Dopamine News and Research

Latest Dopamine News and Research

NeuroDerm signs definitive investment agreements for $16 million financing round

NeuroDerm Ltd., a clinical stage pharmaceutical company developing drugs for central nervous system (CNS) diseases, today announced that it has signed definitive investment agreements for a $16 million financing round led by certain of its existing investors with the participation of new investors, including The Elias Group.

21 Aug 2014

Dopamine therapy linked to increased impulse control disorders, daytime sleepiness in early PD patients

New Penn Medicine research shows that neuropsychiatric symptoms such as depression, anxiety and fatigue are more common in newly diagnosed Parkinson's disease (PD) patients compared to the general population.

18 Aug 2014

Dopamine replacement therapy increases impulse control disorders in newly diagnosed PD patients

16 Aug 2014

Discovery of new mechanism could lead to next generation of drugs to treat schizophrenia

Discovery of a new mechanism of drug action could lead to the next generation of drugs to treat schizophrenia.

12 Aug 2014

In vivo dopaminergic imaging strongly correlates with brain pathology

Striatal dopamine transporter binding, assessed using single-photon emission computed tomography, is strongly correlated with substantia nigra cell counts assessed at postmortem, say the authors of a study.

11 Aug 2014

Naltrexone may be effective in diminishing ICD symptoms in PD patients, study finds

Up to 20 percent of Parkinson's disease (PD) patients and their families may confront a common but largely unrecognized challenge: the occurrence of impulse control disorders (ICDs) such as compulsive gambling, sexual behavior, eating, or spending.

31 Jul 2014

Obesity mutation MC4R can significantly contribute to weight gain at early age

People who have the most common genetic mutation linked to obesity respond differently to pictures of appetizing foods than overweight or obese people who do not have the genetic mutation, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

31 Jul 2014

XPro1595 drug can protect vulnerable neurons, reduce motor deficits in Parkinson's model

An experimental anti-inflammatory drug can protect vulnerable neurons and reduce motor deficits in a rat model of Parkinson's disease, researchers at Emory University School of Medicine have shown.

26 Jul 2014

More genetic suspects for schizophrenia brought to light

A meta-analysis from the Schizophrenia Working Group of the Psychiatric Genomics Consortium has revealed a large number of previously unreported genetic loci that may have a role in schizophrenia.

23 Jul 2014

Study explores how changes in dopamine transporter function linked to brain disorders

Recent published research in the Journal of Clinical Investigation demonstrates how changes in dopamine signaling and dopamine transporter function are linked to neurological and psychiatric diseases, including early-onset Parkinsonism and attention deficit hyperactivity disorder (ADHD).

23 Jul 2014

Stimulating specific brain pathway may induce active emergence from anesthesia

Researchers may be one step closer to better understanding how anesthesia works. A study in the August issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists- (ASA-), found stimulating a major dopamine-producing region in the brain, the ventral tegmental area (VTA), caused rats to wake from general anesthesia, suggesting that this region plays a key role in restoring consciousness after general anesthesia.

23 Jul 2014

Findings point to biological mechanisms and pathways that may underlie schizophrenia

As part of a multinational, collaborative effort, researchers from the University of North Carolina School of Medicine and scores of other institutions from all over the world have helped identify over 100 locations in the human genome associated with the risk of developing schizophrenia, in what is the largest genomic study published on any psychiatric disorder to date.

22 Jul 2014

Common genetic variation in gene may modify cardiovascular benefit of aspirin

Aspirin is the gold standard for antiplatelet therapy and a daily low-dose aspirin is widely prescribed for the prevention of cardiovascular disease.

21 Jul 2014

Impaired inhibition of medium spiny neurons linked to depression-like behavior in juvenile WKY rats

Accumulating evidence suggests that the nucleus accumbens, which is involved in mechanisms of reward and addiction, plays a role in the pathogenesis of depression and in the action of antidepressants.

18 Jul 2014

Zhichan decoction promotes dopaminergic neurons following NSC transplantation in PD rats

There is an increasing interest in Parkinson's disease (PD) treatment by increasing dopamine content and reducing dopaminergic metabolites in the brain.

17 Jul 2014

Urge incontinence therapy may relieve stress incontinence

Anticholinergic medication appears to be effective as a treatment for stress and mixed urinary incontinence, results of a small clinical trial indicate.

15 Jul 2014

Imaging biomarker proposed for Parkinson’s disease

Reduced off-medication connectivity in the basal ganglia network separates patients with early Parkinson’s disease from healthy controls with high accuracy, preliminary findings suggest.

15 Jul 2014

Study demonstrates that Parkinson's patients are more creative than their healthy peers

Prof. Rivka Inzelberg of Tel Aviv University's Sackler Faculty of Medicine and the Sagol Neuroscience Center at Sheba Medical Center, Tel Hashomer, documented the exceptional creativity of Parkinson's patients two years ago in a review for Behavioral Neuroscience. Since then, she has conducted the first empirical study to verify a link between Parkinson's disease and artistic inclination.

15 Jul 2014

Sleep problems in PD patients can worsen in later stages of disease

Up to 70% of Parkinson's disease (PD) patients experience sleep problems that negatively impact their quality of life.

11 Jul 2014

Parkinson's disease drug could also help people with phobias or PTSD

A drug used to treat Parkinson's disease could also help people with phobias or post-traumatic stress disorder (PTSD). Scientists of the Translational Neurosciences Research Center at Johannes Gutenberg University Mainz are currently exploring the effects of psychotherapy to extinguish fears in combination with L-dopa.

10 Jul 2014

Dopamine News and Research

Latest Dopamine News and Research

NeuroDerm signs definitive investment agreements for $16 million financing round

Dopamine therapy linked to increased impulse control disorders, daytime sleepiness in early PD patients

Dopamine replacement therapy increases impulse control disorders in newly diagnosed PD patients

Discovery of new mechanism could lead to next generation of drugs to treat schizophrenia

In vivo dopaminergic imaging strongly correlates with brain pathology

Naltrexone may be effective in diminishing ICD symptoms in PD patients, study finds

Obesity mutation MC4R can significantly contribute to weight gain at early age

XPro1595 drug can protect vulnerable neurons, reduce motor deficits in Parkinson's model

More genetic suspects for schizophrenia brought to light

Study explores how changes in dopamine transporter function linked to brain disorders

Stimulating specific brain pathway may induce active emergence from anesthesia

Findings point to biological mechanisms and pathways that may underlie schizophrenia

Common genetic variation in gene may modify cardiovascular benefit of aspirin

Impaired inhibition of medium spiny neurons linked to depression-like behavior in juvenile WKY rats

Zhichan decoction promotes dopaminergic neurons following NSC transplantation in PD rats

Urge incontinence therapy may relieve stress incontinence

Imaging biomarker proposed for Parkinson’s disease

Study demonstrates that Parkinson's patients are more creative than their healthy peers

Sleep problems in PD patients can worsen in later stages of disease

Parkinson's disease drug could also help people with phobias or PTSD

How the Vutara VXL simplifies single-molecule imaging

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Todd Bauman and Chris Povich

Dopamine News and Research

Latest Dopamine News and Research

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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