Dopamine News and Research

Latest Dopamine News and Research

New evidence indicates another risk factor for young adults consuming energy drinks

Newfound evidence indicates another risk factor for young adults consuming energy drinks. A research team representing six American universities found that the frequency of energy drink use is associated with increased odds of illicit prescription stimulant medication use.

3 Apr 2014

New therapeutic agent reduces age-related sleep problems in fruit flies

Elderly flies do not sleep well - they frequently wake up during the night and wander around restlessly. The same is true of humans. For researchers at the Max Planck Institute for Biology of Ageing in Cologne, the sleeplessness experienced by the fruit fly Drosophila is therefore a model case for human sleeping behaviour.

2 Apr 2014

Study finds that baclofen drug has potential to prevent cocaine relapse

Relapse is the most painful and expensive feature of drug addiction-even after addicted individuals have been drug-free for months or years, the likelihood of sliding back into the habit remains high. The National Institute on Drug Abuse estimates that 40 to 60 percent of addicted individuals will relapse, and in some studies the rates are as high as 80 percent at six months after treatment.

2 Apr 2014

Northwestern University awarded NIH grant to conduct phase III Parkinson's neuroprotective study

Tanya Simuni, M.D., medical director of Northwestern University's Parkinson's Disease and Movement Disorders Center, was awarded a grant from the National Institutes of Health to conduct a $16 million phase III study of the safety and efficacy of the drug isradipine as a potential neuroprotective agent in Parkinson's disease.

2 Apr 2014

Forest Laboratories, Richter report positive results from cariprazine Phase IIb trial for bipolar depression

Forest Laboratories, Inc. and Gedeon Richter Plc. today announced positive topline results from a Phase IIb trial evaluating the efficacy and safety of the investigational antipsychotic cariprazine in patients with bipolar depression.

31 Mar 2014

Nasal spray holds promise as potential alternative therapeutic approach for depression

A nasal spray that delivers a peptide to treat depression holds promise as a potential alternative therapeutic approach, research from the Centre for Addiction and Mental Health (CAMH) shows.

25 Mar 2014

Dampened reward response tied to schizophrenia risk

The striatal hypoactivation during reward anticipation seen in patients with schizophrenia is also present in their unaffected first-degree relatives, research shows.

17 Mar 2014

Parkinson disease patients with higher CSF experience faster cognitive decline

Counterintuitive Findings Offer New Insights into Parkinson Disease Pathology, According to New Research Published in The American Journal of Pathology

12 Mar 2014

NeuroDerm enrolls patients in second ND0612 Phase II clinical trial for treatment of Parkinson's disease

NeuroDerm, Ltd. announced today that enrollment of patients is ongoing in its second Phase II clinical trial of ND0612, a novel drug formulation for the treatment of Parkinson's disease. ND0612 is a proprietary levodopa/carbidopa liquid formulation under development for continuous subcutaneous administration through a patch pump. It is designed to provide steady levodopa blood levels for the treatment of Parkinson's disease.

11 Mar 2014

FDA-approved anti-psychotic drugs possess tumor-killing activity against glioblastoma

Researchers at the University of California, San Diego School of Medicine have discovered that FDA-approved anti-psychotic drugs possess tumor-killing activity against the most aggressive form of primary brain cancer, glioblastoma. The finding was published in this week's online edition of Oncotarget.

8 Mar 2014

New hydrogel actuator has potential to interact safely with living tissues

Protein from a small, tasty mollusk inspired Michigan Technological University's Bruce P. Lee to invent a new type of hydrogel actuator.

6 Mar 2014

Ultra-high-field MRI provides detailed views of brain area implicated in Parkinson's disease

New research shows that ultra-high-field magnetic resonance imaging (MRI) provides detailed views of a brain area implicated in Parkinson's disease, possibly leading to earlier detection of a condition that affects millions worldwide. The results of this research are published online in the journal Radiology.

5 Mar 2014

Georgia Regents Medical Center explores new treatment for Parkinson's disease-related constipation

Georgia Regents Medical Center is among about a dozen centers nationally exploring the potential of a new drug that may offer relief to people with Parkinson's who have failed standard approaches to treating constipation.

5 Mar 2014

Intra-Cellular Therapies initiates Phase I/II clinical trial to evaluate pharmacokinetics in patients with dementia

Intra-Cellular Therapies, Inc., a biopharmaceutical company focused on the development of therapeutics for central nervous system (CNS) disorders, today announced the initiation of ITI-007-200, a Phase I/II clinical trial designed to evaluate the safety, tolerability and pharmacokinetics of low doses of its lead drug candidate, ITI-007, in healthy geriatric subjects and in patients with dementia, including Alzheimer's disease.

4 Mar 2014

New molecule fluorogenic probe for rapid assessment of individual's risk for Parkinson's disease

A team of researchers from National University of Singapore (NUS) have created the first two-photon, small molecule fluorogenic probe that can serve as a useful tool for the rapid assessment of an individual's potential risk for Parkinson's disease.

3 Mar 2014

Goal: Therapies for hearing loss and communications problems

Research scientist Christine Portfors will study how the brain chemical dopamine influences hearing with support from the National Institutes of Health. The work may ultimately lead to better therapies for people with hearing loss and communication problems.

27 Feb 2014

New research finds direct connection between acupuncture and processes that alleviate sepsis

When acupuncture first became popular in the western hemisphere it had its doubters. It still does. But over time, through detailed observation, scientists have produced real evidence that ancient Chinese practitioners of the medical arts were onto something.

23 Feb 2014

Frequently moving schools during childhood can increase risk of psychotic symptoms in later years

Researchers at Warwick Medical School have shown that frequently moving schools during childhood can increase the risk of psychotic symptoms in later years.

19 Feb 2014

Study examines brain activity of alcohol-dependent women

A new Indiana University study that examines the brain activity of alcohol-dependent women compared to women who were not addicted found stark and surprising differences, leading to intriguing questions about brain network functions of addicted women as they make risky decisions about when and what to drink.

19 Feb 2014

FDA grants accelerated approval to NORTHERA (droxidopa) for patients with symptomatic NOH

Chelsea Therapeutics International, Ltd. today announced that the U.S. Food and Drug Administration granted accelerated approval of NORTHERA (droxidopa) for the treatment of symptomatic neurogenic orthostatic hypotension (NOH). NORTHERA is the first and only therapy approved by the FDA which demonstrates symptomatic benefit in patients with NOH.

18 Feb 2014

Dopamine News and Research

Latest Dopamine News and Research

New evidence indicates another risk factor for young adults consuming energy drinks

New therapeutic agent reduces age-related sleep problems in fruit flies

Study finds that baclofen drug has potential to prevent cocaine relapse

Northwestern University awarded NIH grant to conduct phase III Parkinson's neuroprotective study

Forest Laboratories, Richter report positive results from cariprazine Phase IIb trial for bipolar depression

Nasal spray holds promise as potential alternative therapeutic approach for depression

Dampened reward response tied to schizophrenia risk

Parkinson disease patients with higher CSF experience faster cognitive decline

NeuroDerm enrolls patients in second ND0612 Phase II clinical trial for treatment of Parkinson's disease

FDA-approved anti-psychotic drugs possess tumor-killing activity against glioblastoma

New hydrogel actuator has potential to interact safely with living tissues

Ultra-high-field MRI provides detailed views of brain area implicated in Parkinson's disease

Georgia Regents Medical Center explores new treatment for Parkinson's disease-related constipation

Intra-Cellular Therapies initiates Phase I/II clinical trial to evaluate pharmacokinetics in patients with dementia

New molecule fluorogenic probe for rapid assessment of individual's risk for Parkinson's disease

Goal: Therapies for hearing loss and communications problems

New research finds direct connection between acupuncture and processes that alleviate sepsis

Frequently moving schools during childhood can increase risk of psychotic symptoms in later years

Study examines brain activity of alcohol-dependent women

FDA grants accelerated approval to NORTHERA (droxidopa) for patients with symptomatic NOH

Quality, Patient Safety and Innovation Manager at Elsevier

How Bruker worked with the University of Manchester on mapping the dynamics of complex protein

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Dopamine News and Research

Latest Dopamine News and Research

Quality, Patient Safety and Innovation Manager at Elsevier

How Bruker worked with the University of Manchester on mapping the dynamics of complex protein

Real-time Raman monitoring for pharmaceutical hot melt extrusion

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