Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

The importance of gene regulation for common human disease

A new study published in Nature Genetics on Sunday 16 September 2007 show that common, complex diseases are more likely to be due to genetic variation in regions that control activity of genes, rather than in the regions that specify the protein code.

17 Sep 2007

Ibuprofen effective in slowing down lung disease in children with cystic fibrosis

The results of a clinical trial, published in late August in the Journal of Pediatrics, indicates that, when used as part of routine therapy, high-dose ibuprofen is safe, and effective in slowing down lung disease in children with cystic fibrosis (CF).

5 Sep 2007

N-acetylcysteine may not be as safe as once thought

Certain preparations taken to enhance athletic performance or stave off disease contain an anti-oxidant that could cause harm.

5 Sep 2007

Discovery of molecular pathway that detects and eliminates defective messenger RNAs from red blood cells

Other such pathways - known as surveillance pathways - operate in a more general way, in many cell types. Knowing how this specific surveillance system works can help researchers better understand hereditary diseases, in this case, thalassemia, a form of anemia, which is the most common genetic disorder worldwide.

3 Aug 2007

Researchers determine structure of protein from pathogen associated with cystic fibrosis

The structure of a novel protein in the bacterium that is the most persistent pathogen in cystic fibrosis (CF) patients has been solved.

16 Jul 2007

First mouse model of lung transplantation

Lung transplants have been performed successfully for more than 20 years in humans but never before in mice – until now.

12 Jul 2007

40 percent of parents willing to have their child's DNA stored in a government biobank

Genetic testing holds great promise for the future. Information generated by genetic testing may provide information that leads to new treatments for common diseases such as heart disease and diabetes.

23 Jun 2007

Acquired DNA key to certain bacterial infection

Researchers announced this week the discovery of a mechanism by which Mycobacterium avium - a bacterium which can result in serious lung infections and is prevalent in emphysema and AIDS patients among others - infects tissue cells or macrophages and thus compromises the body's immunity.

19 Jun 2007

Eurand files NDA for Zentase for the treatment of exocrine pancreatic insufficiency

Eurand has announced that Eurand Pharmaceuticals Ltd. initiated the rolling submission of its new drug application (NDA) with the U.S. Food and Drug Administration (FDA) for Zentase for the treatment of Exocrine Pancreatic Insufficiency (EPI). Zentase (formerly EUR-1008), the company's lead product candidate, has been granted fast-track designation by the FDA.

14 Jun 2007

Study finds large number of new proteins implicated in Huntington's disease

Researchers from four organizations have identified more than 200 new proteins that bind to normal and mutant forms of the protein that causes Huntington's disease (HD).

11 May 2007

Nitric oxide may be the key to why specific drugs for heart failure or asthma lose their effectiveness over time

A naturally occurring molecule in the body appears to control whether certain medications, such as beta adrenergic receptor agonists used in acute heart failure or in inhalers for asthma, lose their effectiveness over time.

4 May 2007

Evidence of very early onset defective bone mineralization in the lumbar spine revealed in children with cystic fibrosis

In a study of children with cystic fibrosis, French researchers found evidence of very early onset defective bone mineralization in the lumbar spine that was not caused by either nutritional status or lung disease.

2 May 2007

Luminex Corporation licenses cystic fibrosis gene patent from John Hopkins

Luminex Corporation has announced that it has acquired a non-exclusive license from The Johns Hopkins University for the rights to use the university's patented cystic fibrosis genetic markers in the company's molecular diagnostic products sold in the United States.

From Luminex 25 Apr 2007

Researchers find way to kill cystic fibrosis superbug, Burkholderia cenocepacia

Researchers from the Schulich School of Medicine & Dentistry at The University of Western Ontario , working with a group from Edinburgh, have discovered a way to kill the cystic fibrosis superbug, Burkholderia cenocepacia.

25 Apr 2007

Muscle restoration in an animal model of Duchenne muscular dystrophy

Using a new type of drug that targets a specific genetic defect, researchers at the University of Pennsylvania School of Medicine, along with colleagues at PTC Therapeutics Inc. and the University of Massachusetts Medical School, have for the first time demonstrated restoration of muscle function in a mouse model of Duchenne's muscular dystrophy (DMD).

24 Apr 2007

New drug offers hope to muscular dystrophy and cystic fibrosis sufferers

Scientists in the United States say an experimental drug may be able to compensate for the genetic error responsible for some cases of Duchenne Muscular Dystrophy (DMD) and cystic fibrosis.

23 Apr 2007

New approach to cystic fibrosis treatment

Researchers at the University of Pennsylvania School of Medicine have discovered that an enzyme produced by lung-infecting bacteria further shuts down a protein that is defective in cystic fibrosis patients.

19 Apr 2007

New automated test for gene mutations causing fragile X syndrome

A new automated test could enable population screening to identify carriers of the gene mutations causing fragile X syndrome (FXS), the most common inherited form of mental retardation, reports a study in the April issue of Genetics in Medicine, published by the American College of Medical Genetics and Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

19 Apr 2007

Rhythmic motion of the lungs clears bacteria

While working to find novel ways to treat the life-threatening disease of cystic fibrosis, researchers at the University of North Carolina have discovered that the rhythmic motion of the lungs during normal breathing is a critical regulator of the clearance of bacteria and other noxious materials.

16 Apr 2007

New device to test for proteins that play important role in human health and disease

A new technology developed at the University of Toronto is revealing biochemical processes responsible for diseases such as cystic fibrosis and could one day pave the way for pharmaceutical applications.

15 Apr 2007

Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

The importance of gene regulation for common human disease

Ibuprofen effective in slowing down lung disease in children with cystic fibrosis

N-acetylcysteine may not be as safe as once thought

Discovery of molecular pathway that detects and eliminates defective messenger RNAs from red blood cells

Researchers determine structure of protein from pathogen associated with cystic fibrosis

First mouse model of lung transplantation

40 percent of parents willing to have their child's DNA stored in a government biobank

Acquired DNA key to certain bacterial infection

Eurand files NDA for Zentase for the treatment of exocrine pancreatic insufficiency

Study finds large number of new proteins implicated in Huntington's disease

Nitric oxide may be the key to why specific drugs for heart failure or asthma lose their effectiveness over time

Evidence of very early onset defective bone mineralization in the lumbar spine revealed in children with cystic fibrosis

Luminex Corporation licenses cystic fibrosis gene patent from John Hopkins

Researchers find way to kill cystic fibrosis superbug, Burkholderia cenocepacia

Muscle restoration in an animal model of Duchenne muscular dystrophy

New drug offers hope to muscular dystrophy and cystic fibrosis sufferers

New approach to cystic fibrosis treatment

New automated test for gene mutations causing fragile X syndrome

Rhythmic motion of the lungs clears bacteria

New device to test for proteins that play important role in human health and disease

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

Cystic Fibrosis News and Research

Latest Cystic Fibrosis News and Research

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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