Dementia News and Research

Latest Dementia News and Research

Everyday words that describe feelings lost in dementia

Dementia can affect a person’s ability to recognise the meaning of common emotional words such as ‘thrilled’ and ‘annoyed’, according to new research.

25 Jul 2012

Single event of brain trauma can lead to Alzheimer’s

A study, performed in mice and utilizing post-mortem samples of brains from patients with Alzheimer’s disease, found that a single event of a moderate-to-severe traumatic brain injury (TBI) can disrupt proteins that regulate an enzyme associated with Alzheimer’s. The paper, published in The Journal of Neuroscience, identifies the complex mechanisms that result in a rapid and robust post-injury elevation of the enzyme, BACE1, in the brain. These results may lead to the development of a drug treatment that targets this mechanism to slow the progression of Alzheimer’s disease.

25 Jul 2012

Study uncovers pathways by which yoga impacts biological processes

Six months ago, researchers at UCLA published a study that showed using a specific type of yoga to engage in a brief, simple daily meditation reduced the stress levels of people who care for those stricken by Alzheimer's and dementia. Now they know why.

25 Jul 2012

Moderate-to-severe TBI can disrupt proteins that regulate enzyme associated with Alzheimer's

A study, performed in mice and utilizing post-mortem samples of brains from patients with Alzheimer's disease, found that a single event of a moderate-to-severe traumatic brain injury (TBI) can disrupt proteins that regulate an enzyme associated with Alzheimer's.

25 Jul 2012

Topline results from first of four Phase 3 studies of Pfizer's bapineuzumab for Alzheimer's

Pfizer Inc. announced today that the co-primary clinical endpoints, change in cognitive and functional performance compared to placebo, were not met in the Janssen Alzheimer Immunotherapy R&D LLC (Janssen AI)-led Phase 3 trial of intravenous (IV) bapineuzumab in patients with mild-to-moderate Alzheimer's disease who carry the ApoE4 (apolipoprotein E epsilon 4) genotype.

24 Jul 2012

Research roundup: Gastric bypass costs, paying for psychotherapy

Health Expenditures Among High-Risk Patients After Gastric Bypass and Matched Controls -- A few studies have shown that bariatric surgery can help reduce health care spending by obese patients, particularly those with conditions such as diabetes. This latest study looked at 847 patients who received bariatric surgery through the Veterans Affairs medical system. Inpatient and outpatient spending both before and after surgery were compared to 847 obese patients who did not have the operation.

21 Jul 2012

Janssen-Cilag receives positive opinion from EMA CHMP for DACOGEN

Janssen-Cilag International NV announced today that the Committee for Medical Products for Human Use (CHMP) of the European Medicines Agency (EMA) has granted a positive opinion recommending approval of DACOGEN (decitabine) for Injection.

21 Jul 2012

Epithilone D effective in preventing Alzheimer's in animal models

While clinical trial results are being released regarding drugs intended to decrease amyloid production - thought to contribute to decline in Alzheimer's disease - clinical trials of drugs targeting other disease proteins, such as tau, are in their initial phases.

20 Jul 2012

Impaired frontostriatal circuitry linked to cognitive defects in PD

Reduced activation of the frontostriatal circuits may underlie the mild cognitive impairment often seen in patients with early Parkinson’s disease, say researchers.

19 Jul 2012

Dementia patients allowed to live at home thanks to new research program

A Johns Hopkins research program that brought resources and counselors to elderly Baltimore residents with memory disorders such as dementia significantly increased the chance they could continue to live successfully at home, a preference for most of them.

19 Jul 2012

Metabolic syndrome may reduce cerebral blood flow

Metabolic syndrome, a term used to describe a combination of risk factors that often lead to heart disease and type 2 diabetes, seems to be linked to lower blood flow to the brain, according to research by the University of Wisconsin School of Medicine and Public Health.

19 Jul 2012

High ceramide levels may increase a person's risk of AD

Higher levels of a certain fat in the blood called ceramides may increase a person's risk of developing Alzheimer's disease, according to a study published in the July 18, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

19 Jul 2012

Problems walking associated with increased risk of cognitive decline

Problems walking including slow gait and a short stride are associated with an increased risk of cognitive decline, Mayo Clinic researchers have discovered. Their findings are being presented at the Alzheimer's Association International Conference July 14-19 in Vancouver, British Columbia.

19 Jul 2012

Alzheimer’s pathology lies silent for decades

The pathologic process of Alzheimer’s disease begins more than 20 years before clinical symptoms become apparent, say researchers.

18 Jul 2012

GE Healthcare announces final results from [18F]flutemetamol phase 3 study on AD

GE Healthcare today announced the final results from a phase 3 study of the investigational PET amyloid imaging agent, [18F]flutemetamol in terminally ill patients who had agreed to undergo postmortem brain autopsy.

18 Jul 2012

Combination of obesity and vitamin D deficiency may increase risk of diabetes

The combination of obesity and vitamin D deficiency may put people at even greater risk of insulin resistance than either factor alone, according to new research from the Drexel University School of Public Health recently published early online in the journal Diabetes Care.

18 Jul 2012

Study suggests link between binge drinking and risk of dementia in older adults

Researchers from the Peninsula College of Medicine and Dentistry (PCMD), University of Exeter, will present the findings of a new study suggesting a link between binge drinking in older adults and the risk of developing dementia.

18 Jul 2012

New Alzheimer's model derived from skin cells of patients may prove to be more accurate

Researchers at the Alzheimer's Association International Conference 2012 (AAIC 2012) today reported the creation of a new model of Alzheimer's derived from the skin cells of people with the disease that were reprogramed into Alzheimer's brain cells.

17 Jul 2012

People with amnestic MCI more likely to die

Researchers at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center have found that people with a form of mild cognitive impairment (MCI), a risk factor for developing Alzheimer's disease, have twice the risk of dying compared with cognitively normal people. Those with dementia have three times the risk.

17 Jul 2012

Studies provide evidence of connections between MCI and negative health outcomes

Two studies presented today at the Alzheimer's Association International Conference 2012 (AAIC 2012) in Vancouver provide evidence of connections between mild cognitive impairment (MCI) and negative health outcomes – increased isolation and death.

17 Jul 2012