Cytokines News and Research

Latest Cytokines News and Research

Etanercept found to be ineffective in treating alcoholic hepatitis

A new study from Mayo Clinic finds the use of the drug therapy etanercept ineffective in treating alcoholic hepatitis, an acute inflammation of the liver caused by excessive consumption of alcohol. The results of the study are published in the December issue of Gastroenterology.

1 Dec 2008

Blame your genes: why some people get sicker for longer

People with certain high risk gene combinations are eight times more likely to suffer from a severe and prolonged illness when they have an infection, according to University of New South Wales (UNSW) researchers.

1 Dec 2008

MorphoSys granted U.S. patent on antibodies against GM-CSF to treat inflammatory disorders

MorphoSys AG and the University of Melbourne announced today that the U.S. Patent & Trademark Office (USPTO) has confirmed that it will issue U.S. Patent No. 7,455,836, covering key uses of antibodies against GM-CSF.

25 Nov 2008

Ustekinumab receives positive opinion in Europe for treatment of plaque psoriasis

Janssen-Cilag announced today that ustekinumab, the first in a new class of biologics, has received a positive opinion for the treatment of moderate to severe plaque psoriasis from the European Committee for Medical Products for Human Use (CHMP).

24 Nov 2008

Light drinking has certain health benefits, researchers look at why

While the physiological damage and social havoc created by alcohol abuse and dependency are well-known, it is also true that light-to-moderate drinking has certain health benefits.

20 Nov 2008

Women separated from abusive partners often experience high-disability chronic pain after two years

Despite ample evidence that chronic pain is a serious problem in women with a history of abuse, little is known about the severity and patterns of chronic pain in this population.

18 Nov 2008

A large waistline doubles your risk of premature death

Having a large waistline can almost double your risk of dying prematurely even if your body mass index is within the 'normal' range, according to a new study of over 350,000 people across Europe, published in the New England Journal of Medicine.

12 Nov 2008

Astragalus root plant chemical used to fight HIV

Like other kinds of cells, immune cells lose the ability to divide as they age because a part of their chromosomes known as a telomere becomes progressively shorter with cell division.

11 Nov 2008

New therapeutic target for inflammatory disorders

Researchers at Hospital for Special Surgery have identified a potential new therapeutic target that could be used to treat inflammatory disorders, such as rheumatoid arthritis.

6 Nov 2008

'Natural killer' immune cells reveal factors for reproductive success

Immune cells known as natural killer (NK) cells are linked with pregnancy problems including pre-eclampsia and recurrent miscarriage. Collaborative research between scientists at the Babraham Institute and Centre for Trophoblast Research in Cambridge is illuminating the role that pregnancy-related NK cells play in moderating the biochemical interactions at the boundary between maternal tissues and the developing foetus.

4 Nov 2008

Blood stored for 29 days or more linked to infection

Blood stored for 29 days or more, nearly 2 weeks less than the current standard for blood storage, is associated with a higher infection rate in patients who received transfusions with the blood.

28 Oct 2008

Human rhinovirus found to manipulate genes

Sneezing, runny nose and chills? You might blame the human rhinovirus (HRV), which causes 30 to 50 percent of common colds. But in reality, it's not the virus itself but HRV's ability to manipulate your genes that is the true cause of some of the most annoying cold symptoms.

26 Oct 2008

FDA grants orphan drug status to Reata's pancreatic cancer drug

Reata Pharmaceuticals, Inc. has announced that RTA 402 has been granted orphan drug designation by the U.S. Food and Drug Administration (FDA) for the treatment of pancreatic cancer. RTA 402 is currently being studied in a Phase 1/2 trial in patients with pancreatic cancer, and is also in Phase 2 development for chronic kidney disease.

16 Oct 2008

Discovery of important fat precursor cell

To understand where fat comes from, you have to start with a skinny mouse. By using such a creature, and observing the growth of fat after injections of different kinds of immature cells, Rockefeller University scientists have discovered an important fat precursor cell that may in time explain how changes in the numbers of fat cells might increase and lead to obesity.

5 Oct 2008

Pain is not a symptom of arthritis, pain causes arthritis

Pain is more than a symptom of osteoarthritis, it is an inherent and damaging part of the disease itself, according to a study published today in journal Arthritis and Rheumatism.

29 Sep 2008

Healthy individuals may be at risk for heart disease

In the face of a growing obesity epidemic in the United States, researchers at Wake Forest University Baptist Medical Center have new study results that indicate that how much fat a person has is not as important as where that fat is located when assessing risk for cardiovascular events and metabolic disease.

8 Sep 2008

How fat, less important than where that fat is!

The latest research from the U.S. says how fat a person is may be less important than where that fat is.

8 Sep 2008

Monitoring immune responses in disease

A recent study published in Clinical Immunology, the official journal of the Clinical Immunology Society (CIS), describes a new method enabling the detection of multiple parameters of single human cells.

3 Sep 2008

MorphoSys announces publication of first MOR103 data

MorphoSys AG announced today the publication of a first data package for its most advanced proprietary drug development program MOR103, a fully human HuCAL antibody directed against GM-CSF, in the journal "Molecular Immunology".

2 Sep 2008

Newly uncovered cells may be critical in psoriasis

Psoriasis, one of humanity's oldest known diseases, has also been one of its most misunderstood. But in a new study that could change researchers' perspective of the skin disorder and potentially lead to powerful new drug targets, Rockefeller University scientists have found that the source of psoriasis may be a single population of inflammatory cells that act as instigators by priming the body's immune system for self-attack.

20 Aug 2008