Coronavirus Disease COVID 19 News and Research

Latest Coronavirus Disease COVID 19 News and Research

Pharmacists discover active substances that block SARS-CoV-2 replication

A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. The drug candidates are able to switch off the the key enzyme of the virus, the so-called main protease.

3 Mar 2021

UK public health authorities review early data on the effectiveness of Pfizer and AstraZeneca COVID-19 vaccines

A team of UK scientists has recently evaluated the effectiveness of the Pfizer (BNT162b2) and AstraZeneca (ChAdOx1) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The findings reveal that both vaccines are effective in significantly reducing SARS-CoV-2 infection in older adults and providing long-term protection.

3 Mar 2021

Researchers develop ultrapotent miniproteins that target SARS-CoV-2 receptor-binding domain

Researchers have investigated the effectiveness of a bioengineered miniprotein in protecting against SARS-CoV-2 infection in vivo. The researchers evaluated the miniprotein, LCB1, against SARS-CoV-2-mediated lung disease in human ACE2-expressing transgenic mice.

3 Mar 2021

Obesity may reduce COVID-19 vaccine efficacy, say researchers

A startling indicates that obesity may reduce the immune response to the current COVID-19 vaccines, along with other factors like age and sex. This could have significant implications for vaccination strategies in obese people.

3 Mar 2021

Delayed second dose strategy with mRNA vaccines may reduce COVID-19 mortality, say researchers

An interesting new preprint shows that even if countries are forced to delay the second dose of the current vaccines administered against SARS-CoV-2, to arrest the ongoing COVID-19 pandemic, the cumulative mortality would still fall significantly.

3 Mar 2021

Researchers conduct large meta-analysis of COVID-19’s neurological manifestations

The global spread of the COVID-19 pandemic, caused by SARS-CoV-2, has led to intense interest in the various manifestations of the infection, including its neurological features. A compact summation by researchers across the UK of what is known at present about this facet of the disease is presented in a new paper.

3 Mar 2021

Researchers examine long-term immune responses following COVID-19 across clinically diverse cohort

A new study by researchers at the University of California, San Francisco, discusses the different aspects of long-term immune responses in a wide sample of patients, as well as how they vary in clinical severity and sequelae.

3 Mar 2021

Novel SARS-CoV-2 spike vaccine candidate produces strong neutralizing response in vivo

A new study by researchers at Mahidol University in Bangkok, Thailand, reports a COVID-19 vaccine candidate called HexaPro in producing neutralizing antibodies against the SARS-CoV-2 spike protein in an animal model.

3 Mar 2021

Muscle strength associated with reduced COVID-19 hospitalization in older adults

Exercising more than once a week after 50 years of age is linked to a 60% lower risk of COVID-19 hospitalization. An international team of researchers has found that physical activity involving muscle training can be protective against severe infection.

3 Mar 2021

Severe complication of COVID-19 in children reveals distinct features of virus

A new study of patients with Multisystem Inflammatory Syndrome in Children (MIS-C), a rare but severe complication of COVID-19 in children, reveals distinct immune features of COVID-19 not seen in adults that may clue scientists in to why SARS-CoV-2 infection manifests differently in children compared with adults.

3 Mar 2021

New tool can define how infectious pathogens transport in the air

In the 1995 movie "Outbreak," Dustin Hoffman's character realizes, with appropriately dramatic horror, that an infectious virus is "airborne" because it's found to be spreading through hospital vents.

3 Mar 2021

Aircraft cabins may have lowest levels of aerosol particles, show’s study

If you're looking for an indoor space with a low level of particulate air pollution, a commercial airliner flying at cruising altitude maybe your best option.

3 Mar 2021

COVID-19 disrupts heart muscle contraction, may lead to heart failure

Since early in the pandemic, COVID-19 has been associated with heart problems, including reduced ability to pump blood and abnormal heart rhythms.

3 Mar 2021

How SARS-CoV-2 proteins affect vascular functionality

The study, published on the pre-print server medRxiv, can pinpoint and isolate how each of the SARS-CoV-2 proteins independently affects the endothelial response and directly gauge endothelial functionality.

3 Mar 2021

Study demonstrates long-term neuropsychological consequences following SARS-CoV-2 infection

The study, published in the pre-print server medRxiv, demonstrates the presence of long-lasting neuropsychological sequelae after COVID-19, regardless of the respiratory disease's severity.

2 Mar 2021

SARS-CoV-2 viremia predicts severe COVID-19 disease outcomes

The SARS-CoV-2 plasma viremia has been linked to severe disease and death in COVID-19 cases in small-scale cohort studies. The current study, published on the pre-print server medRxiv, aimed to study the mechanisms behind this relationship.

2 Mar 2021

Early antibody response predicts COVID-19 outcome

To address this gap, researchers from the U.S. evaluated the timing of antibody production against SARS-CoV-2 in hospitalized patients. They used a highly sensitive multiplexed bead-based immunoassay that allows for early detection of anti-SARS-CoV-2 antibodies. The study is published on the preprint server medRxiv.

2 Mar 2021

Quantifying SARS-CoV-2 viral load in hospitalized patients

A new paper, published on the medRxiv preprint server, investigates the role of subgenomic RNA transcripts in SARS-CoV-2 infection. Earlier, scientists believed that subgenomic RNA could be traceable infective markers to monitor infectivity.

2 Mar 2021

A model of vaccine-derived herd immunity against COVID-19 in heterogeneous populations

A recent theoretical paper, currently available on the medRxiv preprint server, unveils a novel vaccination model that shows how a herd immunity threshold (HIT) value which considers heterogeneity is substantially lower in comparison with a HIT value of assuming a homogeneous population – with many implications for further vaccination planning.

2 Mar 2021

Concerning mutation in New York SARS-CoV-2 should be monitored, warn researchers

Researchers at the New York State Department of Health in the United States have said concerning mutations within the B.1.526 lineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has recently become prevalent in New York State warrant further monitoring.

2 Mar 2021

Coronavirus Disease COVID 19 News and Research

Latest Coronavirus Disease COVID 19 News and Research

Pharmacists discover active substances that block SARS-CoV-2 replication

UK public health authorities review early data on the effectiveness of Pfizer and AstraZeneca COVID-19 vaccines

Researchers develop ultrapotent miniproteins that target SARS-CoV-2 receptor-binding domain

Obesity may reduce COVID-19 vaccine efficacy, say researchers

Delayed second dose strategy with mRNA vaccines may reduce COVID-19 mortality, say researchers

Researchers conduct large meta-analysis of COVID-19’s neurological manifestations

Researchers examine long-term immune responses following COVID-19 across clinically diverse cohort

Novel SARS-CoV-2 spike vaccine candidate produces strong neutralizing response in vivo

Muscle strength associated with reduced COVID-19 hospitalization in older adults

Severe complication of COVID-19 in children reveals distinct features of virus

New tool can define how infectious pathogens transport in the air

Aircraft cabins may have lowest levels of aerosol particles, show’s study

COVID-19 disrupts heart muscle contraction, may lead to heart failure

How SARS-CoV-2 proteins affect vascular functionality

Study demonstrates long-term neuropsychological consequences following SARS-CoV-2 infection

SARS-CoV-2 viremia predicts severe COVID-19 disease outcomes

Early antibody response predicts COVID-19 outcome

Quantifying SARS-CoV-2 viral load in hospitalized patients

A model of vaccine-derived herd immunity against COVID-19 in heterogeneous populations

Concerning mutation in New York SARS-CoV-2 should be monitored, warn researchers

Mastering RNA extraction for plant and fungal research – eBook eBook

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

Coronavirus Disease COVID 19 News and Research

Latest Coronavirus Disease COVID 19 News and Research

Mastering RNA extraction for plant and fungal research – eBook eBook

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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