factors play a major role

Large-scale study maps the genetic underpinnings of early TB progression

Researchers map uncharted area of genome using advanced imaging

Presence of XX sex chromosomes increases risk of heart attacks and coronary artery disease

Large study quashes idea of “gay gene”

DNA methylation closely linked to telomere length

Sick mitochondria pollute the cells, cause telomere damage

Researchers discover pivotal role for bacterial sex in evolution of mammalian microbiome

Study sheds light on emergence and spread of drug-resistant malaria parasites in Africa

Scientists identify specific gene that plays key role in several psychiatric conditions

Simple technique to choose the sex of offspring by separating X and Y sperm

APOE gene variant may be protective and prolong life, finds study

Scientists use AI to recognize patterns in breast cancer

Discovery of protective protein could open door to better treatment of fast-growing cancer cells

Common feature that makes cancer cells appear bloated could be their potential weak spot

Researchers reveal molecular cause for severe multi-organ disorder

BU professor awarded NIH grant to study Down syndrome

Exciting study shows how centrioles center the process of cell division

Research reveals genetic cause of deadly digestive disease in children

Researchers pinpoint treatment target for rare liver cancer in adolescents, young adults

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Chromosome News and Research

Latest Chromosome News and Research

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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