Dopamine News and Research

Latest Dopamine News and Research

Two new studies shed light on tau’s role in Alzheimer’s disease psychosis

Helping to advance Alzheimer’s disease (AD) research, scientists from The Feinstein Institutes for Medical Research have published two studies supporting the connection of tau – a protein in the brain that forms neurofibrillary tangles that are a hallmark of AD and have been linked to chronic traumatic encephalopathy (CTE) from head trauma – with psychosis in AD.

8 Mar 2022

Study identifies two types of brain cells involved in organizing discrete memories

Researchers have identified two types of cells in our brains that are involved in organizing discrete memories based on when they occurred.

7 Mar 2022

Study provides new insights into the communication of bacteria with their host

A newly discovered protein helps bacteria recognize stress hormones in the human body and direct their motion in the host.

7 Mar 2022

Increased levels of dopamine play an important role in transition to REM sleep, mice study suggests

What triggers the mammalian sleep cycle's shift between non-rapid eye movement (NREM) and rapid eye movement (REM) sleep? A new study in mice suggests increased levels of dopamine in a key region of the brain during NREM sleep play an important role in this transition.

3 Mar 2022

Cell stress-related biochemical events may be partly driving Parkinson's disease

Parkinson's disease may be driven in part by cell stress-related biochemical events that disrupt a key cellular cleanup system, leading to the spread of harmful protein aggregates in the brain, according to a new study from scientists at Scripps Research.

23 Feb 2022

Insight into cellular waste disposal could lead to new treatments for neurodegenerative diseases

A 'waste collection' tidies up our cells. If something does not go according to plan, serious diseases such as Alzheimer's or Parkinson's may develop.

20 Feb 2022

Dopamine signaling promotes the development of compulsive reward seeking behavior

Northwestern investigators have discovered that dopamine signaling in the brain's dorsomedial striatum promotes the development of compulsive behaviors in animal models, according to findings published in Current Biology.

7 Feb 2022

Study investigates if prior SARS-CoV-2 infection increases sensitivity to toxin that induces parkinsonism

A recent study explored whether individuals who have recovered from mild to moderate or severe COVID-19 may have an increased risk for developing Parkinson’s disease in the future.

7 Feb 2022

Cerebrovascular impairment persists months after severe acute COVID-19, UK study

Researchers in the United Kingdom have conducted an observational cohort study on hospitalized patients and have found that the degree of severity of acute coronavirus disease 2019 (COVID-19) predicts the occurrence of chronic cerebrovascular impairment. The study further suggests that the levels of cerebrovascular impairment are associated with worse cognitive, mental, and physical well-being.

7 Feb 2022

Music therapy can be an attractive option to manage menopause symptoms and depressed mood

As researchers continue to seek effective treatment options for menopause symptoms as alternatives to proven pharmacologic solutions, a number of innovative therapies have been shown to improve symptoms.

27 Jan 2022

UC researchers to examine how stress hormones affect cell degeneration in Parkinson's patients

Stress can have a negative effect on anyone's health but presents particular challenges for people with Parkinson's disease.

13 Jan 2022

Novel insights about dopamine can help find better drugs for Parkinson's patients

New findings provide a better understanding of how the synthesis of dopamine is regulated in the brain. It may shed new light on the mechanism behind diseases such as Parkinson's.

12 Jan 2022

Study examines the effects of methylphenidate on mental fatigue in multiple sclerosis patients

A team of researchers at Kessler Foundation studied the effects of methylphenidate on mental fatigue in individuals with multiple sclerosis (MS). This is the first study to examine the psychostimulant's effects on 'state' vs 'trait' mental fatigue in MS.

18 Dec 2021

Researchers identify two new AMD drug candidates using a stem-cell-derived model

Using a stem-cell-derived model, researchers have identified two drug candidates that may slow dry age-related macular degeneration (AMD), a leading cause of blindness for which no treatment exists.

15 Dec 2021

Engineering of brain-mimetic injectable hydrogel scaffolds with self-healing properties

A team of scientists bioengineered a physiologically relevant, brain mimetic 3D scaffold for culturing neuronal cells.

15 Dec 2021

Interaction between SARS-CoV-2 N-protein and Parkinson's protein speeds up amyloid formation

Case reports of relatively young COVID-19 patients who developed Parkinson's disease within weeks of contracting the virus have led scientists to wonder if there could be a link between the two conditions.

14 Dec 2021

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

Northwestern investigators have discovered the molecular signature of a subset of dopaminergic neurons with an increased vulnerability to degeneration.

12 Dec 2021

NRG Oncology CC004 trial: Bupropion does not improve sexual desire for female cancer survivors

Despite preliminary supporting evidence that the dopaminergic agent bupropion might improve sexual desire for female cancer survivors, the NRG Oncology CC004 clinical trial determined that bupropion did not improve outcomes when compared to a placebo.

10 Dec 2021

Study uncovers a promising drug candidate to minimize dyskinesia in Parkinson's patients

A new study from Texas Biomedical Research Institute (Texas Biomed) and collaborators has identified a promising drug candidate to minimize uncontrolled, erratic muscle movements, called dyskinesia, associated with Parkinson's disease.

1 Dec 2021

Study provides a new target for therapeutic intervention in Parkinson's disease

In an unexpected discovery, Georgetown University Medical Center researchers have identified what appears to be a significant vascular defect in patients with moderately severe Parkinson's disease.

14 Nov 2021

Dopamine News and Research

Latest Dopamine News and Research

Two new studies shed light on tau’s role in Alzheimer’s disease psychosis

Study identifies two types of brain cells involved in organizing discrete memories

Study provides new insights into the communication of bacteria with their host

Increased levels of dopamine play an important role in transition to REM sleep, mice study suggests

Cell stress-related biochemical events may be partly driving Parkinson's disease

Insight into cellular waste disposal could lead to new treatments for neurodegenerative diseases

Dopamine signaling promotes the development of compulsive reward seeking behavior

Study investigates if prior SARS-CoV-2 infection increases sensitivity to toxin that induces parkinsonism

Cerebrovascular impairment persists months after severe acute COVID-19, UK study

Music therapy can be an attractive option to manage menopause symptoms and depressed mood

UC researchers to examine how stress hormones affect cell degeneration in Parkinson's patients

Novel insights about dopamine can help find better drugs for Parkinson's patients

Study examines the effects of methylphenidate on mental fatigue in multiple sclerosis patients

Researchers identify two new AMD drug candidates using a stem-cell-derived model

Engineering of brain-mimetic injectable hydrogel scaffolds with self-healing properties

Interaction between SARS-CoV-2 N-protein and Parkinson's protein speeds up amyloid formation

Study provides better understanding of the degenerative underpinnings of Parkinson’s disease

NRG Oncology CC004 trial: Bupropion does not improve sexual desire for female cancer survivors

Study uncovers a promising drug candidate to minimize dyskinesia in Parkinson's patients

Study provides a new target for therapeutic intervention in Parkinson's disease

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

Dopamine News and Research

Latest Dopamine News and Research

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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