Estrogen News and Research

Latest Estrogen News and Research

‘Terminator’ protein suppresses tumorigenesis

Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.

3 Jun 2020

Study: High estrogen levels may influence alcohol use disorder

A new study from researchers at the University of Illinois at Chicago shows that high estrogen levels may make alcohol more rewarding to female mice.

2 Jun 2020

Targeted drugs shrink breast cancer tumors in mice without toxic side effects

A team of researchers led by Worcester Polytechnic Institute Provost Wole Soboyejo has identified targeted drugs that reduced the sizes of hard-to-treat breast cancer tumors in mice without inducing the toxic side effects that are typically associated with conventional chemotherapy.

28 May 2020

Fluctuating estrogen levels could make alcohol more rewarding to women

Fluctuating estrogen levels may make alcohol more rewarding to female mice, according to new research in JNeurosci. Untangling the involved signaling pathways could unveil sex-based treatments for alcohol use disorders.

28 May 2020

New therapeutic approach for aggressive breast cancer

This type of TNBC tumor does not express any of the receptors involved in most breast cancers (estrogen, progesterone and HER2), so the most common treatments, such as the hormone therapy, are not viable in these patients.

25 May 2020

Scientists create a detailed map of how carcinogens trigger breast cancer development

In the most comprehensive review to date of how breast cancer develops, scientists have created a detailed map that describes the many ways in which environmental chemicals can trigger the disease.

21 May 2020

Researchers identify determining factor in luminal cancer cells

The Translational Control of Cell Cycle and Differentiation Lab at IRB Barcelona, led by ICREA researcher Raúl Méndez, has published a study in the journal Science Advances that has identified a key factor in the development of luminal breast cancer.

18 May 2020

New analysis links DNA variations to risks of specific breast cancer subtypes

An analysis of genetic studies covering 266,000 women has revealed 32 new sites on the human genome where variations in DNA appear to alter the risks of getting breast cancer.

18 May 2020

Roswell Park team proposes possible new strategy for treating pancreatic cancer

A possible new strategy for treating pancreatic cancer highlights the promise of collaboration between experts in both precision medicine and immunology.

18 May 2020

Chasing the elusive dream of a COVID cure

Although scientists and stock markets have celebrated the approval for emergency use of remdesivir to treat COVID-19, a cure for the disease that has killed nearly 260,000 people remains a long way off — and might never arrive.

15 May 2020

Text reminders are not a silver bullet to improve breast cancer hormone therapy adherence

Text message reminders are not a silver bullet when it comes to overcoming the long-standing challenge of ensuring that breast cancer patients continue to take aromatase inhibitors, pills to treat hormone-sensitive cancers that are prescribed for as long as five years.

14 May 2020

Woman's genetic make-up may play a role in weight gain from birth control

A woman's genetic make-up may cause her to gain weight when using a popular form of birth control, according to a study from researchers at the University of Colorado Anschutz Medical Campus.

12 May 2020

Novel anti-cancer medicine could improve current therapy for ER+ breast cancer

The anti-cancer medicine venetoclax could improve the current therapy for estrogen receptor-positive breast cancer - the most common form of breast cancer in Australia - according to preclinical studies led by Walter and Eliza Hall Institute researchers.

8 May 2020

Harmful effects of BPA can be reversed by administering coenzyme Q10

Exposure to bisphenol A (BPA), an industrial chemical used to make certain plastics and resins, inner coatings for food cans and bottle tops, thermal paper used in store receipts, dental sealants and so on, is a concern because of possible adverse health effects, including a reduction in fertility.

7 May 2020

Activation of estrogen receptor can impede growth of pancreatic cancer cells

Activating the G protein-coupled estrogen receptor - a receptor found on the surface of many normal and cancer tissues - has been shown to stop pancreatic cancer from growing, but may also make tumors more visible to the immune system and thus more susceptible to modern immunotherapy.

4 May 2020

Study: Unique glucose-sensing neurons in the brain prevent severe hypoglycemia

Low blood sugar levels, known as hypoglycemia, can be a life-threatening situation, especially for people with type 1 diabetes who rely on intensive insulin therapy to prevent blood sugar from going too high.

4 May 2020

Immunotherapy before surgery may help eradicate high-risk breast cancer

A new study led by Yale Cancer Center researchers shows women with high-risk HER2-negative breast cancer treated before surgery with immunotherapy, plus a PARP inhibitor with chemotherapy, have a higher rate of complete eradication of cancer from the breast and lymph nodes compared to chemotherapy alone.

28 Apr 2020

AMPK activation by anti-diabetes drug promotes survival of dormant breast cancer cells

Most breast cancers utilize the female hormone estrogen to grow, so drug-induced estrogen deprivation is used as a treatment in many patients. However, cancer will recur in one-third of these patients.

22 Apr 2020

Reprimo gene may play a role in menopause-related weight gain

A new study published in the journal Nature Metabolism in April 2020 indicates that some genes could allow women in menopause to remain healthy without hormone replacement therapy, which has been linked to a higher risk of heart disease and breast cancer.

13 Apr 2020

Columbia University launches CovidWatcher app to track virus spread in NYC

Researchers from Columbia University have launched CovidWatcher, an app that surveys users about their exposure to the new coronavirus, symptoms, access to medical care, and impact on daily life.

13 Apr 2020