Epigenetics

Epigenetics is the study of chemical reactions that influence gene expression, through activation or deactivation of genes at specific times and locations.

How Diet Influences Gene Expression Through Epigenetic Mechanisms

This article explains how diet creates sustained epigenetic changes that affect long-term health, disease risk, aging, and future environmental responses.

The Exposome Framework: Connecting Pollution, Diet, and Disease Pathways

Understanding Synthetic Epigenetics

The Role of Epigenetics in Human Disease

High-throughput single-cell DNA methylation profiling

ChIP-seq Advantages and Limitations

Understanding the Role of Epigenetics in Cancer

Epigenetics for Multiple Sclerosis

See more featured articles »

Effect of Environmental Toxicants on Developing Neurodegenerative Conditions

The 'Omics in Male Fertility Diagnostics

Nutritional Epigenetics: How Food Shapes Genes Before Birth

Effects of Social and Economic Deprivation on Cancer Mortality

Age-Related Changes in Immune Function: Immunosenescence and Immune Modulation

Cholangiocyte Biology and Its Implications in Cholangiopathies

ChIP-Seq Analysis: Histone Modifications

Epigenetic Mechanisms in Type 2 Diabetes

Can Cannabis Use Alter Sperm DNA?

Epigenetics in Drug Discovery: Modulating Gene Expression for Health

Ovarian Aging Explained: Biological Age, Fertility, and Epigenetic Markers

How an Anti-Inflammatory Diet Lowers Chronic Disease Risk

Systemic Telomere Length and Aging

Nutritional Epigenetics: How Food Shapes Genes Before Birth

How the Placenta Predicts Lifelong Health and Disease Risk

What Is Epigenetic Reprogramming—and Could It Reverse Aging?

What is Single-Molecule Real-Time (SMRT) Sequencing?

What is Nutritional Genomics (Nutrigenomics)?

Latest Epigenetics News and Research

New machine learning model improves accuracy of prenatal genetic testing

Advances in genome sequencing are giving more families access to prenatal genetic testing and new information about an unborn baby's health, including whether genetic changes may link to a neurodevelopmental condition.

11 Aug 2026

Early-life stress rewires brain epigenetics to heighten sensitivity to future stress

. Early-life stress increased SETD7 and H3K4me1 in the ventral tegmental area of mice, creating an epigenetically primed state that heightened later transcriptional, neuronal, and behavioral responses to stress. Reducing Setd7 during development lowered H3K4me1 and weakened these stress-sensitizing effects, identifying a mechanism that may help explain how early adversity leaves lasting biological effects.

11 Aug 2026

Piezo ion channels: Key regulators of digestive health and disease

Mechanosensitive Piezo ion channels, particularly Piezo1 and Piezo2, are gaining recognition as central regulators of digestive system physiology and disease.

7 Aug 2026

New review explores purinergic signaling pathways in osteoarthritis progression

A growing understanding of purinergic signaling is reshaping how scientists view osteoarthritis (OA), revealing an intricate communication network that influences joint inflammation, cartilage degeneration, bone remodeling, and chronic pain.

7 Aug 2026

Exhausted T cells balance graft tolerance and infection risk

A comprehensive new review examines the complex role of T cell exhaustion in organ transplantation, highlighting how this dysfunctional immune state can both promote graft tolerance and create vulnerabilities to infection and malignancy.

7 Aug 2026

Disrupted RNA methylation pathway accelerates Alzheimer’s and Parkinson’s risks

A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development, and neurodegenerative disease.

7 Aug 2026

Metabolic stress triggers long-lasting immune system changes in diabetes patients

A growing understanding of trained immunity, a form of long-lasting immune system adaptation, is reshaping how scientists view diabetes and its many complications.

7 Aug 2026

Autophagy modulation emerges as a strategy against cisplatin-resistant gastric cancer

Drug resistance remains one of the greatest obstacles to successful treatment of gastric cancer, limiting the long-term effectiveness of the widely used chemotherapy drug cisplatin.

6 Aug 2026

Tuft cell-like cancers exhibit unique biological characteristics across multiple organs

A growing body of evidence suggests that a rare epithelial cell type known as the tuft cell may play a far more significant role in cancer than previously recognized.

6 Aug 2026

PIWI proteins and piRNAs may unlock more effective stem cell therapies

Scientists are shedding new light on a little-known biological system that could help unlock the full potential of stem cell therapy, one of the most promising areas of modern medicine.

6 Aug 2026

New review links obesity with accelerated biological aging mechanisms

The global rise in obesity and population aging represents a major public health challenge, with growing evidence suggesting that excess body fat not only increases the risk of chronic disease but may also accelerate the biological aging process.

6 Aug 2026

New review advances understanding of biological mechanisms driving Ménière's disease

A comprehensive new review is bringing together the latest advances in Ménière's disease, offering a clearer picture of the biological mechanisms that may drive this complex inner ear disorder while highlighting new directions for diagnosis, disease modeling, and treatment.

6 Aug 2026