Fatty Liver News and Research

Latest Fatty Liver News and Research

Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

Scientists of the German Center for Diabetes Research led by the German Institute of Human Nutrition have shown in a mouse model that the epigenetic modification of the Igfbp2 gene observed in the young animal precedes a fatty liver in the adult animal later in life.

24 May 2016

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Prediabetes is associated with increased risk of diabetes, cardiovascular disease, dementia and cancer. However, the disease risk considerably varies among subjects.

21 May 2016

Clinical study shows sitagliptin drug not effective in treating NAFLD

A diabetes medication described in some studies as an effective treatment for nonalcoholic fatty liver disease (NAFLD) works no better than a placebo, report researchers at University of California San Diego School of Medicine, after conducting the first randomized, double-blind, controlled clinical trial of sitagliptin, an oral antihyperglycemic marketed by Merck & Co. under the name Januvia.

13 May 2016

Food deprivation may help treat fatty liver disease

Scientists at Helmholtz Zentrum München have new information on what happens at the molecular level when we go hungry. Working with the Deutsches Zentrum für Diabetesforschung and the Deutsches Krebsforschungszentrum they were able to show that upon deprivation of food a certain protein is produced that adjusts the metabolism in the liver.

9 May 2016

Serum marker may flag liver fibrosis in chronic HBV

Serum levels of Wisteria floribunda agglutinin-positive Mac-2-binding protein may reflect the severity of liver fibrosis in patients with chronic hepatitis B virus infection, say researchers.

27 Apr 2016

Daily dose of coffee could help reverse non-alcoholic fatty liver disease

Adding coffee to the diet of people with non-alcoholic fatty liver disease (NAFLD) could help reverse the condition, according to a new study conducted in mice presented at The International Liver Congress 2016 in Barcelona, Spain.

13 Apr 2016

New research shows type 2 diabetes as important risk factor for chronic liver disease

People with type 2 diabetes are at greater risk of serious liver disease than those without the condition, new research has shown.

13 Apr 2016

Newcastle scientists develop new type of genetic blood test to diagnose liver scarring

Newcastle scientists and medics have developed a new type of genetic blood test that diagnoses scarring in the liver - even before someone may feel ill.

11 Apr 2016

3D MRE offers accurate non-invasive method to detect advanced fibrosis

Nonalcoholic fatty liver disease, or NAFLD, comprises a group of liver disorders whose prevalence is widespread and rising. It's estimated that at least one-third of Americans have NAFLD; among obese persons, the figure is 50 percent.

6 Apr 2016

Researchers find prevalence of steatosis in liver transplant recipients

Researchers have characterized the prevalence and risk factors of fatty liver disease in patients who undergo liver transplantation. The findings, which are published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases, could have important implications for safeguarding transplant recipients' health.

6 Apr 2016

UCSF study marks important step toward finding cure for Ebola

In experiments carried out partly at the Department of Energy's SLAC National Accelerator Laboratory, scientists have determined in atomic detail how a potential drug molecule fits into and blocks a channel in cell membranes that Ebola and related "filoviruses" need to infect victims' cells.

15 Mar 2016

Absence of PEMT enzyme leads to development of fatty liver disease and tumours in thin patients

Researchers observe protection against obesity and insulin resistance but at the cost of prominent fatty liver disease in mice lacking the PEMT enzyme and patients with low levels of PEMT.

7 Mar 2016

Inherited gene after black plague may help treat HIV patients co-infected with hepatitis C

The Black Death swept Europe in the 14th century eliminating up to half of the population but it left genetic clues that now may aid a University of Cincinnati researcher in treating HIV patients co-infected with hepatitis C using an anti-retroviral drug therapy.

7 Mar 2016

P53 genetic variant heavily implicated in metabolism, new research finds

The study may also provide an evolutionary explanation for differences in populations living farther away from the Equator. Human ancestors may have undergone this change in R72 to promote energy storage in cold climates and during times of famine. However, in modern society, the need for this type of variant in our genes is unnecessary, leading instead to increased risk for obesity and type 2 diabetes. Obesity is also a risk factor for certain types of cancer, so these findings may also explain why the R72 variant of p53 might predispose certain people to cancer.

4 Mar 2016

Dietary broccoli may protect against liver cancer

Consumption of broccoli has increased in the United States over the last few decades as scientists have reported that eating the vegetable three to five times per week can lower the risk of many types of cancer including breast, prostate, and colon cancers.

4 Mar 2016

Isomaltulose more suitable than table sugar for people with type 2 diabetes

Potsdam-Rehbruecke - Like sucrose (table sugar), the natural disaccharide isomaltulose (PalatinoseTM) consists of glucose and fructose, but it is apparently more suitable for people with type 2 diabetes with regard to regulating blood glucose levels.

17 Feb 2016

Aerobic exercise may prevent alcohol-related liver damage

According to the Centers for Disease Control and Prevention, excessive alcohol use is responsible for more than 80,000 deaths in the United States each year. Over time, excessive drinking can lead to several chronic conditions, such as fatty liver disease and cirrhosis.

16 Feb 2016

Alcohol appears to impair the body's ability to keep gut bacteria in check

Alcohol itself can directly damage liver cells. Now researchers at University of California, San Diego School of Medicine report evidence that alcohol is also harmful to the liver for a second reason — it allows gut bacteria to migrate to the liver, promoting alcohol-induced liver disease.

11 Feb 2016

UC San Diego School of Medicine launches new NAFLD Research Center

Roughly one-quarter of all Americans - an estimated 100 million adults and children - have nonalcoholic fatty liver disease (NAFLD), a chronic condition that can lead to cirrhosis, liver cancer and liver failure.

9 Feb 2016

Incidence and severity emerging CVD risk factors may differ between genders

The incidence and severity of both traditional and emerging cardiovascular disease (CVD) risk factors as well as the response to treatment may differ between genders. In this narrative review, several emerging CVD risk factors (i.e. inflammatory and haemostatic markers, endothelial dysfunction, homocysteine, lipid disorders, microalbuminuria/proteinuria, coronary artery calcium score, arterial stiffness, periodontitis, inflammatory bowel syndrome, obstructive sleep apnea, impaired glucose metabolism, metabolic syndrome and non-alcoholic fatty liver disease) are discussed in the context of gender differences.

5 Feb 2016

Fatty Liver News and Research

Latest Fatty Liver News and Research

Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Clinical study shows sitagliptin drug not effective in treating NAFLD

Food deprivation may help treat fatty liver disease

Serum marker may flag liver fibrosis in chronic HBV

Daily dose of coffee could help reverse non-alcoholic fatty liver disease

New research shows type 2 diabetes as important risk factor for chronic liver disease

Newcastle scientists develop new type of genetic blood test to diagnose liver scarring

3D MRE offers accurate non-invasive method to detect advanced fibrosis

Researchers find prevalence of steatosis in liver transplant recipients

UCSF study marks important step toward finding cure for Ebola

Absence of PEMT enzyme leads to development of fatty liver disease and tumours in thin patients

Inherited gene after black plague may help treat HIV patients co-infected with hepatitis C

P53 genetic variant heavily implicated in metabolism, new research finds

Dietary broccoli may protect against liver cancer

Isomaltulose more suitable than table sugar for people with type 2 diabetes

Aerobic exercise may prevent alcohol-related liver damage

Alcohol appears to impair the body's ability to keep gut bacteria in check

UC San Diego School of Medicine launches new NAFLD Research Center

Incidence and severity emerging CVD risk factors may differ between genders

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Fatty Liver News and Research

Latest Fatty Liver News and Research

Innovation in neuroscience drug discovery - eBook eBook

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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