Dendritic Cell News and Research

Latest Dendritic Cell News and Research

University of Chicago researchers awarded NIH grant to develop novel multiple sclerosis treatment

Researchers from the University of Chicago have been awarded a five-year, $1.5 million grant from the National Institutes of Health to develop stimulated dendritic cell-derived exosomes that show remarkable promise as a treatment for multiple sclerosis and other neurological diseases involving loss of myelin, the insulation around nerve fibers.

18 Sep 2013

Genetic deficiency in autism linked to specific molecular and cellular consequences

Brown University researchers have traced a genetic deficiency implicated in autism in humans to specific molecular and cellular consequences that cause clear deficits in mice in how well neurons can grow the intricate branches that allow them to connect to brain circuits. The researchers also show in their study (online Sep. 12, 2013, in Neuron) that they could restore proper neuronal growth by compensating for the errant molecular mechanisms they identified.

13 Sep 2013

UCSF scientists identify new way to manipulate immune system from autoimmune diseases

Scientists from UC San Francisco have identified a new way to manipulate the immune system that may keep it from attacking the body-s own molecules in autoimmune diseases such as type 1 diabetes, rheumatoid arthritis and multiple sclerosis.

10 Sep 2013

New Sponge-Based Therapeutic Cancer Vaccine Begins Human Clinicals

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6 Sep 2013

Research may shed light on what causes people to suffer from life-threatening anxiety disorders

New research at Rutgers University may help shed light on how and why nervous system changes occur and what causes some people to suffer from life-threatening anxiety disorders while others are better able to cope.

20 Aug 2013

Novel neural mechanism may help improve therapies for spinal injuries, neurodegenerative diseases

University of Arizona scientists have discovered an unknown mechanism that establishes polarity in developing nerve cells. Understanding how nerve cells make connections is an important step in developing cures for nerve damage resulting from spinal cord injuries or neurodegenerative diseases such as Alzheimer's.

16 Aug 2013

New treatment technique uses nanoparticles to attack cancer

Researchers at the University of Georgia are developing a new treatment technique that uses nanoparticles to reprogram immune cells so they are able to recognize and attack cancer. The findings were published recently in the early online edition of ACS Nano.

16 Aug 2013

NW Bio receives decision to continue Phase III clinical trial on brain cancer in Germany

Northwest Biotherapeutics (NASDAQ: NWBO)(NW Bio), a biotechnology company developing non-toxic DCVax® personalized immune therapies for solid tumor cancers, announced today that it has received a decision from the German regulatory agency (the Paul Ehrlich Institute, or PEI) under which the Company's Phase III clinical trial will be able to proceed in Germany after the Company makes three modifications, none of which affect the body of the trial or the bases for seeking product approval.

12 Aug 2013

ImmunoCellular initiates ICT-121 phase I trial in patients with recurrent glioblastoma multiforme

ImmunoCellular Therapeutics, Ltd. today announced initiation of a phase I clinical trial of cancer vaccine ICT-121 as a potential treatment for patients with recurrent glioblastoma multiforme.

30 Jul 2013

Statins: A class of cholesterol-lowering drugs may help treat Rett Syndrome

Statins, a class of cholesterol-lowering drugs found in millions of medicine cabinets, may help treat Rett Syndrome, according to a study published today in Nature Genetics. The Rett Syndrome Research Trust (RSRT) funded this work with generous support from the Rett Syndrome Research Trust UK and Rett Syndrome Research & Treatment Foundation.

30 Jul 2013

Researchers discover mechanism that prevents immune system from spinning out of control

A team led by a University of Arizona researcher has discovered a previously unknown mechanism that prevents the immune system from going into overdrive, shedding light not only on how our body controls its response to pathogens but on conditions such as autoimmune diseases, allergies and chronic inflammation as well.

24 Jul 2013

Innovative vaccine could offer hope to patients with advanced ovarian cancer

Loyola University Medical Center is conducting a clinical trial of an innovative vaccine that could offer hope to patients with advanced ovarian cancer.

10 Jul 2013

Cancer immunotherapies promise to be a new tool in fight against cancer

Drugs that direct a cancer patient's immune system to eradicate her or his disease, known as cancer immunotherapies, promise to be a new tool in the fight against cancer. Since the Koch Institute's inception, exploring the close relationship between the immune system and cancer has been one of the Institute's priority research areas.

9 Jul 2013

Research: Systemic dose of dendritic cells prevent rejection in kidney transplantation

A single systemic dose of special immune cells prevented rejection for almost four months in a preclinical animal model of kidney transplantation, according to experts at the University of Pittsburgh School of Medicine.

1 Jul 2013

Researchers test modified dendritic cells in patients with melanoma

In this issue of the Journal of Clinical Investigation, researchers led by Scott Pruitt at Duke University and Merck Research Laboratories report on a human clinical trial in which modified dendritic cells, a component of the immune system, were tested in patients with melanoma.

25 Jun 2013

Research demonstrates need for development of new treatments for regeneration of nerve cells

Researchers at the University of Michigan have evidence that a single gene controls both halves of nerve cells, and their research demonstrates the need to consider that design in the development of new treatments for regeneration of nerve cells.

5 Jun 2013

NewLink Genetics announces results from two clinical studies with indoximod

NewLink Genetics Corporation, an oncology-focused biopharmaceutical company specializing in immunotherapy, today announced results from two clinical studies with indoximod, an orally administered small molecule drug candidate that inhibits the IDO pathway.

3 Jun 2013

DCPrime completes DCP-001 Phase I/IIa study in patients with acute myeloid leukemia

Cancer vaccine company DCPrime today announced the successful completion of its Phase I/IIa study in acute myeloid leukemia.

28 May 2013

NW Bio starts Phase III clinical trial with DCVax-L for brain cancer at King's College Hospital in UK

Northwest Biotherapeutics, a biotechnology company developing DCVax-L personalized immune therapies for solid tumor cancers, today announced that its Phase III clinical trial with DCVax-L for brain cancer has been initiated at King's College Hospital in the UK.

17 May 2013

Researchers reveal how Ebola evades human immune response

Researchers have discovered the mechanism behind one of the Ebola virus' most dangerous attributes: its ability to disarm the adaptive immune system.

3 May 2013

Dendritic Cell News and Research

Latest Dendritic Cell News and Research

University of Chicago researchers awarded NIH grant to develop novel multiple sclerosis treatment

Genetic deficiency in autism linked to specific molecular and cellular consequences

UCSF scientists identify new way to manipulate immune system from autoimmune diseases

New Sponge-Based Therapeutic Cancer Vaccine Begins Human Clinicals

Research may shed light on what causes people to suffer from life-threatening anxiety disorders

Novel neural mechanism may help improve therapies for spinal injuries, neurodegenerative diseases

New treatment technique uses nanoparticles to attack cancer

NW Bio receives decision to continue Phase III clinical trial on brain cancer in Germany

ImmunoCellular initiates ICT-121 phase I trial in patients with recurrent glioblastoma multiforme

Statins: A class of cholesterol-lowering drugs may help treat Rett Syndrome

Researchers discover mechanism that prevents immune system from spinning out of control

Innovative vaccine could offer hope to patients with advanced ovarian cancer

Cancer immunotherapies promise to be a new tool in fight against cancer

Research: Systemic dose of dendritic cells prevent rejection in kidney transplantation

Researchers test modified dendritic cells in patients with melanoma

Research demonstrates need for development of new treatments for regeneration of nerve cells

NewLink Genetics announces results from two clinical studies with indoximod

DCPrime completes DCP-001 Phase I/IIa study in patients with acute myeloid leukemia

NW Bio starts Phase III clinical trial with DCVax-L for brain cancer at King's College Hospital in UK

Researchers reveal how Ebola evades human immune response

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Dendritic Cell News and Research

Latest Dendritic Cell News and Research

Immunology eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

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