Dopamine News and Research

Latest Dopamine News and Research

Researchers find direct link between bursting activity of midbrain dopamine neurons and behavior

Researchers are one step closer to understanding the neurobiology that allows people to successfully learn motivated behaviors by associating environmental cues with rewarding outcomes, according to a study published yesterday in the Proceedings of the National Academy of Sciences ' online Early Edition.

6 Apr 2009

Schizophrenia could be caused by faulty signalling in the brain

In the biggest study of its kind, scientists looking in detail at brain samples donated by people with the condition have identified 49 genes that work differently in the brains of schizophrenia patients compared to controls.

2 Apr 2009

Blocking hunger hormone helps fight cocaine addiction

UC Irvine pharmacological researchers have discovered that blocking a hormone related to hunger regulation can limit cocaine cravings.

1 Apr 2009

CSHL neuroscientists propose project to comprehensively map mammalian brain circuits

Thirty-seven scientists from Cold Spring Harbor Laboratory (CSHL) and 20 other major research institutions in the U.S. and Europe have issued a major challenge to the neuroscience community.

1 Apr 2009

Eli Lilly announces inconclusive study results for mGlu2/3 in acute schizophrenia

Eli Lilly and Company has announced inconclusive Phase II clinical trial results from Study HBBI investigating LY2140023 monohydrate, also known as mGlu2/3, for the treatment of patients suffering from acute schizophrenia.

29 Mar 2009

Non-invasive brain scanning technique may trace development of Parkinson's disease

While finding a biomarker for Parkinson's disease that would let physicians screen for or track its progression remains an elusive goal, a team led by a University of Illinois at Chicago neuroscientist has shown that a non-invasive brain scanning technique offers promise.

24 Mar 2009

Experimental Parkinson's therapy may have robust weight-loss effect

A growth factor used in clinical experiments to rescue dying brain cells in Parkinson patients may cause unwanted weight loss if delivered to specific areas of the brain, according to University of Florida researchers in the March online edition of Molecular Therapy.

24 Mar 2009

p11 protein may lead to faster acting antidepressants

Research conducted by Nobel laureate Paul Greengard, Medical Director of The Michael Stern Parkinson's Research Center at The Rockefeller University, Dr. Jennifer L. Warner-Schmidt in New York and colleagues in Sweden, demonstrated in the Journal of Neuroscience that the brain protein called p11 could lead pharmaceutical companies to develop anti-depression drugs that begin working within hours or days rather than the weeks or even months required by current drugs.

23 Mar 2009

FDA approves Symbyax for treatment-resistant depression

The U.S. Food and Drug Administration (FDA) has approved a new indication for Symbyax (olanzapine and fluoxetine HCl capsules), Eli Lilly and Company has announced.

23 Mar 2009

Novel stimulation method sparks hope for Parkinson's disease sufferers

A novel stimulation method, the first potential therapy to target the spinal cord instead of the brain, may offer an effective and less invasive approach for Parkinson's disease treatment, according to pre-clinical data published in the journal Science by researchers at Duke University Medical Center.

20 Mar 2009

Naltrexone can reduce relapse rates among alcohol-dependence patients

Naltrexone, an opioid antagonist approved in 1994 by the U.S. Food and Drug Administration for alcohol-dependence (AD) treatment, can reduce relapse rates among AD patients.

20 Mar 2009

Low to moderate drinking releases 'feel-good' endorphins in the brain, not heavy drinking

Scientists know that alcohol affects the brain, but the specifics remain unclear.

20 Mar 2009

Drug being used to improve cognition affects dopamine, suggesting potential for abuse

Preliminary research in healthy men suggests that the narcolepsy drug modafinil, increasingly being used to enhance cognitive abilities, affects the activity of dopamine in the brain in a way that may create the potential for abuse and dependence, according to a study in the March 18 issue of JAMA.

17 Mar 2009

Parkinson's-linked mutation makes neurons vulnerable to calcium-induced death

A new study reveals the mechanism by which a genetic mutation linked with Parkinson's disease (PD) renders dopamine neurons particularly vulnerable to cell injury and death.

12 Mar 2009

Toxoplasmosis linked to schizophrenia, bipolar disorders

Scientists have discovered how the toxoplasmosis parasite may trigger the development of schizophrenia and other bipolar disorders.

11 Mar 2009

Long-term effects of two common drugs for early Parkinson's similar

A study published online in the Archives of Neurology involving two common drugs used to treat early-stage Parkinson's disease shows that, while the drugs each have advantages and disadvantages, the overall impact tends to even out over a long period of treatment.

10 Mar 2009

Breakthrough method produces Parkinson's disease patient-specific stem cells free of harmful reprogramming genes

Whitehead Institute researchers have developed a novel method to remove potential cancer-causing genes during the reprogramming of skin cells from Parkinson's disease patients into an embryonic-stem-cell-like state.

8 Mar 2009

Breakthrough produces Parkinson's patient-specific stem cells free of harmful reprogramming genes

Deploying a method that removes potentially cancer-causing genes, Whitehead Institute researchers have "reprogrammed" human skin cells from Parkinson's disease patients into an embryonic-stem-cell-like state.

5 Mar 2009

Faulty signalling in the brain may cause schizophrenia

3 Mar 2009

Researchers discover gene variation linked to cocaine addiction and cocaine-induced paranoia

Researchers from Boston University School of Medicine (BUSM) and Yale University School of Medicine and the University of Connecticut School of Medicine, have discovered that variants in the á-endomannosidase (MANEA) gene are associated with cocaine addiction and cocaine-induced paranoia in European American and African American populations.

2 Mar 2009

Dopamine News and Research

Latest Dopamine News and Research

Researchers find direct link between bursting activity of midbrain dopamine neurons and behavior

Schizophrenia could be caused by faulty signalling in the brain

Blocking hunger hormone helps fight cocaine addiction

CSHL neuroscientists propose project to comprehensively map mammalian brain circuits

Eli Lilly announces inconclusive study results for mGlu2/3 in acute schizophrenia

Non-invasive brain scanning technique may trace development of Parkinson's disease

Experimental Parkinson's therapy may have robust weight-loss effect

p11 protein may lead to faster acting antidepressants

FDA approves Symbyax for treatment-resistant depression

Novel stimulation method sparks hope for Parkinson's disease sufferers

Naltrexone can reduce relapse rates among alcohol-dependence patients

Low to moderate drinking releases 'feel-good' endorphins in the brain, not heavy drinking

Drug being used to improve cognition affects dopamine, suggesting potential for abuse

Parkinson's-linked mutation makes neurons vulnerable to calcium-induced death

Toxoplasmosis linked to schizophrenia, bipolar disorders

Long-term effects of two common drugs for early Parkinson's similar

Breakthrough method produces Parkinson's disease patient-specific stem cells free of harmful reprogramming genes

Breakthrough produces Parkinson's patient-specific stem cells free of harmful reprogramming genes

Faulty signalling in the brain may cause schizophrenia

Researchers discover gene variation linked to cocaine addiction and cocaine-induced paranoia

Pharmaceutical Manufacturing - Industry Focus eBook eBook

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

Dopamine News and Research

Latest Dopamine News and Research

Pharmaceutical Manufacturing - Industry Focus eBook eBook

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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