Epigenetics

Epigenetics is the study of chemical reactions that influence gene expression, through activation or deactivation of genes at specific times and locations.

How Diet Influences Gene Expression Through Epigenetic Mechanisms

This article explains how diet creates sustained epigenetic changes that affect long-term health, disease risk, aging, and future environmental responses.

Effects of Social and Economic Deprivation on Cancer Mortality

What is Single-Molecule Real-Time (SMRT) Sequencing?

What is Nutritional Genomics (Nutrigenomics)?

ChIP-Seq Analysis: Histone Modifications

ChIP-seq Advantages and Limitations

The Role of Epigenetics in Human Disease

High-throughput single-cell DNA methylation profiling

Understanding the Role of Epigenetics in Cancer

See more featured articles »

How the Placenta Predicts Lifelong Health and Disease Risk

Systemic Telomere Length and Aging

Epigenetic Mechanisms in Type 2 Diabetes

What Is Epigenetic Reprogramming—and Could It Reverse Aging?

Age-Related Changes in Immune Function: Immunosenescence and Immune Modulation

Ovarian Aging Explained: Biological Age, Fertility, and Epigenetic Markers

Epigenetics for Multiple Sclerosis

Epigenetics in Drug Discovery: Modulating Gene Expression for Health

Effect of Environmental Toxicants on Developing Neurodegenerative Conditions

The 'Omics in Male Fertility Diagnostics

Cholangiocyte Biology and Its Implications in Cholangiopathies

Nutritional Epigenetics: How Food Shapes Genes Before Birth

Understanding Synthetic Epigenetics

Can Cannabis Use Alter Sperm DNA?

The Exposome Framework: Connecting Pollution, Diet, and Disease Pathways

How an Anti-Inflammatory Diet Lowers Chronic Disease Risk

Nutritional Epigenetics: How Food Shapes Genes Before Birth

Latest Epigenetics News and Research

Researchers explore "block and lock" strategy for functional HIV cure

For millions of people living with HIV, a daily regimen of medications is a lifelong necessity. If they stop taking the drugs-commonly referred to as antiretroviral therapy-the virus usually rushes back within weeks.

23 Mar 2026

Cancer cells rely on glutathione as fuel for growth

Researchers discovered an antioxidant, glutathione, that cancer cells appear to be "addicted to" as fuel, opening new pathways for investigation and a potential drug that can restrict the way tumors use this nutrient.

18 Mar 2026

New data platform transforms prediction and understanding of Alzheimer’s disease

A powerful new real-world data platform could transform how scientists predict and understand Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD), reports a new study at Columbia University Mailman School of Public Health and collaborators at the Vagelos College of Physicians and Surgeons, the School of Nursing as well as the University of Miami and University of Chicago.

18 Mar 2026

Scientists win awards for the discovery of genomic imprinting and tumor’s power grid

For their discovery of genomic imprinting, developmental biologists Davor Solter and Azim Surani will receive the 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, endowed with €120,000, on March 14 at Frankfurt’s Paulskirche.

13 Mar 2026

New review calls for biologically grounded approach to psychiatric diagnosis

A comprehensive invited review published today in Brain Medicine confronts one of the most persistent paradoxes in modern medicine: psychiatry remains the only major clinical discipline that diagnoses complex illness primarily through conversation and symptom checklists, while fields such as oncology and cardiology long ago embraced laboratory markers, imaging, and molecular profiling.

10 Mar 2026

Buck Institute launches a new initiative to measure and extend human healthspan

The Buck Institute for Research on Aging today announced the launch of Healthspan Horizons, a new initiative designed to address one of the most urgent challenges in modern medicine: how to measure, understand, and extend healthspan-the years of life spent in good health.

6 Mar 2026

New fragmentome technology can detect early liver fibrosis and cirrhosis

Researchers at the Johns Hopkins Kimmel Cancer Center report that an artificial intelligence (AI)-based liquid biopsy test using genome-wide cell-free DNA (cfDNA) fragmentation patterns and repeat landscapes can detect early liver fibrosis and cirrhosis, and may also reveal signals of broader chronic disease burden.

4 Mar 2026

ARPA-H-funded PROSPR program focuses on the biological hallmarks of aging

Columbia University Mailman School of Public Health has received an award as part of the PROactive Solutions for Prolonging Resilience (PROSPR) program within the Advanced Research Projects Agency for Health (ARPA-H) to accelerate research on the biological hallmarks of aging.

24 Feb 2026

Syndex Bio unveils mcPCR technology at AGBT 2026 following $15.5 M seed financing

Syndex Bio, a biotechnology company advancing next‑generation molecular diagnostics, today announced the introduction of its proprietary mcPCR™ (methyl‑copying PCR) platform at the Advances in Genome Biology and Technology (AGBT) conference in Orlando, Florida.

23 Feb 2026

Single prenatal exposure to fungicide linked to disease across 20 generations

A single exposure to a toxic fungicide during pregnancy can increase the risk of disease for 20 subsequent generations - with inherited health problems worsening many generations after exposure.

20 Feb 2026

Dual approach strengthens recovery for military PTSD

Military service members and veterans frequently experience post-traumatic stress disorder (PTSD), which is linked to a range of psychological challenges and adverse effects.

17 Feb 2026

'Partial reprogramming' of engram neurons restores memory performance in mice

Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible.

10 Feb 2026

Blocking p300 restores chemotherapy sensitivity in resistant tumors

Overcoming tumor resistance to chemotherapy drugs has long been a challenge for oncology clinicians and researchers.

6 Feb 2026

Estrogen levels in the brain may play a role in women’s risk of stress-related memory problems

Experiencing multiple acute stresses at the same time, as in natural disasters or mass shootings, can leave lasting memory scars.

3 Feb 2026

Neighborhood disadvantage accelerates biological aging through emotional distress

While scientists have long known that living in a disadvantaged neighborhood is associated with biological symptoms of accelerated aging, emotional distress accounts for a significant portion of these effects, researchers found in a recent study.

29 Jan 2026

Weill Cornell Medicine receives ARPA-H award to advance lymphatic disease diagnosis

Weill Cornell Medicine has received a $5.2 million, initial two-year award from the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics, and pHenotyping Technologies (LIGHT) program to develop a comprehensive and innovative approach to diagnosing lymphatic disease.

20 Jan 2026

AI analysis maps a century of global aging research

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 25, 2025, titled "A natural language processing–driven map of the aging research landscape."

23 Dec 2025

Younger epigenetic age linked to increased depression in older women

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 18, 2025, titled "Epigenetic age predicts depressive symptoms during the COVID-19 pandemic in the Canadian Longitudinal Study on Aging: importance of biological sex."

19 Dec 2025

Lysophosphatidylcholines show gene-dependent effects in early Alzheimer’s disease

A new study presents robust evidence on the role of lysophosphatidylcholines (LPCs) in the onset of Alzheimer's disease. Researchers discovered that LPCs-compounds that transport a variety of healthy fatty acids to the brain-either promote Alzheimer's or protect against it, depending on a person's genetics.

17 Dec 2025

Addition of tucatinib to the standard of care delays disease progression in HER2-positive metastatic breast cancer

Adding tucatinib (Tukysa) to first-line maintenance therapy with trastuzumab (Herceptin) and pertuzumab (Perjeta) delayed disease progression in patients with HER2-positive metastatic breast cancer, potentially extending time off chemotherapy, according to results from the phase III clinical trial HER2CLIMB-05 presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

10 Dec 2025