Epigenetics News and Research

Latest Epigenetics News and Research

Link between dDsk2 protein and neurodegenerative diseases identified

Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression.

29 Apr 2015

Research findings may help identify genes that trigger BWS in humans

Humans and cattle share a similar epigenetic fetal overgrowth disorder that occurs more commonly following assisted reproduction procedures. In humans, this disorder is called Beckwith-Wiedemann syndrome (BWS), and in cattle it is called large offspring syndrome (LOS) and can result in the overgrowth of fetuses and enlarged babies.

29 Apr 2015

Researchers develop new IVF technique to improve fertility treatment

For couples struggling to conceive the old-fashioned way, in vitro fertilization (IVF) provides an alternate route to starting a family. When eggs are mixed with sperm in test tubes, the fertilized eggs to grow into embryos that can be implanted inside the uterus of a woman who will carry them to term.

29 Apr 2015

Scientists discover new way to control inflammation during worm infections and allergies

Research from The University of Manchester is bringing scientists a step closer to developing new therapies for controlling the body's response to allergies and parasitic worm infections.

25 Apr 2015

EMD Millipore launches Magna ChIRP RNA Interactome Kits for analyzing chromatin-associated RNAs

EMD Millipore, the Life Science business of Merck KGaA of Darmstadt, Germany, today introduced Magna ChIRP™ RNA Interactome Kits, which allow researchers to more easily identify, recover and analyze regions of chromatin that interact with chromatin-associated RNAs such as long non-coding RNA (lncRNA).

23 Apr 2015

Epigenetic processes influence children's later ability to learn and cognitive performance

Although it is now widely recognised that a poor start to life has long-term effects on a child's later ability to learn, the mechanisms by which the environment in early life affects later life chances are poorly understood.

23 Apr 2015

Purdue University study sheds light on how decitabine drug reverses cell damage

A Purdue University study sheds light on how cell damage is reversed by the cancer drug decitabine and identifies a potential biomarker that could indicate a patient's stage of cancer and response to treatment.

23 Apr 2015

Researchers provide new clues, mechanisms to understand functions of 'rebel' DNA in cancer

Genes usually always be expressed as in Western writing: from left to right on the white canvas of our DNA. So when we speak of the activity of our genome, in fact we are referring to the expression of genes in this sense of the double-stranded DNA.

22 Apr 2015

Global changes in cancer cells' epigenome may determine disease progression

Genomic studies have illuminated the ways in which malfunctioning genes can drive cancer growth while stunting the therapeutic effects of chemotherapy and other treatments. But new findings from Weill Cornell Medical College investigators indicate that these genes are only partly to blame for why treatment that was at one point effective ultimately fails for about 40 percent of patients diagnosed with the most common form of non-Hodgkin Lymphoma.

21 Apr 2015

Johns Hopkins researchers link sperm with specific 'epigenetic tags' to autism

In a small study, Johns Hopkins researchers found that DNA from the sperm of men whose children had early signs of autism shows distinct patterns of regulatory tags that could contribute to the condition. A detailed report of their findings will be published online in the International Journal of Epidemiology on April 15.

15 Apr 2015

VolitionRx adds three new laboratory automation systems to expedite sample analysis for its large ongoing clinical trials

Using its first installed robot, VolitionRx has recently completed the analysis of a first NuQ® assay on the complete set of 4,800 blood samples for its large retrospective, symptomatic population colorectal cancer study in collaboration with Hvidovre Hospital, University of Copenhagen, Denmark.

10 Apr 2015

Study: Key signaling pathway in B-cell lymphoma can be blocked using compounds

Cancer researchers from the University of Zurich have identified a key signaling pathway in B-cell lymphoma, a malignant type of blood cancer.

7 Apr 2015

High Throughput ChIP Sequencing

Chromatrap®, a business unit of Porvair Sciences, has announced a major product launch at the European Human Genetics Conference (Glasgow, UK) and the Festival of Genomics (Boston, USA) on the 6th June 2015 and 22nd-24th June 2015 respectively

From Chromatrap® - Porvair Sciences Ltd 6 Apr 2015

Adolescent binge-drinking alters genes needed for normal brain maturation

Binge-drinking during adolescence may perturb brain development at a critical time and leave lasting effects on genes and behavior that persist into adulthood.

3 Apr 2015

Old leukemia drug may help in fight against cancer

A drug used for decades to treat leukemia may have other uses in the fight against cancer, researchers at the University of Missouri have found. Previously, doctors used 6-Thioguanine, or 6-TG, as a chemotherapy treatment to kill cancer cells in patients with leukemia.

2 Apr 2015

CNIO researchers describe presence of MDH2 gene mutations in hereditary neuroendocrine tumors

Researchers in the Hereditary Endocrine Cancer Group of the Spanish National Cancer Research Centre -- led by Alberto Cascón and Mercedes Robledo -- have described the presence of mutations in the MDH2 gene, in a family with very rare neuroendocrine tumours associated with a high hereditary component: pheochromocytomas and paragangliomas that affect the suprarenal and parathyroid glands (groups of chromaffin cells in the central nervous system), respectively.

30 Mar 2015

CSHL professor to be honored with AACR Outstanding Achievement in Cancer Research Award

The American Association for Cancer Research will honor Christopher R. Vakoc, MD, PhD, assistant professor at Cold Spring Harbor Laboratory in Cold Spring Harbor, New York, with the 35th annual AACR Outstanding Achievement in Cancer Research Award at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22.

30 Mar 2015

Study: Blood test may help diagnose Fragile X syndrome related disorders in women

A blood test may shed new light on Fragile X syndrome related disorders in women, according to a new study published in the March 25, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. Fragile X is the most common inherited form of intellectual disability and the most frequent genetic cause of autism.

30 Mar 2015

Agena Bioscience releases LungFUSION Panel to identify gene fusions in NSCLC tumors

Agena Bioscience today released the LungFUSION Panel for rapid and sensitive identification of oncogenic ALK, RET, and ROS1 gene fusions in non-small cell lung cancer tumors.

25 Mar 2015

New approach to treating B-ALL tumour disease

B cell acute lymphoblastic leukaemia, or B-ALL, is the most common tumour disease in children and also occurs in adults. It develops when signalling pathways in immature B cells, or pre-B cells, are dysregulated. Prof. Dr. Markus Müschen from the University of California in San Francisco, USA, and his team worked together with the BIOSS researchers Prof. Dr. Hassan Jumaa and Prof. Dr. Michael Reth to find a new approach for treating the B-ALL tumour disease.

25 Mar 2015

Epigenetics News and Research

Latest Epigenetics News and Research

Link between dDsk2 protein and neurodegenerative diseases identified

Research findings may help identify genes that trigger BWS in humans

Researchers develop new IVF technique to improve fertility treatment

Scientists discover new way to control inflammation during worm infections and allergies

EMD Millipore launches Magna ChIRP RNA Interactome Kits for analyzing chromatin-associated RNAs

Epigenetic processes influence children's later ability to learn and cognitive performance

Purdue University study sheds light on how decitabine drug reverses cell damage

Researchers provide new clues, mechanisms to understand functions of 'rebel' DNA in cancer

Global changes in cancer cells' epigenome may determine disease progression

Johns Hopkins researchers link sperm with specific 'epigenetic tags' to autism

VolitionRx adds three new laboratory automation systems to expedite sample analysis for its large ongoing clinical trials

Study: Key signaling pathway in B-cell lymphoma can be blocked using compounds

High Throughput ChIP Sequencing

Adolescent binge-drinking alters genes needed for normal brain maturation

Old leukemia drug may help in fight against cancer

CNIO researchers describe presence of MDH2 gene mutations in hereditary neuroendocrine tumors

CSHL professor to be honored with AACR Outstanding Achievement in Cancer Research Award

Study: Blood test may help diagnose Fragile X syndrome related disorders in women

Agena Bioscience releases LungFUSION Panel to identify gene fusions in NSCLC tumors

New approach to treating B-ALL tumour disease

eBook: A guide to RNA sequencing eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Epigenetics News and Research

Latest Epigenetics News and Research

eBook: A guide to RNA sequencing eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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