Dopamine News and Research

Latest Dopamine News and Research

Combination of effective drugs for Parkinson's disease controls symptoms of Rett syndrome in mice

IDIBELL researchers, led by the director of the Program for Epigenetics and Cancer Biology, ICREA researcher and Professor of Genetics at the University of Barcelona, Manel Esteller, have shown that a combination of effective drugs for Parkinson's disease in mice that are used as a model of human Rett syndrome reduces some of the symptoms associated with this disease.

17 Jun 2014

PD MED trial: Levodopa drug better for long-term treatment of newly diagnosed PD

For long-term treatment of newly diagnosed Parkinson’s disease (PD), the old drug levodopa provides better mobility and a higher quality of life than the two main alternatives, dopamine agonists (DA) and monoamine oxidase type B inhibitors (MAOBI), according to the largest-ever trial of PD treatment (PD MED), published in The Lancet.

13 Jun 2014

REM sleep disorder: A sign of impending neurodegenerative disease

How many millions of people suffer from sleep disturbance? One sleep disorder in particular, called REM behavior disorder, could be a sign of impending neurodegenerative disease, including Parkinson's and dementia, say scientists presenting their research at the Society of Nuclear Medicine and Molecular Imaging's 2014 Annual Meeting.

10 Jun 2014

Brain circuit problem may contribute to auditory hallucinations of schizophrenia

St. Jude Children's Research Hospital scientists have identified problems in a connection between brain structures that may predispose individuals to hearing the "voices" that are a common symptom of schizophrenia. The work appears in the June 6 issue of the journal Science.

6 Jun 2014

Dopamine transporter availability predicts ICDs

Reduced striatal dopamine transporter availability is already present in patients with Parkinson’s disease who go on to develop impulse control disorders, a study shows.

5 Jun 2014

Newron Pharmaceuticals submits safinamide NDA to FDA

Newron Pharmaceuticals S.p.A. ("Newron"), a research and development company focused on novel CNS and pain therapies, and its partner Zambon S.p.A., an international pharmaceutical company strongly committed to the CNS therapeutic area with a long experience in respiratory disease therapies, woman care and primary care, announce that the New Drug Application (NDA) for safinamide was submitted today to the US Food and Drug Administration (FDA).

30 May 2014

Stimulation of brain region causes behavioral changes

Artificially stimulating a brain region believed to play a key role in learning, reward and motivation induced monkeys to change which of two images they choose to look at.

30 May 2014

New research program to understand and treat debilitating psychiatric disorders

Scientists and physicians at UC San Francisco (UCSF) are leading a $26 million, multi-institutional research program in which they will employ advanced technology to characterize human brain networks and better understand and treat a range of common, debilitating psychiatric disorders, focusing first on anxiety disorders and major depression.

28 May 2014

Mice with 'mohawk hairstyles' reveal clues to development of autism

"Aha" moments are rare in medical research, scientists say. As rare, they add, as finding mice with Mohawk-like hairstyles.

26 May 2014

New study provides evidence that bacteria in gut may be linked to children with autism

Children with autism spectrum disorders (ASD) have significantly different concentrations of certain bacterial-produced chemicals, called metabolites, in their feces compared to children without ASD.

20 May 2014

Presynaptic dopaminergic lesion predicts drug-induced dyskinesia

Research suggests that the extent of presynaptic dopaminergic denervation before starting therapy may predict which patients with Parkinson’s disease will later develop levodopa-induced dyskinesia.

19 May 2014

Scan may rule out Parkinson’s disease

Patients with clinical symptoms of early Parkinson’s disease but no evidence of dopaminergic deficit on brain imaging are unlikely to have the condition, say the PRECEPT Study investigators.

19 May 2014

New potential treatment for paraplegic patients

People with severe injuries to their spinal cord currently have no prospect of recovery and remain confined to their wheelchairs. Now, all that could change with a new treatment that stimulates the spinal cord using electric impulses.

16 May 2014

Inotropic agents support epoprostenol initiation in severe PAH

Researchers have published a protocol for use of inotropic agents during initiation of epoprostenol therapy in patients with severe pulmonary arterial hypertension.

14 May 2014

Smart drugs have lasting side-effects on young people's brain

Over a million American students misuse prescription drugs or take illegal stimulants to increase their attention span, memory, and capacity to stay awake. Such "smart drugs" become more and more popular due to peer pressure, stricter academic requirements, and the tight job market. But young people who misuse them risk long-term impairments to brain function, warn Kimberly Urban at the University of Delaware and Wen-Jun Gao at Drexel University College of Medicine, USA, in a NIH-funded review published in the open-access journal Frontiers in Systems Neuroscience.

14 May 2014

Research: Stimulation of certain population of neurons within brain can alter learning process

Stimulation of a certain population of neurons within the brain can alter the learning process, according to a team of neuroscientists and neurosurgeons at the University of Pennsylvania.

14 May 2014

Research may offer unique pathway for targeting new therapeutics for addiction treatment

A research team from the Friedman Brain Institute of the Icahn School of Medicine at Mount Sinai has published evidence that shows that subtle changes of inhibitory signaling in the reward pathway can change how animals respond to drugs such as cocaine.

13 May 2014

Neurovance reports positive results from EB-1020 SR phase 2a pilot study in adult ADHD patients

Neurovance, Inc. today announced complete results from its phase 2a pilot study of EB-1020 SR, a non-stimulant, in adult male patients with all subtypes of ADHD (attention deficit hyperactivity disorder).

8 May 2014

Two young neuroscientists win CAN Young Investigator Awards for 2014

The Canadian Association for Neuroscience is proud to announce that Dr. Stephanie Borgland, from the Hotchkiss Brain Institute at University of Calgary, and Dr. Brian Chen, from the Centre for Research in Neuroscience at McGill University, are both winners of CAN Young Investigator Awards for 2014.

8 May 2014

Scientific data confirms therapeutic potential of Anavex's S1R agonist against Parkinson’s disease

Anavex Life Sciences Corp., a clinical stage biopharmaceutical company developing novel drug candidates to treat Alzheimer’s, other diseases of the central nervous system (CNS) and various types of cancer, today announced the findings of a research study published in the current issue of peer-reviewed scientific journal Brain.

30 Apr 2014

Dopamine News and Research

Latest Dopamine News and Research

Combination of effective drugs for Parkinson's disease controls symptoms of Rett syndrome in mice

PD MED trial: Levodopa drug better for long-term treatment of newly diagnosed PD

REM sleep disorder: A sign of impending neurodegenerative disease

Brain circuit problem may contribute to auditory hallucinations of schizophrenia

Dopamine transporter availability predicts ICDs

Newron Pharmaceuticals submits safinamide NDA to FDA

Stimulation of brain region causes behavioral changes

New research program to understand and treat debilitating psychiatric disorders

Mice with 'mohawk hairstyles' reveal clues to development of autism

New study provides evidence that bacteria in gut may be linked to children with autism

Presynaptic dopaminergic lesion predicts drug-induced dyskinesia

Scan may rule out Parkinson’s disease

New potential treatment for paraplegic patients

Inotropic agents support epoprostenol initiation in severe PAH

Smart drugs have lasting side-effects on young people's brain

Research: Stimulation of certain population of neurons within brain can alter learning process

Research may offer unique pathway for targeting new therapeutics for addiction treatment

Neurovance reports positive results from EB-1020 SR phase 2a pilot study in adult ADHD patients

Two young neuroscientists win CAN Young Investigator Awards for 2014

Scientific data confirms therapeutic potential of Anavex's S1R agonist against Parkinson’s disease

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Quality, Patient Safety and Innovation Manager at Elsevier

How Bruker worked with the University of Manchester on mapping the dynamics of complex protein

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Dopamine News and Research

Latest Dopamine News and Research

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Quality, Patient Safety and Innovation Manager at Elsevier

How Bruker worked with the University of Manchester on mapping the dynamics of complex protein

Real-time Raman monitoring for pharmaceutical hot melt extrusion

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