Colorectal Cancer News and Research

Latest Colorectal Cancer News and Research

Lilly to acquire ImClone Systems for $6.5 billion

Eli Lilly and Company and ImClone Systems Inc. today announced that the boards of directors of both companies have approved a definitive merger agreement under which Lilly will acquire ImClone through an all cash tender offer of $70.00 per share, or approximately $6.5 billion.

6 Oct 2008

Most young adults under 50 unlikely need colorectal screening

Young adults without a family history of bowel disease are unlikely to develop adenomas, the colorectal polyps most likely to lead to cancer, according to new research directed by scientists at the Johns Hopkins Kimmel Cancer Center. The finding supports current cancer screening guidelines recommending adults in general undergo screening colonoscopies starting at age 50.

2 Oct 2008

Molecule provides new understanding of cause of colon cancer

Scientists investigating a molecule known to play a key role in causing colon cancer have made a series of ground-breaking discoveries that could have major implications for future treatment of the disease, responsible for 655,000 deaths worldwide per year. Their findings are published in the journal Cancer Research.

30 Sep 2008

Surgical treatment provides new option for some colorectal cancer patients

Research out of Wake Forest University School of Medicine suggests that a surgical technique not traditionally used in advanced abdominal cancer may be a viable treatment option for some patients previously thought to be untreatable, offering the real possibility of extending survival for those patients.

30 Sep 2008

Gap in black, white new cancer diagnoses narrowing in Missouri; mortality rate gap falling more slowly, study finds

The gap between blacks and whites in Missouri for newly diagnosed cancers is narrowing in part because of an overall decline in smoking and an increase in cancer screenings, according to a study to be published early next year in the journal Missouri Medicine, the AP/St. Louis Post-Dispatch reports.

29 Sep 2008

New results help predict treatment response in colorectal cancer

Genetic testing can identify a group of patients with advanced colorectal cancer who are likely to survive on average twice as long if treated with the drug cetuximab, late breaking results show.

16 Sep 2008

Inherited one-hit gene mutation provides new opportunity for colon cancer prevention

More than 30 years ago, Alfred Knudson Jr., M.D., Ph.D., revolutionized the field of cancer genetics by showing that a person must lose both their paternal and maternal copies of a particular class of cancer-inhibiting genes, called tumor-suppressor genes, in order to develop cancer.

15 Sep 2008

Many colorectal cancer survivors do not receive recommended follow-up screening

A new analysis reveals that fewer than half of older patients successfully treated for colorectal cancer receive the recommended screening schedule to detect any recurrence of cancer.

10 Sep 2008

Computerized reminder system drove up colon cancer screening rates

A computerized reminder system used in community-based primary care doctors' offices increased colorectal cancer screening rates by an average of 9 percent, according to a new study from the University of Michigan Health System.

7 Sep 2008

FDA grants IND for Davanat to treat breast cancer patient

Pro-Pharmaceuticals, Inc. has announced that the U.S. Food and Drug Administration (FDA) has granted an Investigational New Drug (IND) application for use of Davanat in combination with 5-FU to treat a breast cancer patient at the Brown Cancer Center in Louisville, Kentucky. Davanat also is being administered in Phase II clinical trials for first-line treatment of colorectal and biliary cancer patients.

28 Aug 2008

Obesity raises risks of serious gastrointestinal diseases

The prevalence of obesity and overweight in the United States coupled by the increased risk of gastrointestinal diseases related to obesity raises serious implications for the health of Americans. Several scientific studies in the August issue of The American Journal of Gastroenterology examine the association between obesity and the risk of colorectal cancer and gastroesophageal reflux disease, or GERD.

19 Aug 2008

Discovery of major genetic cause of colorectal cancer

About one-third of colorectal cancers are inherited, but the genetic cause of most of these cancers is unknown. The genes linked to colorectal cancer account for less than 5 percent of all cases.

14 Aug 2008

Cannabinoid cell surface receptor plays a tumor-suppressing role in human colorectal cancer

CB1 is well-established for relieving pain and nausea, elevating mood and stimulating appetite by serving as a docking station for the cannabinoid group of signaling molecules. It now may serve as a new path for cancer prevention or treatment.

3 Aug 2008

Worldwide analysis of cancer survival finds wide variation between countries

Black men and women have substantially lower survival than white men and women in the United States, but US has the highest survival for prostate cancer of all 31 countries included.

16 Jul 2008

"Smothered" genes combine with mutations to yield poor out come in cancer patients

Johns Hopkins Kimmel Cancer Center researchers have identified a set of genes in breast and colon cancers with a deadly combination of traditional mutations and "smothered" gene activity that may result in poor outcomes for patients.

15 Jul 2008

Health partnership expands cancer screening services

The Health Partnership of Monroe County, which evolved from the Women's Health Partnership, has expanded its free cancer screenings for women and men and now offers coverage for the human papilloma virus (HPV) vaccine.

15 Jul 2008

Colorectal cancer screening rates still too low

Although colorectal cancer screening tests are proven to reduce colorectal cancer mortality, only about half of U.S. men and women 50 and older receive the recommended tests, according to a report in the July 2008 issue of Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research.

14 Jul 2008

AMDL granted FDA clearance to market blood test for colorectal cancer

AMDL has announced that the US Food and Drug Administration (FDA) has issued a letter of substantial equivalence to an existing predicate device and granted clearance to market the AMDL-ELISA DR-70(R) (FDP) as a safe and effective blood test for monitoring patients who have been previously diagnosed with colorectal cancer (CRC).

7 Jul 2008

Protein thought to promote cancer instead functions as a tumor suppressor

A protein previously thought to promote colorectal cancer instead suppresses the growth of human cancer cells in culture, researchers at UT Southwestern Medical Center have found.

7 Jul 2008

Senate panel approves $153.1 billion for discretionary spending in labor-HHS-education bill for FY 2009

The Senate Appropriations Labor, HHS, Education and Related Agencies Subcommittee on Tuesday by voice vote approved a $631 billion fiscal year 2009 Labor-HHS-Education appropriations bill, CQ Today reports.

26 Jun 2008