Dementia News and Research

Latest Dementia News and Research

Avanir initiates enrollment in AVP-923 Phase II clinical trial for treatment of agitation in AD patients

Avanir Pharmaceuticals, Inc. today announced the enrollment of the first patient in study AVR-131. The study is a Phase II clinical trial investigating the use of AVP-923 for the treatment of agitation in patients with Alzheimer's disease.

5 Sep 2012

FDA approves Novartis’ Exelon Patch to treat mild to moderate AD

The US Food and Drug Administration has approved a higher dose of Exelon Patch (rivastigmine transdermal system) for the treatment of people with mild to moderate Alzheimer's disease.

4 Sep 2012

People with normal blood sugar range may be at increased risk of brain shrinkage

People whose blood sugar is on the high end of the normal range may be at greater risk of brain shrinkage that occurs with aging and diseases such as dementia, according to new research published in the September 4, 2012, print issue of Neurology-, the medical journal of the American Academy of Neurology.

4 Sep 2012

Parkinson disease may share common pathogenic mechanisms with some cancers

A study that used a Utah genealogic database and a statewide cancer registry to examine the relationship between Parkinson disease (PD) and cancer suggests an increased risk of prostate cancer and melanoma in patients with PD and their relatives, according to a report published Online First by Archives of Neurology, a JAMA Network publication.

4 Sep 2012

iBC Quality Solutions helps to change UK care home system

As care homes struggle to stay compliant with regulations, iBC quality solutions company step in to help.

3 Sep 2012

Longer looks: Too many pills for dad; Genetic secrets; A supermarket's dietitian

Job burnout can strike workers in nearly any field, but a new study finds that doctors are at special risk. Nearly 1 in 2 U.S. physicians report at least one symptom of burnout, with doctors at the front line of care particularly vulnerable, the study found -- a significantly higher rate than among the general working population.

1 Sep 2012

Study may spur research into multi-model imaging based biomarker development for AD

Alzheimer's disease (AD) is one of the most common brain disorders, with an estimated 35 million people affected worldwide. In the last decade, research has advanced our understanding of how AD affects the brain. However, diagnosis continues to rely primarily on neuropsychological tests which can only detect the disease after clinical symptoms begin. In a supplement to the Journal of Alzheimer's Disease, investigators report on the development of imaging-based biomarkers that will have an impact on diagnosis before the disease process is set in motion.

31 Aug 2012

Closing in on neurologic biomarker diagnosis

A panel of five cerebrospinal fluid biomarkers may help doctors to accurately diagnose patients with various forms of dementia and parkinsonian disorders, research published in the Archives of Neurology suggests.

30 Aug 2012

Genmab, Janssen partner to develop and commercialize daratumumab for multiple myeloma

Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, announced today that it has executed a global license and development agreement with the Danish company Genmab A/S for the anti-cancer compound, daratumumab.

30 Aug 2012

Elevated CRP is phenotype for familial preserved cognition

The first-degree relatives of very old people with preserved cognition and elevated C-reactive protein have a low risk for developing dementia, research shows.

29 Aug 2012

Researchers discover new genetic disease related to vitamin B12 deficiency

Vitamin B12 is essential to human health. However, some people have inherited conditions that leave them unable to process vitamin B12. As a result they are prone to serious health problems, including developmental delay, psychosis, stroke and dementia. An international research team recently discovered a new genetic disease related to vitamin B12 deficiency by identifying a gene that is vital to the transport of vitamin into the cells of the body.

27 Aug 2012

Lilly’s solanezumab Phase 3 trials on AD do not meet primary endpoints

Eli Lilly and Company today announced that the primary endpoints, both cognitive and functional, were not met in either of the two Phase 3, double-blind, placebo-controlled solanezumab EXPEDITION trials in patients with mild-to-moderate Alzheimer's disease.

24 Aug 2012

Women with Alzheimer's show worse mental deterioration than men

Women with Alzheimer's show worse mental deterioration than men with the disease, even when at the same stage of the condition, according to researchers from the University of Hertfordshire.

24 Aug 2012

Nonoperative management of inflamed gallbladder may be best for elderly

Medical rather than surgical management of acute cholecystitis – or inflamed gallbladder – may be the most appropriate option for elderly patients who may be unsuitable for surgery, report researchers.

23 Aug 2012

Study might help solve the biggest mystery of Parkinson’s

The recent discoveries that α-Synuclein(α-Syn) protein, a central player in Parkinson´s disease (PD) brain destruction, could not only pass from one neuron to another but also exist outside neuronal cells has led to major rethink on the disease.

23 Aug 2012

Simple eye tracking test could hold key to early Alzheimer's diagnosis

A simple eye tracking test could hold the key to earlier Alzheimer's diagnosis, according to new research published today in the Journal of the American Aging Association.

23 Aug 2012

Working memory capacity in patients with Parkinson's can be improved with sleep

People with Parkinson's disease performed markedly better on a test of working memory after a night's sleep, and sleep disorders can interfere with that benefit, researchers have shown.

22 Aug 2012

Parkinson’s disease with dementia falls into two pathologic subgroups

Patients with Parkinson’s disease who also have dementia fall into two main pathologic categories, characterized by neocortical synucleinopathy in isolation and neocortical synucleinopathy with amyloid beta deposition.

20 Aug 2012

People with no dementia symptoms and high protein levels more likely to avoid the disease

People who are free of dementia and have high levels of a protein that indicates the presence of inflammation have relatives who are more likely to avoid the disease as well, according to a new study published in the August 15, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

16 Aug 2012

Book provides up-to-date knowledge about mild cognitive impairment

At least one in ten adults over the age of 65 suffers from Mild Cognitive Impairment, or MCI. This condition, a state between the normal decline in cognition associated with aging and the more precipitous drop caused by a deadly dementia like Alzheimer's disease, has only recently begun to be studied; first identified by the Mayo Clinic in 1999, it was only given an official diagnostic code in late 2006.

16 Aug 2012