Cold, Flu & Cough News and Research

Latest Cold, Flu & Cough News and Research

Identifying SARS-CoV-2 spike protein mutations resistant to antibodies

Using a set of different monoclonal antibodies, researchers determined different mutations in the SARS-CoV-2 spike protein that leads to resistance. Understanding these resistant mutations is important in developing effective therapeutic strategies.

10 Nov 2020

Medical diagnoses of “diseases of despair” increase in Pennsylvania

Medical diagnoses involving alcohol-related disorders, substance-related disorders and suicidal thoughts and behaviors – commonly referred to as diseases of despair – increased in Pennsylvania health insurance claims between the years 2007 and 2018, according to researchers from Penn State Clinical and Translational Science Institute and Highmark Health Enterprise Analytics.

10 Nov 2020

Mask wearing, social distancing considerably reduce incidence of many diseases

Measures to reduce the spread of COVID-19 through non-pharmaceutical interventions (NPIs) such as mask wearing and social distancing are a key tool in combatting the impact of the ongoing coronavirus pandemic.

10 Nov 2020

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

Recently, researchers from The Johns Hopkins University School of Medicine, Baltimore, MD, USA, and Capricor Therapeutics, Inc., Beverly Hills, CA, USA, described a new approach to SARS-CoV-2 vaccine development using exosomes to deliver mRNAs that encode the antigens from multiple structural proteins of the virus.

9 Nov 2020

Heart rate data from wearable devices helps predict SARS-CoV-2 infection

A team of scientists from the Icahn School of Medicine at Mount Sinai in the United States has developed a digital platform to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and related symptoms in healthcare personnel.

9 Nov 2020

Wake Forest Baptist scientists use pre-clinical model to develop a safe, effective flu vaccine for infants

Newborns and young infants are particularly susceptible to the flu and are six times more likely to die from the infection than older children. Currently there is no flu vaccine available for babies less than 6 months old.

9 Nov 2020

ACE2 and TMPRSS2 not the only virus-receptors to mediate SARS-CoV-2 entry

However, a recent study published on the preprint server bioRxiv in November 2020 uncovers the major role played by the N-terminal domain of the SARS-CoV-2 virus in host infection. This could be of great use in measuring the usefulness of antibodies used in convalescent plasma therapy for COVID-19.

9 Nov 2020

Majority of population likely has pre-existing immunity to SARS-CoV-2, claim researchers

A team of researchers has conducted a study suggesting that the majority of the global population is likely to have pre-existing T-cell immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the coronavirus disease 2019 (COVID-19) pandemic.

9 Nov 2020

Cooler temperatures in U.S. may increase COVID-19 cases: New modeling study

How temperature affects the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been a question asked since the pandemic's early days. Just like the flu, which has a substantial seasonal variation, it is believed that SARS-CoV-2 also may be affected by temperature.

9 Nov 2020

Pre-existing antibodies created during COVID-19 may protect children against new pandemic strain

Researchers at the Francis Crick Institute and University College London have found that some antibodies, created by the immune system during infection with common cold coronaviruses, can also target SARS-CoV-2 and may confer a degree of protection against the new viral strain.

9 Nov 2020

Study shows SARS-CoV-2 direct heart muscle cell infection, cell death, loss of contractility

In the study, published on the pre-print journal bioRxiv, the researchers revealed that SARS-CoV-2-infected EHTs manifested the typical characteristics of myocarditis or heart inflammation. These include the stimulation of immune cells, heart cell death, and decreased contractile force generation.

8 Nov 2020

Researchers compare rhesus and cynomolgus macaques for SARS-CoV-2 vaccine trials

A team of researchers at the Biomedical Primate Research Centre based in the Netherlands have aimed to determine the effects of the SARS-CoV-2 pathogen on these monkeys and, subsequently, whether they make good animal models for future research in the area.

8 Nov 2020

SARS-CoV-2 infection risk in day care centers for children and educators is low

Their findings suggest that SARS-CoV-2 infection rarely occurs in daycare centers, and thus, these centers should not be considered as potential reservoirs of the virus. The study is currently available on the medRxiv* preprint server.

8 Nov 2020

Study shows SARS-CoV-2 infection four times more likely through household transmission than community

A group of researchers from across the United States working in collaboration with their Swiss counterparts have conducted an extensive population-based serological survey to understand the transmission dynamics of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) – the novel agent that causes coronavirus disease 2019 (COVID-19).

8 Nov 2020

Decreasing humidity in the winter is likely to lead to more COVID-19 cases

A team of researchers from the Center for Disease Dynamics, Economics & Policy, USA, and Johns Hopkins University, USA, found evidence to support the notion that increased humidity may have contributed to lesser cases in spring earlier this year (2020). However, as the winter season fast approaches, the researchers fear that the decreasing humidity is likely to lead to an increase in COVID-19 cases.

8 Nov 2020

Study shows increasing size of respiratory droplets under cold humid conditions

Considerable evidence has accumulated to suggest that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus may spread through prolonged or brief contact with infected patients - with the infection being spread through respiratory droplets and aerosols. The need to understand how these infectious droplets behave becomes ever more urgent. A recent study published in the preprint server medRxiv* in October 2020 reports the results of such an investigation.

8 Nov 2020

New guideline for juvenile idiopathic arthritis gives emphasis to disease-modifying treatments

The American College of Rheumatology will preview the 2021 Guideline for the Treatment of Juvenile Idiopathic Arthritis at ACR Convergence, the ACR's annual meeting.

6 Nov 2020

Lupus patients receiving prophylactic therapy are at high risk for adverse reactions

New research shows that adults with systemic lupus erythematosus, who receive trimethoprim-sulfamethoxazole (TMP-SMX), a prophylactic therapy to help prevent pneumocystis pneumonia, are at high risk for adverse reactions to the drug, particularly if they are also positive for anti-Smith (anti-Sm) antibodies.

6 Nov 2020

Study: Genetically edited form of herpes simplex virus outperforms leading vaccine candidate

A genetically edited form of a herpes simplex virus -- rewired to keep it from taking refuge in the nervous system and eluding an immune response -- has outperformed a leading vaccine candidate in a new study from the University of Cincinnati, Northwestern University and the University of Nebraska-Lincoln.

6 Nov 2020

COVID-19 hospitalizations and deaths skew towards older males of non-European ancestry

A team of researchers recently investigated the genetic determinants of COVID-19 risk and severity in humans.

6 Nov 2020

Cold, Flu & Cough News and Research

Latest Cold, Flu & Cough News and Research

Identifying SARS-CoV-2 spike protein mutations resistant to antibodies

Medical diagnoses of “diseases of despair” increase in Pennsylvania

Mask wearing, social distancing considerably reduce incidence of many diseases

Exosome-mediated mRNA delivery generates broad immune response to multiple SARS-CoV-2 proteins

Heart rate data from wearable devices helps predict SARS-CoV-2 infection

Wake Forest Baptist scientists use pre-clinical model to develop a safe, effective flu vaccine for infants

ACE2 and TMPRSS2 not the only virus-receptors to mediate SARS-CoV-2 entry

Majority of population likely has pre-existing immunity to SARS-CoV-2, claim researchers

Cooler temperatures in U.S. may increase COVID-19 cases: New modeling study

Pre-existing antibodies created during COVID-19 may protect children against new pandemic strain

Study shows SARS-CoV-2 direct heart muscle cell infection, cell death, loss of contractility

Researchers compare rhesus and cynomolgus macaques for SARS-CoV-2 vaccine trials

SARS-CoV-2 infection risk in day care centers for children and educators is low

Study shows SARS-CoV-2 infection four times more likely through household transmission than community

Decreasing humidity in the winter is likely to lead to more COVID-19 cases

Study shows increasing size of respiratory droplets under cold humid conditions

New guideline for juvenile idiopathic arthritis gives emphasis to disease-modifying treatments

Lupus patients receiving prophylactic therapy are at high risk for adverse reactions

Study: Genetically edited form of herpes simplex virus outperforms leading vaccine candidate

COVID-19 hospitalizations and deaths skew towards older males of non-European ancestry

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Cold, Flu & Cough News and Research

Latest Cold, Flu & Cough News and Research

Pharmaceutical Manufacturing - Industry Focus eBook eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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