Dendritic Cell News and Research

Latest Dendritic Cell News and Research

M. D. Anderson targets asthma and allergic diseases

A new research alliance focuses on a molecular master switch suspected of igniting the inflammatory immune response that drives asthma and other allergic diseases.

20 Sep 2006

Induction of potent antitumor immunity by intratumoral injection of IL-23 transduced dendritic cells

One therapy for treating brain tumors alerts the immune system to the presence of foreign material. A second therapy enhances the first and prolongs the immune system's response.

4 Sep 2006

AIDS vaccine still long way off

Researchers are optimistic about a potential HIV/AIDS vaccine, even though none of the vaccines in development is likely to completely protect people from HIV transmission, participants at the XVI International AIDS Conference in Toronto said at a news conference Tuesday, Reuters reports.

16 Aug 2006

Turning the immune system against cancer

Medicine can now prevent a host of diseases with a mere shot of vaccine. Polio and smallpox are almost non-existent, and mumps and chicken pox are rarely seen nowadays.

4 Aug 2006

Methamphetamine increases production of protein that promotes the spread of the HIV-1 virus in infected drug users

Researchers at the University at Buffalo have presented the first evidence that the addictive drug methamphetamine, or meth, also commonly known as "speed" or "crystal," increases production of a docking protein that promotes the spread of the HIV-1 virus in infected users.

4 Aug 2006

How does the immune system isolate and destroy intruders?

Dendritic cells are the body's "watchdogs". They recognize and then degrade pathogens, isolating characteristic fragments that are recognized by the immune system thus triggering targeted responses.

25 Jul 2006

Natural mechanism protecting tissue allografts from rejection

A molecule expressed during pregnancy seems to turn down the immune system, making it more tolerant of welcome visitors such as a fetus or maybe a transplanted heart, researchers say.

10 Jul 2006

Protein called Elk-1appears to play role in neurodegeneration and schizophrenia

Pprotein called Elk-1 interacts with mitochondria, the energy storehouse of a cell, suggesting that this protein - typically active in the nucleus - could play a role in cell death and mitochondria-related diseases such as neurodegeneration and schizophrenia.

9 Jun 2006

Promising new vaccine delivery approach

The field of vaccine development is getting a boost from new research that has identified a promising vaccine delivery approach, which in animal studies produced long-term immune protection after just one immunization.

31 May 2006

Promising chemo, therapeutic viruses, cutting-edge surgery debut at M. D. Anderson Cancer Center

Brain tumor specialists at The University of Texas M. D. Anderson Cancer Center are poised on the brink of a new era.

10 May 2006

Discovery of new type of cell that generates crucial immune system cells

A new type of cell that generates crucial cells of the immune system has been discovered at The Walter and Eliza Hall Institute.

8 May 2006

Scientists find that growth hormone is produced in the brain

Scientists have found that growth hormone, a substance that is used for body growth, is produced in the brain, according to an article published in the Proceedings of the National Academy of Sciences.

11 Apr 2006

Novel approach to creating a vaccine to treat melanoma

A novel approach to creating a vaccine to treat melanoma has demonstrated promising effectiveness in a new laboratory study led by researchers at The Wistar Institute. About a third of melanoma patients might benefit from such a vaccine.

4 Apr 2006

Researchers reverse juvenile diabetes in animal model

Groundbreaking human clinical trial for type 1 diabetes to start this spring in Pittsburgh - Children's Hospital of Pittsburgh of UPMC researchers reverse juvenile diabetes in animal model; Phase 1 clinical trial approved by FDA.

4 Apr 2006

New way of targeting proteins to exosomes - potential for melanoma, Alzheimer's disease

Researchers at the University of Pennsylvania School of Medicine have discovered how a protein called Pmel17 is sorted by pigment cells in the skin and eye to make a fiber matrix that eventually sequesters melanin, the dark pigment found in skin, hair, and eyes.

28 Mar 2006

Gene therapy treatment for brain tumours and infections

In a study published in the March 15 issue of The Journal of Immunology, researchers at Board of Governors' Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have developed a way to overcome immune privilege in the brain to eradicate potentially deadly brain tumors such as glioblastoma multiforme and other types of brain infections.

27 Mar 2006

First evidence that dendritic cells show unprecedented sensitivity to thimerosal

A team of cell biologists, toxicologists and molecular bioscientists at UC Davis has published a study connecting thimerosal with disruptions in antigen-presenting cells known as dendritic cells obtained from mice.

22 Mar 2006

Interferon-producing killer dendritic cell speeds up immune reactions and fights cancer

A mouse immune cell that plays dual roles as both assassin and messenger, normally the job of two separate cells, has been discovered by an international team of researchers from the United States and France.

7 Mar 2006

A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma

Asthma rates are rapidly increasing, particularly in children. Although asthma is mediated in part by activation of special immune cells called Th2 cells, the precise causes are unclear.

7 Mar 2006

Attaching new cytokine to neural stem cells derived from bone marrow kills brain tumor cells

Attaching a recently discovered cytokine to neural stem cells derived from bone marrow, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute have developed a tool to track and kill malignant brain tumor cells and provide long-term protection against their return.

1 Mar 2006