Dopamine News and Research

Latest Dopamine News and Research

Repeated dopamine release in the brain plays a key role in infant social development

Changing levels of the chemical dopamine, a chemical most associated with motivation, may help explain why stressful experiences during infancy can lead to lasting behavioral issues, a new study in rodents shows.

26 Oct 2021

Study paves the way for development of new therapeutic strategies to treat addiction

Drug addiction is a psychiatric disorder for which no pharmacological treatment with long-term efficacy currently exists. All addictive substances share the property of raising concentrations of the neurotransmitter dopamine within brain regions forming the neural reward circuit.

21 Oct 2021

Brain's motor cortex may play a larger role in Parkinson’s disease, study reveals

The role of neuron and dopamine loss in Parkinson's Disease (PD) has long been recognized by neuroscientists.

19 Oct 2021

Researchers identify brain circuitry involved in emotional aspects of chronic pain

Negative emotional states and physical pain are intimately connected. Numerous people who suffer from chronic, persistent pain also deal with negative emotions and loss of motivation.

18 Oct 2021

Study uncovers neuronal circuitry that may play a key role in mediating pain-induced anhedonia

A new study published today in Nature Neuroscience has uncovered neuronal circuitry in the brain of rodents that may play an important role in mediating pain-induced anhedonia - a decrease in motivation to perform reward-driven behaviors.

18 Oct 2021

Neuroscientists discover specific brain circuit that triggers cocaine relapse in mice

Relapse is a common feature of addiction recovery – two in three patients treated for substance use disorder in the United States relapse within 12 months, according to the Journal of the American Medical Association.

18 Oct 2021

Researchers explore how opioids may have become so widely abused

Researchers may have uncovered new answers on how to create safer opioids. Design a new opioid to bypass the part of brain that feels pleasure, but retain the analgesic properties, which make opioids one of the most effective pain relievers.

15 Oct 2021

Neuroscientists unveil detailed atlas of brain cells

When you clicked to read this story, a band of cells across the top of your brain sent signals down your spine and out to your hand to tell the muscles in your index finger to press down with just the right amount of pressure to activate your mouse or track pad.

6 Oct 2021

Study reveals potential therapeutic target to tackle ADHD and impulsivity

A study published in the journal Pharmacological Research describes the existence of a complex built by dopamine and noradrenergic receptors that could be a therapeutic target of potential interest to tackle the attention deficit hyperactivity disorder (ADHD) and impulsivity.

23 Sep 2021

Discovery points toward a new strategy for treating Parkinson's disease

University of Utah Health scientists have identified a molecule that slows cells' production of alpha-synuclein, a protein that forms toxic aggregates in the brains of people with Parkinson's disease.

23 Sep 2021

Neuroscientists discover how associative memories are formed

Has the scent of freshly baked chocolate chip cookies ever taken you back to afternoons at your grandmother's house? Has an old song ever brought back memories of a first date? The ability to remember relationships between unrelated items (an odor and a location, a song and an event) is known as associative memory.

23 Sep 2021

Increased signaling by sonic hedgehog protein can inhibit LID in Parkinson's patients

Levodopa, or L-dopa, is considered the most effective treatment for Parkinson's disease today. After a few years of treatment, however, almost all patients develop a debilitating side-effect called L-dopa induced dyskinesia, or LID, which causes involuntary movements in the limbs, face, and torso. Deep brain stimulation can alleviate LID, but the procedure is highly invasive and not all patients are eligible.

23 Sep 2021

Revival of the cell and gene therapy field opens new avenues for repairing the Parkinsonian brain

After several decades of pre-clinical development, cell- and gene-based therapies for Parkinson's disease (PD) are now actively being explored.

21 Sep 2021

Discovery points toward a new strategy for treating Parkinson’s disease

University of Utah Health scientists have identified a molecule that slows cells’ production of alpha-synuclein, a protein that forms toxic aggregates in the brains of people with Parkinson’s disease.

21 Sep 2021

Cross-species locomotion features shared by dopamine-deficient worms, mice, and humans

Scientists from the Graduate School of Information Science and Technology at Osaka University used animal location tracking along with artificial intelligence to automatically detect walking behaviors of movement disorders that are shared across species.

18 Sep 2021

Research paves the way for advances in the treatment of many brain disorders

Bristol-led research has identified specific drug targets within the neural circuits that encode memories, paving the way for significant advances in the treatment of a broad spectrum of brain disorders.

16 Sep 2021

Researchers disprove natural antioxidant urate for slowing the progression of Parkinson’s disease

The hypothesis that raising the brain levels of the natural antioxidant urate could slow the progression of Parkinson's disease (PD) has been disproven by researchers at Massachusetts General Hospital.

14 Sep 2021

High levels of stress hormones associated with hypertension and cardiovascular events

Adults with normal blood pressure and high levels of stress hormones were more likely to develop high blood pressure and experience cardiovascular events compared to those who had lower stress hormone levels, according to new research published today in Hypertension, an American Heart Association journal.

13 Sep 2021

Elevated levels of serotonin can curb cocaine addiction in mice

Elevated levels of serotonin can prevent the development of compulsive cocaine seeking and addiction in mice, researchers report.

13 Sep 2021

Neuroscientists reveal brain mechanism related to how serotonin controls cocaine addiction

Contrary to common thinking, cocaine triggers an addiction only in 20% of the consumers. But what happens in their brains when they lose control of their consumption? Thanks to a recent experimental method, neuroscientists at the University of Geneva, Switzerland, have revealed a brain mechanism specific to cocaine, which has the particularity of triggering a massive increase in serotonin in addition to the increase in dopamine common to all drugs.

12 Sep 2021

Dopamine News and Research

Latest Dopamine News and Research

Repeated dopamine release in the brain plays a key role in infant social development

Study paves the way for development of new therapeutic strategies to treat addiction

Brain's motor cortex may play a larger role in Parkinson’s disease, study reveals

Researchers identify brain circuitry involved in emotional aspects of chronic pain

Study uncovers neuronal circuitry that may play a key role in mediating pain-induced anhedonia

Neuroscientists discover specific brain circuit that triggers cocaine relapse in mice

Researchers explore how opioids may have become so widely abused

Neuroscientists unveil detailed atlas of brain cells

Study reveals potential therapeutic target to tackle ADHD and impulsivity

Discovery points toward a new strategy for treating Parkinson's disease

Neuroscientists discover how associative memories are formed

Increased signaling by sonic hedgehog protein can inhibit LID in Parkinson's patients

Revival of the cell and gene therapy field opens new avenues for repairing the Parkinsonian brain

Discovery points toward a new strategy for treating Parkinson’s disease

Cross-species locomotion features shared by dopamine-deficient worms, mice, and humans

Research paves the way for advances in the treatment of many brain disorders

Researchers disprove natural antioxidant urate for slowing the progression of Parkinson’s disease

High levels of stress hormones associated with hypertension and cardiovascular events

Elevated levels of serotonin can curb cocaine addiction in mice

Neuroscientists reveal brain mechanism related to how serotonin controls cocaine addiction

Quality, Patient Safety and Innovation Manager at Elsevier

How Bruker worked with the University of Manchester on mapping the dynamics of complex protein

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Dopamine News and Research

Latest Dopamine News and Research

Quality, Patient Safety and Innovation Manager at Elsevier

How Bruker worked with the University of Manchester on mapping the dynamics of complex protein

Real-time Raman monitoring for pharmaceutical hot melt extrusion

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