Dementia News and Research

Latest Dementia News and Research

FDA accepts Sunovion’s two LATUDA sNDAs for review

Sunovion Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration (FDA) has accepted for review two supplemental New Drug Applications (sNDAs) for the use of LATUDA as 1) monotherapy and 2) adjunctive therapy to lithium or valproate, both to treat adult patients with depressive episodes associated with bipolar I disorder (bipolar depression).

31 Oct 2012

Intravenous catheter replacement: an interview with Claire Rickard

Peripheral intravenous catheters (“IV drips”) are small plastic tubes inserted into veins, most frequently in the hand or arm.

30 Oct 2012

TTP488 slows cognitive decline in patients with mild to moderate Alzheimer's

A novel, orally administered drug candidate, TTP488, has demonstrated clinical evidence of slowing of cognitive decline over 18 months of therapy in patients with mild to moderate Alzheimer's disease.

30 Oct 2012

Stay active to keep a healthy mind in very old age

Poor physical performance, especially a slow walking speed, is significantly associated with dementia in individuals aged over 90 years, show study results.

29 Oct 2012

Study demonstrates role of IRX4204 in alleviating cognitive decline in animal models of AD

New research presented in October at the 6th Neurodegenerative Conditions Research and Development Conference in San Francisco demonstrates the role of the investigational compound IRX4204 in alleviating cognitive decline in animal models of Alzheimer's disease (AD).

29 Oct 2012

Study describes how Dbr1 gene halts toxic buildup of TDP-43-a protein

Scientists at the Gladstone Institutes and the Stanford University School of Medicine have discovered how modifying a gene halts the toxic buildup of a protein found in nerve cells. These findings point to a potential new tactic for treating a variety of neurodegenerative conditions, including amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease)-a fatal disease for which there is no cure.

29 Oct 2012

Anterior insular cortex associated with human empathy

An international team led by researchers at Mount Sinai School of Medicine in New York has for the first time shown that one area of the brain, called the anterior insular cortex, is the activity center of human empathy, whereas other areas of the brain are not. The study is published in the September 2012 issue of the journal Brain.

25 Oct 2012

Dementia: A National Crisis – a review of the Manchester 2012 conference

It was clear from the title – Dementia: A National Crisis – that the conference would focus on the important challenges facing many people living with dementia in the country today.

24 Oct 2012

U.S. Marshals seize dietary supplements and unapproved drugs from Confidence

At the request of the U.S. Food and Drug Administration, U.S. Marshals recently seized dietary supplements and unapproved drugs from Confidence, Inc., of Port Washington, N.Y.

24 Oct 2012

Study still implicates amyloid beta in causing Alzheimer's dementia

Researchers at Washington University School of Medicine in St. Louis have found a key difference in the brains of people with Alzheimer's disease and those who are cognitively normal but still have brain plaques that characterize this type of dementia.

23 Oct 2012

CSF biomarkers can differentiate patients with Alzheimer's or Parkinson disease

Analysis of specific biomarkers in a cerebrospinal fluid sample can differentiate patients with Alzheimer's disease from those with other types of dementia. The method, which is being studied by researchers at Sahlgrenska Academy, may eventually permit earlier detection of Alzheimer's disease.

23 Oct 2012

Analysis of Cerebrospinal Fluid Biomarkers may help early detection of Alzheimer´S Disease

22 Oct 2012

Acetylsalicylic acid slows decline in brain capacity among the elderly

A daily dose of acetylsalicylic acid equivalent to a fourth of an aspirin may slow the decline in intellectual capacity among elderly individuals with high cardiovascular risk. This is shown in a study by Sahlgrenska Academy, University of Gothenburg, Sweden.

22 Oct 2012

$Researchers find new way to assess risk of osteoporosis, bone fractures in women$

Researchers find new way to assess risk of osteoporosis, bone fractures in women

For women of mixed racial or ethnic backgrounds, a new method for measuring bone health may improve the odds of correctly diagnosing their risk of osteoporosis and bone fractures, according to a UCLA-led study.

20 Oct 2012

True scale of anti-psychotic usage in dementia may be under-estimated

The scale of the challenge to reduce the use of anti-psychotic drugs by people with dementia may be under-estimated, according to researchers from Aston University and the University of East Anglia, working with NHS Kent and Medway. There is a key public health challenge to reduce the prescribing of anti-psychotic drugs to people with dementia as they are thought to be associated with up to 1,800 deaths a year.

19 Oct 2012

Shunting may not ward off poor hydrocephalus cognitive outcomes

Around half of patients with idiopathic normal-pressure hydrocephalus will develop dementia, despite responding to shunting, study findings suggest.

19 Oct 2012

Blood pressure management may slow cognitive decline in PD

Cognitive dysfunction in Parkinson's disease is linked to neurocirculatory abnormalities such as orthostatic and supine hypertension, suggesting early treatment of such abnormalities may slow cognitive decline, say researchers.

17 Oct 2012

New findings on sleep deprivation presented at Neuroscience 2012

New findings presented today report the important role sleep plays, and the brain mechanisms at work as sleep shapes memory, learning, and behavior. The findings were presented at Neuroscience 2012, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

17 Oct 2012

New findings on Alzheimer's disease presented at Neuroscience 2012

Curtailing the imminent rise in Alzheimer's disease (AD) will require early, accurate diagnostic tests and treatments, and researchers are closer to achieving these two goals. New findings in medical imaging, molecular analysis of neurological diseases, and development of treatments using mouse models were presented at Neuroscience 2012, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

15 Oct 2012