Epigenetics

Epigenetics is the study of chemical reactions that influence gene expression, through activation or deactivation of genes at specific times and locations.

Nutritional Epigenetics: How Food Shapes Genes Before Birth

Discover how a maternal diet can influence the development of the genome, revealing the scientific basis for prenatal nutrition as a cornerstone of disease prevention for future generations.

How an Anti-Inflammatory Diet Lowers Chronic Disease Risk

What is Single-Molecule Real-Time (SMRT) Sequencing?

Systemic Telomere Length and Aging

Understanding Synthetic Epigenetics

Epigenetics in Drug Discovery: Modulating Gene Expression for Health

Nutritional Epigenetics: How Food Shapes Genes Before Birth

Epigenetic Mechanisms in Type 2 Diabetes

See more featured articles »

ChIP-Seq Analysis: Histone Modifications

ChIP-seq Advantages and Limitations

What is Nutritional Genomics (Nutrigenomics)?

Can Cannabis Use Alter Sperm DNA?

Cholangiocyte Biology and Its Implications in Cholangiopathies

What Is Epigenetic Reprogramming—and Could It Reverse Aging?

The 'Omics in Male Fertility Diagnostics

Epigenetics for Multiple Sclerosis

High-throughput single-cell DNA methylation profiling

Understanding the Role of Epigenetics in Cancer

The Role of Epigenetics in Human Disease

Effects of Social and Economic Deprivation on Cancer Mortality

Effect of Environmental Toxicants on Developing Neurodegenerative Conditions

Age-Related Changes in Immune Function: Immunosenescence and Immune Modulation

Latest Epigenetics News and Research

AI analysis maps a century of global aging research

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 25, 2025, titled "A natural language processing–driven map of the aging research landscape."

23 Dec 2025

Younger epigenetic age linked to increased depression in older women

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 18, 2025, titled "Epigenetic age predicts depressive symptoms during the COVID-19 pandemic in the Canadian Longitudinal Study on Aging: importance of biological sex."

19 Dec 2025

Lysophosphatidylcholines show gene-dependent effects in early Alzheimer’s disease

A new study presents robust evidence on the role of lysophosphatidylcholines (LPCs) in the onset of Alzheimer's disease. Researchers discovered that LPCs-compounds that transport a variety of healthy fatty acids to the brain-either promote Alzheimer's or protect against it, depending on a person's genetics.

17 Dec 2025

Addition of tucatinib to the standard of care delays disease progression in HER2-positive metastatic breast cancer

Adding tucatinib (Tukysa) to first-line maintenance therapy with trastuzumab (Herceptin) and pertuzumab (Perjeta) delayed disease progression in patients with HER2-positive metastatic breast cancer, potentially extending time off chemotherapy, according to results from the phase III clinical trial HER2CLIMB-05 presented at the San Antonio Breast Cancer Symposium (SABCS), held December 9-12, 2025.

10 Dec 2025

Southeast Asia's first consortium launched to tackle dementia

Nanyang Technological University, Singapore (NTU Singapore) is leading 24 clinicians from the region and beyond to set up Southeast Asia's first consortium dedicated to tackling dementia.

28 Nov 2025

Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics-meticulously placed chemical tags that influence which genes are expressed in each cell.

22 Nov 2025

DeepTarget tool uncovers primary and secondary drug targets across cancer types

One person's side effect could be another person's treatment if we expand our perspective on small molecule drug targets, according to a new study published November 5, 2025, in npj Precision Oncology.

18 Nov 2025

DeepTarget: A new tool for drug repurposing in oncology

14 Nov 2025

Exploring m6A RNA modification as a therapeutic target in cardiovascular disorders

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs).

14 Nov 2025

Transforming colorectal cancer research with patient-derived xenograft models

Patient-derived xenograft (PDX) models are emerging as a transformative tool in colorectal cancer (CRC) research, offering unparalleled insights into tumor biology, drug resistance, and personalized treatment approaches.

14 Nov 2025

Bowel cancer’s “Big Bang” moment reveals how the disease takes shape

Like the astronomical explosion that kickstarted the universe, bowel cancer has a "Big Bang" moment which determines how it will grow, according to new research from Cancer Research UK and Wellcome Trust-funded scientists.

5 Nov 2025

Stress hormones may silence crucial neuronal genes through specific RNA molecules

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome's architecture.

4 Nov 2025

Review reveals how paternal lifestyle shapes sperm epigenetics and offspring health

A new review in Clinical Epigenetics synthesises growing evidence that paternal lifestyle and environmental exposures such as diet, obesity, smoking, endocrine-disrupting chemicals, and stress alter sperm epigenetic marks (DNA methylation, histone retention, and small non-coding RNAs).

17 Oct 2025

Multidimensional regulation of stem cell fate by the cohesin complex

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture.

10 Oct 2025

New GoT-Multi technology reveals how cancers evolve and resist treatment

A new tool developed by Weill Cornell Medicine and the University of Adelaide investigators has enhanced the ability to track multiple gene mutations while simultaneously recording gene activity in individual cancer cells.

10 Oct 2025

Takara Bio USA, Inc. announces a series of updates to its spatial biology product portfolio, extending its innovation with a new class of spatial technology

Takara Bio USA, Inc. ("Takara Bio USA"), a wholly owned subsidiary of Takara Bio Inc. ("Takara Bio"), today announced a series of updates to its spatial biology product portfolio, extending its innovation with a new class of spatial technology.

9 Oct 2025

Advancing precision medicine to transform obesity prevention and treatment

A new report led by researchers at Pennington Biomedical Research Center underscores the growing potential of precision medicine to transform how obesity is prevented, diagnosed and treated, while also illuminating key gaps and challenges that must be addressed.

6 Oct 2025

Study reveals new strategy to block TNBC metastasis and restore chromosomal stability

Triple negative breast cancer (TNBC) is one of the most aggressive and hardest forms of breast cancer to treat, but a new study led by Weill Cornell Medicine suggests a surprising way to stop it from spreading. Researchers have discovered that an enzyme called EZH2 drives TNBC cells to divide abnormally, which enables them to relocate to distant organs.

6 Oct 2025

Research highlights how the gut microbiome can affect epigenetics

The trillions of microbes that live in the human gut may play a bigger role in health than previously thought, according to a new research by the University of Hawaiʻi at Mānoa.

23 Sep 2025