Cirrhosis News and Research

Latest Cirrhosis News and Research

Sleep-disordered breathing promotes progression of pediatric NAFLD to NASH

Studies have shown that obstructive sleep apnea and low nighttime oxygen, which result in oxidative stress, are associated with the progression of non-alcoholic fatty liver disease (NAFLD) in adults.

5 Aug 2016

New report urges all European countries to adopt universal vaccination for hepatitis

To coincide with World Hepatitis Day, a new report, commissioned by United European Gastroenterology, calls for all European countries to adopt universal vaccination and harmonised screening programmes for hepatitis, as well as improved neonatal screening, to help speed up the eradication of the disease.

1 Aug 2016

New screen-and-treat programme for hepatitis B may thwart deadly complications of disease

Research into Africa's first 'screen-and-treat' programme for hepatitis B suggests the initiative may reduce deadly complications of the virus.

27 Jul 2016

Scientists discover promising approach to combat life-threatening bacterial infections without antibiotics

Patients suffering from liver cirrhosis often die of life-threatening bacterial infections. In these patients the immune cells are unable to eliminate the bacterial infections.

19 Jul 2016

Researchers examine prevalence of CLD among ethnic minority populations in the U.S.

Chronic liver disease (CLD) and cirrhosis are serious liver conditions but little is known about how they affect ethnic minority populations in the United States.

19 Jul 2016

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Mallinckrodt plc, a leading global specialty biopharmaceutical company, today announced new retrospective health economic data on H.P. Acthar® Gel (repository corticotropin injection; RCI), which may be an option for the management of multiple sclerosis (MS) relapses.

6 Jul 2016

FIB-4 index predicts HBV-related HCC

Japanese researchers reveal an association between elevated FIB-4 index 24 weeks after the initiation of nucleos(t)ide analogue therapy and the development of hepatocellular carcinoma in patients with chronic hepatitis B virus infection.

4 Jul 2016

Targeted molecular therapy reduces initial development of NAFLD in mice

Researchers report in the journal Cell Reports a targeted molecular therapy that dramatically reduces the initial development of Non Alcoholic Fatty Liver Disease (NAFLD) in laboratory mouse models of the disease.

1 Jul 2016

Researchers develop in vitro model system for investigating etiology of NAFLD

Researchers from the Institute for Stem Cell Research and Regenerative Medicine at the University Clinic of Düsseldorf have established an in vitro model system for investigating nonalcoholic fatty liver disease (NAFLD).

30 Jun 2016

Epclusa drug receives FDA approval for treating adult patients with chronic HCV

The U.S. Food and Drug Administration approved Epclusa to treat adult patients with chronic hepatitis C virus (HCV) both with and without cirrhosis (advanced liver disease).

28 Jun 2016

Scientists discover link between two genes involved in PD and autoimmune diseases

A study publish in the journal CELL indicates that two genes associated with Parkinson's disease (PD) are key regulators of the immune system, providing direct evidence linking Parkinson's to autoimmune disease.

27 Jun 2016

HCC predictors identified for chronic HBV patients with newly diagnosed cirrhosis

In patients with chronic hepatitis B virus infection who have been newly diagnosed with cirrhosis, the risk of hepatocellular carcinoma development can be ascertained using several clinical and molecular factors, study findings indicate.

23 Jun 2016

Clinical trial finds pioglitazone drug safe and effective for NASH patients

Researchers have found that an existing diabetes drug can be used to halt progression of another disease that is a leading cause of liver transplants.

21 Jun 2016

New studies provide future treatment strategies for stomach ulcers, IBD and alcoholic liver disease

Basic and translational research paves the way for breakthroughs that can ultimately change patient care.

17 Jun 2016

Portal vein hypertension diminishes after hepatitis C recovery

This inflammatory viral infection of the liver causes inflexible scar tissue to form. This in turn impedes blood flow through the organ, with resulting hypertension in the portal vein.

15 Jun 2016

New RNA aptamer can prevent pathogenic protein misfolding

Several diseases occur when mutations cause misfolding of proteins. These include "serpinopathies" which is a group of rare heritable diseases. They are caused by mutations of so-called "serpin" inhibitors of proteolytic enzymes involved in blood coagulation, tissue remodeling, and other important physiological functions.

10 Jun 2016

Novel enzyme immunoassay helps diagnose HCV infection in one simple step

The current standard in diagnosing Hepatitis C virus (HCV) infection requires two sequential steps that make it suboptimal, costly, inconvenient, time consuming, and globally not widely available or affordable.

8 Jun 2016

Scientists use new technique to repair fibrotic liver cells within the organ

Advances in stem cell research have made it possible to convert patients' skin cells into heart cells, kidney cells, liver cells and more in the lab dish, giving researchers hope that one day such cells could replace organ transplantation for patients with organ failure.

3 Jun 2016

Ocaliva drug gets FDA approval for primary biliary cholangitis treatment

On Friday, May 27, the U.S. Food and Drug Administration granted accelerated approval for Ocaliva (obeticholic acid) for the treatment of primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA, or as a single therapy in adults unable to tolerate UDCA.

1 Jun 2016

Portable breath sensor to detect lifestyle diseases? An interview with Osamu Tsuboi, Fujitsu Laboratories

Generally, it is thought that there is a connection between concentrations of ammonia and liver disease, such as fatty liver and cirrhosis, Helicobacter pylori (H. pylori) infection, and kidney failure.

31 May 2016

Cirrhosis News and Research

Latest Cirrhosis News and Research

Sleep-disordered breathing promotes progression of pediatric NAFLD to NASH

New report urges all European countries to adopt universal vaccination for hepatitis

New screen-and-treat programme for hepatitis B may thwart deadly complications of disease

Scientists discover promising approach to combat life-threatening bacterial infections without antibiotics

Researchers examine prevalence of CLD among ethnic minority populations in the U.S.

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

FIB-4 index predicts HBV-related HCC

Targeted molecular therapy reduces initial development of NAFLD in mice

Researchers develop in vitro model system for investigating etiology of NAFLD

Epclusa drug receives FDA approval for treating adult patients with chronic HCV

Scientists discover link between two genes involved in PD and autoimmune diseases

HCC predictors identified for chronic HBV patients with newly diagnosed cirrhosis

Clinical trial finds pioglitazone drug safe and effective for NASH patients

New studies provide future treatment strategies for stomach ulcers, IBD and alcoholic liver disease

Portal vein hypertension diminishes after hepatitis C recovery

New RNA aptamer can prevent pathogenic protein misfolding

Novel enzyme immunoassay helps diagnose HCV infection in one simple step

Scientists use new technique to repair fibrotic liver cells within the organ

Ocaliva drug gets FDA approval for primary biliary cholangitis treatment

Portable breath sensor to detect lifestyle diseases? An interview with Osamu Tsuboi, Fujitsu Laboratories

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Cirrhosis News and Research

Latest Cirrhosis News and Research

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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