Dopamine News and Research

Latest Dopamine News and Research

Continuing spinal cord stimulation improves symptoms of Parkinson's disease

Researchers at Duke Medicine have shown that continuing spinal cord stimulation appears to produce improvements in symptoms of Parkinson's disease, and may protect critical neurons from injury or deterioration.

24 Jan 2014

Gene therapy edges closer for Parkinson’s disease

Lentiviral vector-based gene therapy is well tolerated and may improve motor function in patients with Parkinson’s disease, shows an open-label study published in The Lancet.

20 Jan 2014

Deep-brain stimulation boosts PD patients’ driving performance

Deep-brain stimulation reduces errors among patients with Parkinson’s disease undergoing a driving simulator test, a study shows.

14 Jan 2014

Neurovance announces interim results from phase 2a pilot study of EB-1020 SR in patients with all subtypes of ADHD

Neurovance Inc. today announced interim results from its phase 2a pilot study of EB-1020 SR in adult patients with all subtypes of ADHD. With the four week trial fully enrolled and dosing completed in the majority of patients, the results indicate a statistically significant improvement in ADHD symptoms.

10 Jan 2014

Antipsychotic medication can actively combat cells of difficult-to-treat form of ALL

In a prime example of finding new uses for older drugs, studies in zebrafish show that a 50-year-old antipsychotic medication called perphenazine can actively combat the cells of a difficult-to-treat form of acute lymphoblastic leukemia. The drug works by turning on a cancer-suppressing enzyme called PP2A and causing malignant tumor cells to self-destruct.

9 Jan 2014

Study raises hopes for new drugs to treat brain disorders associated with neurotransmitter imbalance

Although drugs have been developed that inhibit the imbalance of neurotransmitters in the brain - a condition which causes many brain disorders and nervous system diseases - the exact understanding of the mechanism by which these drugs work has not yet been fully understood.

8 Jan 2014

New ways to treat substance abuse, neurological diseases and mental illnesses

Researchers at the University at Buffalo have found a way to change alcohol drinking behavior in rodents, using the emerging technique of optogenetics, which uses light to stimulate neurons.

7 Jan 2014

Molecule produced by brain acts as natural defence mechanism against cannabis

Two INSERM research teams led by Pier Vincenzo Piazza and Giovanni Marsicano (INSERM Unit 862 "Neurocentre Magendie" in Bordeaux) recently discovered that pregnenolone, a molecule produced by the brain, acts as a natural defence mechanism against the harmful effects of cannabis in animals.

3 Jan 2014

Parkinson's disease patients may find difficulties in recognizing emotions

Patients affected by Parkinson's disease may experience, in addition to the more obvious motor symptoms (such as tremors and stiffness), difficulties recognizing emotions in the facial expressions and speech prosody (intonation) of other people. A number of investigations have shown that even deep brain stimulation, a treatment that has become widely used in recent years, may cause similar disorders.

20 Dec 2013

Study investigates about emotions that affects patients with Parkinson's disease

Is it the disease itself or the treatment that impairs the perception of emotions? A study conducted with the collaboration of the International School for Advanced Studies (SISSA) of Trieste investigates the origins of the difficulty recognizing certain emotions that affects patients with Parkinson's disease.

19 Dec 2013

New RUB project to unravel role of enzyme Parkin in promoting neuronal survival

Cell biologists at the Ruhr-Universit-t Bochum have launched a new project to unravel the role of the enzyme Parkin in promoting neuronal survival. The team of Prof Dr Konstanze F. Winklhofer from the Institute of Physiological Chemistry, Department of Molecular Cell Biology, is looking for new therapeutic options to treat Parkinson's disease. The Michael J. Fox Foundation finances this research project with 125,000 US Dollars.

18 Dec 2013

DCC gene involved in adolescent brain development may play a role in mental health vulnerability

As many parents of mentally ill adults will confirm anecdotally, the first symptoms of "something not quite right" with their children begin to appear during the teen years. It is known that during this teenaged phase of brain development, adolescents are particularly vulnerable to psychiatric disorders, including schizophrenia, depression and drug addiction.

17 Dec 2013

Researchers gain better understanding of neurochemical basis of addiction with optogenetics

Wake Forest Baptist Medical Center researchers are gaining a better understanding of the neurochemical basis of addiction with a new technology called optogenetics.

16 Dec 2013

Otsuka, Lundbeck to develop investigational vaccine candidate for Alzheimer's disease

H. Lundbeck A/S (Lundbeck) and Otsuka Pharmaceutical Co., Ltd. (Otsuka) today announced that they will further expand their collaboration to include the development of Lu AF20513, an investigational vaccine candidate for Alzheimer's disease.

11 Dec 2013

Research highlights value of fathers in both neurobiology and behavior of offspring

Even with today's technology, it still takes both a male and a female to make a baby. But is it important for both parents to raise that child? Many studies have outlined the value of a mother, but few have clearly defined the importance of a father, until now.

5 Dec 2013

Researchers discover how PC7 protein affects certain types of cognitive performance

A team of Montr-al researchers at the IRCM led by Dr. Nabil G. Seidah, in collaboration with Dr. William C. Wetsel's team at Duke University in the United States, discovered that the protein PC7 plays a critical role in the brain by affecting certain types of cognitive performance such as anxiety, learning and emotional memory. Their results, recently published in the scientific journals Proceedings of the National Academy of Sciences (PNAS) and Nature, could have a significant impact on regulating behaviour related to anxiety disorders and trauma.

4 Dec 2013

Forest Laboratories to acquire exclusive rights in the U.S. for Saphris sublingual tablets

Forest Laboratories Holdings Limited, a wholly owned subsidiary of Forest Laboratories, Inc. today announced that the company is acquiring exclusive rights in the United States for Saphris (asenapine) sublingual tablets, a treatment for adult patients with schizophrenia or acute bipolar mania, from Merck Sharp & Dohme B.V., a wholly owned subsidiary of Merck & Co., Inc.

3 Dec 2013

MRI provides noninvasive way to measure iron levels in the brains of ADHD people

Magnetic resonance imaging provides a noninvasive way to measure iron levels in the brains of people with attention deficit hyperactivity disorder, according to a study being presented today at the annual meeting of the Radiological Society of North America. Researchers said the method could help physicians and parents make better informed decisions about medication.

2 Dec 2013

Mutation in alpha-synuclein gene causes increased vulnerability to pesticides, leading to Parkinson's

A team of researchers has brought new clarity to the picture of how gene-environmental interactions can kill nerve cells that make dopamine. Dopamine is the neurotransmitter that sends messages to the part of the brain that controls movement and coordination.

27 Nov 2013

Study links genetic predisposition to childhood obesity

Research has suggested that a particular gene in the brain's reward system contributes to overeating and obesity in adults. This same variant has now been linked to childhood obesity and tasty food choices, particularly for girls, according to a new study by Dr. Patricia Silveira and Prof. Michael Meaney of McGill University and Dr. Robert Levitan of the University of Toronto.

27 Nov 2013

Dopamine News and Research

Latest Dopamine News and Research

Continuing spinal cord stimulation improves symptoms of Parkinson's disease

Gene therapy edges closer for Parkinson’s disease

Deep-brain stimulation boosts PD patients’ driving performance

Neurovance announces interim results from phase 2a pilot study of EB-1020 SR in patients with all subtypes of ADHD

Antipsychotic medication can actively combat cells of difficult-to-treat form of ALL

Study raises hopes for new drugs to treat brain disorders associated with neurotransmitter imbalance

New ways to treat substance abuse, neurological diseases and mental illnesses

Molecule produced by brain acts as natural defence mechanism against cannabis

Parkinson's disease patients may find difficulties in recognizing emotions

Study investigates about emotions that affects patients with Parkinson's disease

New RUB project to unravel role of enzyme Parkin in promoting neuronal survival

DCC gene involved in adolescent brain development may play a role in mental health vulnerability

Researchers gain better understanding of neurochemical basis of addiction with optogenetics

Otsuka, Lundbeck to develop investigational vaccine candidate for Alzheimer's disease

Research highlights value of fathers in both neurobiology and behavior of offspring

Researchers discover how PC7 protein affects certain types of cognitive performance

Forest Laboratories to acquire exclusive rights in the U.S. for Saphris sublingual tablets

MRI provides noninvasive way to measure iron levels in the brains of ADHD people

Mutation in alpha-synuclein gene causes increased vulnerability to pesticides, leading to Parkinson's

Study links genetic predisposition to childhood obesity

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

Dopamine News and Research

Latest Dopamine News and Research

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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