Epigenetics News and Research

Latest Epigenetics News and Research

New regulatory mechanism could help develop novel therapies for cancer

Molecular microbiologists at the University of Southern California (USC) have uncovered intricate regulatory mechanisms within the cell that could lead to novel therapeutics for the treatment of cancer and other diseases.

23 Sep 2013

Boys’ chronic aggressive behavior may be due to epigenetic changes during pregnancy, early childhood

Chronic aggressive behaviour exhibited by some boys from disadvantaged families may be due to epigenetic changes during pregnancy and early childhood.

23 Sep 2013

Study shows how lifestyle factors can influence metabolism via resulting alterations in DNA

In the course of life, aging processes, environmental influences and lifestyle factors such as smoking or diet induce biochemical alterations to the DNA. Frequently, these lead to DNA methylation, a process in which methyl groups are added to particular DNA segments, without changing the DNA sequence.

21 Sep 2013

Discovery of gene essential for memory extinction could lead to new PTSD treatments

If you got beat up by a bully on your walk home from school every day, you would probably become very afraid of the spot where you usually met him. However, if the bully moved out of town, you would gradually cease to fear that area.

19 Sep 2013

FDA grants Breakthrough Therapy designation to Boehringer Ingelheim's volasertib

Boehringer Ingelheim Pharmaceuticals, Inc. today announced the FDA has granted Breakthrough Therapy designation to volasertib, an investigational inhibitor of polo-like kinase, being evaluated for the treatment of patients aged 65 or older with previously untreated acute myeloid leukemia, ineligible for intensive remission induction therapy.

17 Sep 2013

Protein plays important role in process of degradation of tumour cells, say researchers

When tumour cells no longer degrade themselves, cancer may develop. Using black skin cancer as an example, Bern Researchers have now shown that a protein plays an important role in the process of degradation of tumour cells. By reactivating this degradation therapeutically, you can virtually force tumours to digest themselves.

12 Sep 2013

FDA grants Breakthrough Therapy designation to Syndax's entinostat for ER+ breast cancer

Syndax Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration has designated entinostat as a Breakthrough Therapy for the treatment of locally recurrent or metastatic estrogen receptor-positive (ER+) breast cancer when added to exemestane in postmenopausal women whose disease has progressed following non-steroidal aromatase inhibitor therapy.

12 Sep 2013

Experimental agent fails to increase HDL levels, reveals new study

The search continues for an agent that increases high-density lipoprotein (HDL) and reduces arterial plaque, after the experimental apolipoprotein A1 (apoA1) inducer, RVX-208 failed to do so in the ApoA1 Synthesis Stimulation and Intravascular Ultrasound for Coronary Atheroma Regression Evaluation (ASSURE) study.

5 Sep 2013

Sigma Life Science signs license agreement with Horizon Discovery for CompoZr ZFN technology

Sigma-Aldrich Corporation today announced that Sigma Life Science, its innovative biological products and services business, has entered a non-exclusive license agreement with Horizon Discovery for use of Sigma's CompoZr Zinc Finger Nuclease technology.

3 Sep 2013

Cambridge Epigenetix’s pioneering TrueMethyl™ kit proves successful in beta trial

Cambridge Epigenetix Ltd. (CEGX), a leader in epigenetics tools innovation, today published the results of a successful beta trial evaluating their pioneering TrueMethyl™ oxidative bisulfite sequencing (oxBS-Seq) technology.

3 Sep 2013

Researchers discover role played by epigenetic factors in senescence and age-related diseases

One way cells promote tumor suppression is through a process called senescence, an irreversible arrest of proliferation. Senescence is thought to be associated with normal aging, but is also a protective measure by the body against run-away cell replication.

31 Aug 2013

Study provides first genomic characterization of remission in juvenile rheumatoid arthritis patients

More children with juvenile rheumatoid arthritis are experiencing remission of their symptoms, thanks to new biological therapies, but the remission is not well-understood. A new study published today in Arthritis Research & Therapy provides the first genomic characterization of remission in juvenile rheumatoid arthritis patients.

30 Aug 2013

Dieting before getting pregnant not enough to prevent diabetes risks

Bethesda, MD-While there is never a bad time to address one's own obesity, if you're hoping to lose weight before conception for the sake of your child, here's some bad news: Some of the epigenetic damage might have already been done, even if you lose the weight just before conception.

30 Aug 2013

Sigma Life Science releases genome editing tool for screening and exploratory studies

Sigma-Aldrich Corporation today announced that Sigma Life Science, its innovative biological products and services business, released Sigma CRISPRs, an inexpensive mammalian genome editing tool suitable for screening and exploratory studies.

27 Aug 2013

Scientists discover crucial role of nitric oxide in cellular signaling and health

Scientists at the University of Illinois at Chicago College of Pharmacy have discovered a new role for nitric oxide, a gas molecule crucial for cellular signaling and health.

26 Aug 2013

Researchers find new strategy that has potential to change standard of care for DLBCL patients

Patients with an aggressive lymphoma that often relapses and kills within two years experienced a remission of their cancer and stayed disease-free as long as 28 months after taking a commercially-available drug that made chemotherapy more effective.

20 Aug 2013

New type of cancer immunotherapy harnesses body's immune system to attack tumors

By carefully adjusting the function of crucial immune cells, scientists may have developed a completely new type of cancer immunotherapy—harnessing the body's immune system to attack tumors. To accomplish this, they had to thread a needle in immune function, shrinking tumors without triggering unwanted autoimmune responses.

19 Aug 2013

Researchers provide support for potential importance of vitamin D in pregnancy

Researchers at the MRC Lifecourse Epidemiology Unit, University of Southampton, have demonstrated that the degree to which a gene related to vitamin D action is switched on or off, when measured at birth, predicts bone density of the child at four years of age.

16 Aug 2013

Study shows enhancer RNA molecules may open new avenues for gene therapy

A study investigating the function of the recently discovered enhancer RNA molecules may open new avenues for gene therapy. According to the study researchers, altering the production and function of these molecules could affect the expression of genes and, in consequence, possibly also the progression of various diseases.

14 Aug 2013

Study shows how bioactive component in soy foods plays a role against colon cancer

University of Illinois scientists have evidence that lifelong exposure to genistein, a bioactive component in soy foods, protects against colon cancer by repressing a signal that leads to accelerated growth of cells, polyps, and eventually malignant tumors.

6 Aug 2013

Epigenetics News and Research

Latest Epigenetics News and Research

New regulatory mechanism could help develop novel therapies for cancer

Boys’ chronic aggressive behavior may be due to epigenetic changes during pregnancy, early childhood

Study shows how lifestyle factors can influence metabolism via resulting alterations in DNA

Discovery of gene essential for memory extinction could lead to new PTSD treatments

FDA grants Breakthrough Therapy designation to Boehringer Ingelheim's volasertib

Protein plays important role in process of degradation of tumour cells, say researchers

FDA grants Breakthrough Therapy designation to Syndax's entinostat for ER+ breast cancer

Experimental agent fails to increase HDL levels, reveals new study

Sigma Life Science signs license agreement with Horizon Discovery for CompoZr ZFN technology

Cambridge Epigenetix’s pioneering TrueMethyl™ kit proves successful in beta trial

Researchers discover role played by epigenetic factors in senescence and age-related diseases

Study provides first genomic characterization of remission in juvenile rheumatoid arthritis patients

Dieting before getting pregnant not enough to prevent diabetes risks

Sigma Life Science releases genome editing tool for screening and exploratory studies

Scientists discover crucial role of nitric oxide in cellular signaling and health

Researchers find new strategy that has potential to change standard of care for DLBCL patients

New type of cancer immunotherapy harnesses body's immune system to attack tumors

Researchers provide support for potential importance of vitamin D in pregnancy

Study shows enhancer RNA molecules may open new avenues for gene therapy

Study shows how bioactive component in soy foods plays a role against colon cancer

eBook: A guide to RNA sequencing eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

Epigenetics News and Research

Latest Epigenetics News and Research

eBook: A guide to RNA sequencing eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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