Dopamine News and Research

Latest Dopamine News and Research

Biochemical signal in blood is associated with faster-progressing form of Parkinson's

The physical decline experienced by Parkinson's disease patients eventually leads to disability and a lower quality of life. Depending on the individual, the disorder can progress rapidly or slowly.

25 Nov 2013

Study finds resveratrol in colored vegetables, fruits may block effects of methamphetamine

Studies have shown that resveratrol, a natural compound found in colored vegetables, fruits and especially grapes, may minimize the impact of Parkinson's disease, stroke and Alzheimer's disease in those who maintain healthy diets or who regularly take resveratrol supplements.

20 Nov 2013

Two drugs tested in larger trial fail to improve kidney function in patients with acute heart failure

Two drugs tested in a larger trial did not improve kidney function in acute heart failure patients, contrary to results of smaller studies. The results were presented today at the American Heart Association's Scientific Sessions 2013 in Dallas and simultaneously published in the Journal of the American Medical Association. Previous smaller studies showed that low-dose dopamine or low-dose nesiritide could improve kidney function and reduce fluid overload that is often present in hospitalized acute heart failure patients by increasing urine production.

19 Nov 2013

Study identifies patterns of brain activity associated with eating disorders

A growing body of evidence shows the impact of diet on brain function, and identifies patterns of brain activity associated with eating disorders such as binge eating and purging. The findings were presented at Neuroscience 2013, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

14 Nov 2013

New view can give scientists better understanding of how antidepressants work in human brain

Research from Oregon Health & Science University's Vollum Institute, published in the current issue of Nature, is giving scientists a never-before-seen view of how nerve cells communicate with each other.

13 Nov 2013

Simple dot test could help doctors gauge extent of dopamine loss in Parkinson's patients

A pilot study by a multi-disciplinary team of investigators at Georgetown University suggests that a simple dot test could help doctors gauge the extent of dopamine loss in individuals with Parkinson's disease. Their study is being presented at Neuroscience 2013, the annual meeting of the Society for Neuroscience.

11 Nov 2013

Lifestyle changes in diet and exercise show promise for learning, depression in teens

New studies released today underscore the potential impact of healthy lifestyle choices in treating depression, the effects of aging, and learning. The research focused on the effects of mind/body awareness, exercise, and diet, and was presented at Neuroscience 2013, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

10 Nov 2013

Reviva announces successful completion of End-of-Phase 2 meeting for RP5063 drug

Reviva Pharmaceuticals, Inc., a privately held pharmaceutical company focused on the discovery and development of new, safer and highly effective therapies for chronic indications, announced today the successful completion of an End-of-Phase 2 meeting with the Food and Drug Administration for its lead, new investigational antipsychotic drug, RP5063.

5 Nov 2013

Rat study shows compulsive gambling behaviours can be reduced in humans

With the help of a rat casino, University of British Columbia brain researchers have successfully reduced behaviours in rats that are commonly associated with compulsive gambling in humans.

31 Oct 2013

Acacia Pharma begins APD403 Phase II study to prevent chemotherapy-induced nausea & vomiting

Acacia Pharma, a pharmaceutical company specialising in the development of drugs for supportive care, announces the initiation of a Phase II study of APD403 in the prevention of chemotherapy-induced nausea & vomiting (CINV).

30 Oct 2013

Serotonin 2C receptors induce fast-acting antidepressant effects in mice

More than 1 in 10 Americans take antidepressants, but these medications can take weeks-and for some patients, months-before they begin to alleviate symptoms. Now, scientists from the University of Chicago have discovered that selectively blocking a serotonin receptor subtype induces fast-acting antidepressant effects in mice, indicating a potential new class of therapeutics for depression. The work was published Oct. 29 in Molecular Psychiatry.

29 Oct 2013

Researchers describe why current medications only moderately reduce Fragile X symptoms

When you experience something, neurons in the brain send chemical signals called neurotransmitters across synapses to receptors on other neurons. How well that process unfolds determines how you comprehend the experience and what behaviors might follow. In people with Fragile X syndrome, a third of whom are eventually diagnosed with Autism Spectrum Disorder, that process is severely hindered, leading to intellectual impairments and abnormal behaviors.

24 Oct 2013

Modeling, identifying predictors of Parkinson's disease with stem cells

The New York Stem Cell Foundation Research Institute has entered into a partnership with the Parkinson's Progression Markers Initiative to build resources for studying Parkinson's disease to accelerate new treatments. Sponsored by The Michael J. Fox Foundation for Parkinson's Research, PPMI is a landmark effort to identify and validate biomarkers of Parkinson's disease.

15 Oct 2013

Study: Depression in Parkinson's patients may reflect impaired striatal dopamine function

According to the Parkinson's Disease Foundation, up to 60% of individuals with Parkinson's disease (PD) exhibit mild to moderate depression, which is often underdiagnosed.

11 Oct 2013

Depression in Parkinson's disease people associated with reduced dopamine synthesis capacity

According to the Parkinson's Disease Foundation, up to 60% of individuals with Parkinson's disease exhibit mild to moderate depression, which is often underdiagnosed. It is unclear whether depression results from having a debilitating disease or reflects a parallel abnormal change in the brain caused by PD pathophysiology.

11 Oct 2013

Cholinergic degeneration marks gait speed in Parkinson’s patients

Gait speed is preserved in patients with Parkinson’s disease who have isolated dopaminergic denervation, but reduced in those with comorbid cholinergic denervation, research shows.

10 Oct 2013

Diverse Neurological Disorders Appear To Share Tangled Metabolic Roots

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10 Oct 2013

Drugs often fail to bring acromegaly under control in routine clinical practice

Over a quarter of UK patients treated for growth hormone-producing tumours do not achieve 'safe' growth hormone levels, according to a 30 year UK multi-centre study of clinical management of the rare disease acromegaly. The findings by the Society for Endocrinology UK Acromegaly Register, published in the November issue of Clinical Endocrinology, show that drugs to control acromegaly often fail to bring the disease completely under control in routine clinical practice.

10 Oct 2013

Gene mutation offers clues to development of diverse neurological disorders

A research team, headed by Theodore Friedmann, MD, professor of pediatrics at the University of California, San Diego School of Medicine, says a gene mutation that causes a rare but devastating neurological disorder known as Lesch-Nyhan syndrome appears to offer clues to the developmental and neuronal defects found in other, diverse neurological disorders like Alzheimer's, Parkinson's and Huntington's diseases.

10 Oct 2013

TSRI scientists identify set of compounds to treat multiple sclerosis in new way

Scientists at The Scripps Research Institute (TSRI) have identified a set of compounds that may be used to treat multiple sclerosis (MS) in a new way. Unlike existing MS therapies that suppress the immune system, the compounds boost a population of progenitor cells that can in turn repair MS-damaged nerve fibers.

10 Oct 2013

Dopamine News and Research

Latest Dopamine News and Research

Biochemical signal in blood is associated with faster-progressing form of Parkinson's

Study finds resveratrol in colored vegetables, fruits may block effects of methamphetamine

Two drugs tested in larger trial fail to improve kidney function in patients with acute heart failure

Study identifies patterns of brain activity associated with eating disorders

New view can give scientists better understanding of how antidepressants work in human brain

Simple dot test could help doctors gauge extent of dopamine loss in Parkinson's patients

Lifestyle changes in diet and exercise show promise for learning, depression in teens

Reviva announces successful completion of End-of-Phase 2 meeting for RP5063 drug

Rat study shows compulsive gambling behaviours can be reduced in humans

Acacia Pharma begins APD403 Phase II study to prevent chemotherapy-induced nausea & vomiting

Serotonin 2C receptors induce fast-acting antidepressant effects in mice

Researchers describe why current medications only moderately reduce Fragile X symptoms

Modeling, identifying predictors of Parkinson's disease with stem cells

Study: Depression in Parkinson's patients may reflect impaired striatal dopamine function

Depression in Parkinson's disease people associated with reduced dopamine synthesis capacity

Cholinergic degeneration marks gait speed in Parkinson’s patients

Diverse Neurological Disorders Appear To Share Tangled Metabolic Roots

Drugs often fail to bring acromegaly under control in routine clinical practice

Gene mutation offers clues to development of diverse neurological disorders

TSRI scientists identify set of compounds to treat multiple sclerosis in new way

Pharmaceutical Manufacturing - Industry Focus eBook eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Dopamine News and Research

Latest Dopamine News and Research

Pharmaceutical Manufacturing - Industry Focus eBook eBook

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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