Dopamine News and Research

Latest Dopamine News and Research

VCU researchers to study how a gene could influence cognitive decline during chemotherapy

With the help of a $2.1 million grant, Virginia Commonwealth University School of Nursing researchers will study how a gene that regulates estrogen and neurotransmitter levels could be tied to cognitive decline in patients undergoing chemotherapy for breast and endometrial cancers.

27 Sep 2018

Cerevance starts dosing in Phase I clinical trial of CVN424 for treatment of Parkinson's disease

Cerevance, a clinical-stage drug discovery and development company focused on brain diseases, today announced the start of dosing in a Phase I first-in-human clinical trial of CVN424, an oral compound being developed for symptomatic treatment of Parkinson's disease.

25 Sep 2018

Researchers find molecule that halts, reverts neurodegeneration caused by Parkinson's disease

The small SynuClean-D molecule interrupts the formation of the alpha-synuclein amyloid fibers responsible for the onset of Parkinson's disease, and reverts the neurodegeneration caused by the disease.

25 Sep 2018

Environmentally-induced gene activity influences IQ test performance

Is there a link between differences in IQ test performance and the activity of certain genes? Researchers from Charité - Universitätsmedizin Berlin have shown that modifications in the structure of a specific gene have a negative impact on individual test performance.

25 Sep 2018

Ecstasy drug makes octopuses more social

When people take MDMA, the drug popularly known as ecstasy, a rush of serotonin, dopamine, and oxytocin produces feelings of emotional closeness and euphoria, making people more interested than they would normally be in connecting and sharing with other people.

24 Sep 2018

Study offers solid link between visceral organs and brain’s reward, motivation system

A novel gut-to-brain neural circuit establishes the vagus nerve as an essential component of the brain system that regulates reward and motivation, according to research conducted at the Icahn School of Medicine at Mount Sinai and published September 20 in the journal Cell.

21 Sep 2018

Dopamine neurons may involve in conditions ranging from Parkinson's disease to schizophrenia

Dopamine neurons are located in the midbrain, but their tendril-like axons can branch far into the higher cortical areas, influencing how we move and how we feel.

21 Sep 2018

Cannabinoid drugs reduce perceived unpleasantness of painful stimuli and increase tolerance

Researchers in the College of Arts and Sciences have determined that cannabinoid drugs do not appear to reduce the intensity of experimental pain, but, instead, may make pain feel less unpleasant and more tolerable.

19 Sep 2018

Cocaine-addicted rats show long-lasting increases in number of orexin neurons

A study in cocaine-addicted rats reports long-lasting increases in the number of neurons that produce orexin—a chemical messenger important for sleep and appetite—that may be at the root of the addiction.

12 Sep 2018

New dopamine sensors could improve our understanding of Parkinson’s Disease

Researchers have developed a sensor that can measure dopamine in the brain for more than a year. The tech could help us understand Parkinson's and depression.

12 Sep 2018

ADHD patients have increased risk of developing Parkinson's and other similar diseases

While about 11 percent of children (4-17 years old) nationwide have been diagnosed with attention-deficit hyperactivity disorder, the long-term health effects of having ADHD and of common ADHD medications remains understudied.

12 Sep 2018

Tiny sensors can measure dopamine levels in the brain for more than a year

Dopamine, a signaling molecule used throughout the brain, plays a major role in regulating our mood, as well as controlling movement. Many disorders, including Parkinson's disease, depression, and schizophrenia, are linked to dopamine deficiencies.

12 Sep 2018

Mechanically ventilated patients treated with vasopressor may develop ICU-related weakness

At least 25 percent of critically ill patients who receive mechanical ventilation in intensive care units develop muscular weakness severe enough to impair their quality of life.

11 Sep 2018

Immune system that fights infection could join battle against opioid addiction

The same immune system that fights infection and the flu could join the battle against opioid addiction, new research out of the Vanderbilt Center for Addiction Research indicates.

7 Sep 2018

Immune system may join battle against opioid addiction

The same immune system that fights infection and the flu could join the battle against opioid addiction, new research out of the Vanderbilt Center for Addiction Research indicates.

6 Sep 2018

Dopamine receptor study opens door to targeted treatments for neuropsychiatric disorders

New work from researchers at Columbia University Vagelos College of Physicians and Surgeons sheds light on how dopamine receptors signal within cells, opening the door for more targeted--and more tolerable--therapeutics to treat an array of neuropsychiatric disorders.

4 Sep 2018

Sunovion receives Complete Response Letter from FDA for dasotraline NDA

Sunovion Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration issued a Complete Response Letter for the New Drug Application for dasotraline, a novel dual-acting dopamine and norepinephrine reuptake inhibitor, for the treatment of attention-deficit hyperactivity disorder.

3 Sep 2018

Bile acids reduce desire for cocaine, finds study

Bile acids -- gut compounds that aid in the digestion of dietary fats -- reduce the desire for cocaine, according to a new study by researchers at Vanderbilt University Medical Center and the University of Alabama at Birmingham.

31 Aug 2018

Modified Nurr1 protein may pave way for new Parkinson's therapy

Researchers have modified the protein Nurr1 so that it can enter cells from the outside. Nurr1 deficiency may be one of the causes of Parkinson's disease.

31 Aug 2018

Component of cannabis could help in psychosis

Researchers from King’s College London have now found how the chemical cannabidiol or CBD from cannabis can reduce the abnormal brain activity in patients who are at risk of psychosis. The study was published in the latest issue of the journal JAMA Psychiatry.

30 Aug 2018

Dopamine News and Research

Latest Dopamine News and Research

VCU researchers to study how a gene could influence cognitive decline during chemotherapy

Cerevance starts dosing in Phase I clinical trial of CVN424 for treatment of Parkinson's disease

Researchers find molecule that halts, reverts neurodegeneration caused by Parkinson's disease

Environmentally-induced gene activity influences IQ test performance

Ecstasy drug makes octopuses more social

Study offers solid link between visceral organs and brain’s reward, motivation system

Dopamine neurons may involve in conditions ranging from Parkinson's disease to schizophrenia

Cannabinoid drugs reduce perceived unpleasantness of painful stimuli and increase tolerance

Cocaine-addicted rats show long-lasting increases in number of orexin neurons

New dopamine sensors could improve our understanding of Parkinson’s Disease

ADHD patients have increased risk of developing Parkinson's and other similar diseases

Tiny sensors can measure dopamine levels in the brain for more than a year

Mechanically ventilated patients treated with vasopressor may develop ICU-related weakness

Immune system that fights infection could join battle against opioid addiction

Immune system may join battle against opioid addiction

Dopamine receptor study opens door to targeted treatments for neuropsychiatric disorders

Sunovion receives Complete Response Letter from FDA for dasotraline NDA

Bile acids reduce desire for cocaine, finds study

Modified Nurr1 protein may pave way for new Parkinson's therapy

Component of cannabis could help in psychosis

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

Dopamine News and Research

Latest Dopamine News and Research

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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